MX9804305A - Analisis sanguineo de proporcion del factor v paradeterminar la susceptibilidad a la tromboembolia. - Google Patents

Analisis sanguineo de proporcion del factor v paradeterminar la susceptibilidad a la tromboembolia.

Info

Publication number
MX9804305A
MX9804305A MX9804305A MX9804305A MX9804305A MX 9804305 A MX9804305 A MX 9804305A MX 9804305 A MX9804305 A MX 9804305A MX 9804305 A MX9804305 A MX 9804305A MX 9804305 A MX9804305 A MX 9804305A
Authority
MX
Mexico
Prior art keywords
factor
defect
individuals
apc
ratio
Prior art date
Application number
MX9804305A
Other languages
English (en)
Inventor
Yale S Arkel
Dehui Wayne Ku
Original Assignee
Ahs Hospital Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21728263&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX9804305(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ahs Hospital Corp filed Critical Ahs Hospital Corp
Publication of MX9804305A publication Critical patent/MX9804305A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
    • G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
    • G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
    • G01N2333/96433—Serine endopeptidases (3.4.21)
    • G01N2333/96441—Serine endopeptidases (3.4.21) with definite EC number
    • G01N2333/96461—Protein C (3.4.21.69)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
    • G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
    • G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
    • G01N2333/96433—Serine endopeptidases (3.4.21)
    • G01N2333/96441—Serine endopeptidases (3.4.21) with definite EC number
    • G01N2333/96463—Blood coagulation factors not provided for in a preceding group or according to more than one of the proceeding groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Neurosurgery (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Se describe la determinacion en sangre de la Proporcion del Factor V (FVR) (léase "proporcion del factor cinco") y los estuches para la realizacion del mismo que identifican a los individuos que poseen una deficiencia genética específica, conocida como la deficiencia del Factor V de Leiden, u otra deficiencia del Factor V genética o adquirida, que hacen a estos individuos propensos a la tromboembolia venosa. En este análisis, se compara la actividad de Factor V de una muestra de plasma sanguínea expuesta a la Proteína C activada (APC) con la actividad de factor V de una muestra similar en ausencia de APC, luego de que ambas muestras han sido tratadas con un agente activador. La proporcion entre el nivel de actividad del Factor V sin APC y el nivel de actividad de Factor V con APC, identifica a los individuos que se encuentran en riesgo de sufrir una afeccion trombática debido a la deficiencia de Factor V y diferencia a los individuos con una deficiencia heteoocigotica de los individuos con una deficiencia homocigotica.
MX9804305A 1995-11-30 1998-05-29 Analisis sanguineo de proporcion del factor v paradeterminar la susceptibilidad a la tromboembolia. MX9804305A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US781595P 1995-11-30 1995-11-30

Publications (1)

Publication Number Publication Date
MX9804305A true MX9804305A (es) 1998-11-30

Family

ID=21728263

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9804305A MX9804305A (es) 1995-11-30 1998-05-29 Analisis sanguineo de proporcion del factor v paradeterminar la susceptibilidad a la tromboembolia.

Country Status (12)

Country Link
US (1) US5766869A (es)
EP (1) EP0873418B1 (es)
AR (1) AR004826A1 (es)
AT (1) ATE254666T1 (es)
AU (1) AU1055697A (es)
CA (1) CA2238814A1 (es)
DE (1) DE69630808D1 (es)
EA (1) EA000673B1 (es)
IL (1) IL124662A (es)
MX (1) MX9804305A (es)
PL (1) PL327006A1 (es)
WO (1) WO1997020066A1 (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2154080C (en) * 1993-01-29 2006-03-21 Bjorn Dahlback Novel anticoagulant cofactor activity
EP0696325B1 (en) * 1994-02-14 1998-05-13 Rijksuniversiteit Leiden A method for screening for the presence of a genetic defect associated with thrombosis and/or poor anticoagulant response to activated protein c
US5708591A (en) * 1995-02-14 1998-01-13 Akzo Nobel N.V. Method and apparatus for predicting the presence of congenital and acquired imbalances and therapeutic conditions
US6429017B1 (en) 1999-02-04 2002-08-06 Biomerieux Method for predicting the presence of haemostatic dysfunction in a patient sample
US6898532B1 (en) 1995-06-07 2005-05-24 Biomerieux, Inc. Method and apparatus for predicting the presence of haemostatic dysfunction in a patient sample
US6321164B1 (en) 1995-06-07 2001-11-20 Akzo Nobel N.V. Method and apparatus for predicting the presence of an abnormal level of one or more proteins in the clotting cascade
US6379975B1 (en) 1996-11-27 2002-04-30 T.A.C. Thrombosis And Coagulation Aktiebolag Methods and reagents for determining protein S
AT405692B (de) * 1997-03-27 1999-10-25 Immuno Ag Reagens zur bestimmung der aptt
US6502040B2 (en) 1997-12-31 2002-12-31 Biomerieux, Inc. Method for presenting thrombosis and hemostasis assay data
ATE282208T1 (de) 1999-02-04 2004-11-15 Bio Merieux Inc Verfahren und vorrichtung zum vorhersagen von haemostatischer funktionsstörung in patientenproben
US7179612B2 (en) 2000-06-09 2007-02-20 Biomerieux, Inc. Method for detecting a lipoprotein-acute phase protein complex and predicting an increased risk of system failure or mortality
US6855509B2 (en) * 2000-12-19 2005-02-15 Instrumentation Laboratory Company Protein S functional assay and kit therefor
WO2003061605A2 (en) * 2002-01-17 2003-07-31 R.E.D. Laboratories, N.V./S.A. Methods of treatment of chronic immune disease
US20050026168A1 (en) * 2002-12-13 2005-02-03 Genesis Group Inc. Method for the detection of risk factors associated with myocardial infarction
WO2007018511A1 (en) * 2005-07-28 2007-02-15 American Diagnostica Inc. Lupus anticoagulant testing
US7932021B2 (en) * 2005-07-28 2011-04-26 American Diagnostica, Inc. Lupus anticoagulant testing
EP3418390A1 (en) 2013-05-14 2018-12-26 Struszym S.L. Test strips for determining coagulation factor activities
EP3839059A1 (en) * 2019-12-16 2021-06-23 CGT Enterprises, LLC Devices and methods for determining coagulation factor activities

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3516579A1 (de) * 1984-11-19 1986-05-22 Boehringer Mannheim Gmbh, 6800 Mannheim Gerinnungstest auf teststreifen
US4948724A (en) * 1985-09-05 1990-08-14 Yin E Thye Composition, kit and method for assaying heparin and a method for making the composition
US5472850A (en) * 1991-04-10 1995-12-05 Oklahoma Medical Research Foundation Quantitative clotting assay for activated factor VII
US5051357A (en) * 1989-07-14 1991-09-24 Board Of Trustees Operating Michigan State University Method and assay using inactivation of factors Va and VIIIa by activated Protein C to diagnose thrombic disease or assay for Protein C and kit therefor
SE464135B (sv) * 1989-07-14 1991-03-11 Kabivitrum Ab Foerfarande foer bestaemning av funktionell aktivitet av fritt protein s eller protein c i ett plasmaprov
US5169786A (en) * 1989-12-19 1992-12-08 Ortho Diagnostic Systems, Inc. Method of determining levels of extrinsic and intrinsic clotting factors and protein c
WO1993007491A1 (en) * 1991-10-04 1993-04-15 Board Of Regents Of The University Of Nebraska A soluble thrombomodulin-based one-stage assay for vitamin k-dependent coagulation-inhibiting proteins
SE470274B (sv) * 1991-11-13 1993-12-20 Bjoern Dahlbaeck Användning av en in vitro-metod för diagnos av blodkoagulationssjukdomar
EP0585504A1 (en) * 1992-09-04 1994-03-09 Pentapharm A.G. Phospholipid dependant prothrombin activator and its use in lupus anticoagulant testing
CA2154080C (en) * 1993-01-29 2006-03-21 Bjorn Dahlback Novel anticoagulant cofactor activity
US5472852A (en) * 1993-09-15 1995-12-05 Oklahoma Medical Research Foundation Assay for detection of selective Protein C inhibition by patients
EP0696325B1 (en) * 1994-02-14 1998-05-13 Rijksuniversiteit Leiden A method for screening for the presence of a genetic defect associated with thrombosis and/or poor anticoagulant response to activated protein c
US5418141A (en) * 1994-05-06 1995-05-23 Avocet Medical, Inc. Test articles for performing dry reagent prothrombin time assays
US5705395A (en) * 1994-11-14 1998-01-06 The Scripps Research Institute Method for diagnosis of thrombotic disorders

Also Published As

Publication number Publication date
CA2238814A1 (en) 1997-06-05
US5766869A (en) 1998-06-16
WO1997020066A1 (en) 1997-06-05
AR004826A1 (es) 1999-03-10
ATE254666T1 (de) 2003-12-15
AU1055697A (en) 1997-06-19
EP0873418B1 (en) 2003-11-19
EA000673B1 (ru) 2000-02-28
EA199800493A1 (ru) 1998-12-24
IL124662A (en) 2000-08-13
IL124662A0 (en) 1998-12-06
DE69630808D1 (de) 2003-12-24
EP0873418A1 (en) 1998-10-28
PL327006A1 (en) 1998-11-09

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