MX9803829A - Esteres de acido carboxilico aromatico, la produccion de los mismos y el uso de los mismos como medicamentos. - Google Patents
Esteres de acido carboxilico aromatico, la produccion de los mismos y el uso de los mismos como medicamentos.Info
- Publication number
- MX9803829A MX9803829A MX9803829A MX9803829A MX9803829A MX 9803829 A MX9803829 A MX 9803829A MX 9803829 A MX9803829 A MX 9803829A MX 9803829 A MX9803829 A MX 9803829A MX 9803829 A MX9803829 A MX 9803829A
- Authority
- MX
- Mexico
- Prior art keywords
- same
- alkyl
- stands
- medicaments
- production
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Se describen los compuestos de la formula (Ver Formula) en donde R1 significa hidrogeno o alquilo de 1 a 6 átomos de carbono; R2 significa alquilo de 1 a 6 átomos de carbono o adamantilo; R3 significa alquilo de 1 a 6 átomos de carbono o hidroxilo; o R2 y R3 conjuntamente significan -(CR6R7)N-; R1 significa alquilo de 2 a 9 átomos de carbono, alquenilo de 2 a 8 átomos de carbono, alquinilo de 2 a 8 átomos de carbono, -OCH2R5 o alcanoilo de 2 a 8 átomos de carbono; y si R3 es hidrogeno o hidroxi, R5 significa alquilo de 1 a 6 átomos de carbono, alquenilo de 2 a 6 átomos de carbono o alquinilo de 2 a 8 átomos de carbono; R4 y R7 significan hidrogeno o alquilo de 1 a 6 átomos de carbono; Y significa oxígeno o azufre; y n significa 3, 4 o 5, y las sales farmacéuticamente utilizables de los ácidos carboxílicos de la formula I que actuan como ligandos selectivos de los y-receptores del ácido retinoico, y pueden ser utilizados para el tratamiento de lesiones epiteliales.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH324995 | 1995-11-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
MX9803829A true MX9803829A (es) | 1998-09-30 |
Family
ID=4251881
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX9803829A MX9803829A (es) | 1995-11-16 | 1998-05-14 | Esteres de acido carboxilico aromatico, la produccion de los mismos y el uso de los mismos como medicamentos. |
Country Status (16)
Country | Link |
---|---|
US (2) | US5726191A (es) |
EP (1) | EP0862554B1 (es) |
JP (1) | JP3061865B2 (es) |
KR (1) | KR100286190B1 (es) |
CN (1) | CN1137883C (es) |
AT (1) | ATE280159T1 (es) |
AU (1) | AU705849B2 (es) |
BR (1) | BR9611525A (es) |
CA (1) | CA2237313C (es) |
DE (1) | DE59611123D1 (es) |
DK (1) | DK0862554T3 (es) |
ES (1) | ES2230568T3 (es) |
MX (1) | MX9803829A (es) |
PT (1) | PT862554E (es) |
TR (1) | TR199800870T2 (es) |
WO (1) | WO1997018192A1 (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JO2178B1 (en) * | 1999-10-19 | 2003-04-23 | اف . هوفمان لاروش ايه جي | Treatment of invasive diseases, using selected anti-PAR materials |
DK1351685T3 (da) * | 2001-01-19 | 2008-04-28 | Johnson & Johnson Consumer | Stabiliserede formuleringer af selektive ligander af retinoinsyre-gamma-receptorer |
EP1930005A1 (en) | 2001-01-19 | 2008-06-11 | Johnson and Johnson Consumer Companies, Inc. | Stabilized formulation of selective ligands of retinoic acid gamma-receptors |
US20030166732A1 (en) * | 2002-02-27 | 2003-09-04 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Ambroxol for the treatment of painful conditions in the mouth and pharyngeal cavity |
US20060189893A1 (en) * | 2005-01-06 | 2006-08-24 | Diamics, Inc. | Systems and methods for detecting abnormal cells |
US20060161076A1 (en) * | 2005-01-06 | 2006-07-20 | Diamics, Inc. | Systems and methods for collection of cell clusters |
PL2613776T3 (pl) | 2010-09-01 | 2021-01-11 | Thomas Jefferson University | Kompozycja oraz sposób naprawy i regeneracji mięśni |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3860716A (en) * | 1971-04-06 | 1975-01-14 | Smithkline Corp | Methods and pharmaceutical compositions for inhibiting gluconeogenesis |
DK158947C (da) * | 1982-07-06 | 1991-01-21 | Hoffmann La Roche | Tetrahydronaphthalin-,benzofuran- og benzothiophenderivater, fremstilling og anvendelse deraf samt rodenticid indeholdende saadanne derivater |
US4567184A (en) * | 1982-12-01 | 1986-01-28 | Usv Pharmaceutical Corporation | Certain aryl or hetero-aryl derivatives of 1-hydroxy-pentane or 1-hydroxy-hexane which are useful for treating inflammation and allergies |
EP0170105B1 (en) * | 1984-07-07 | 1990-10-17 | Koichi Prof. Dr. Shudo | Benzoic acid derivatives |
FR2649977B1 (fr) * | 1989-07-18 | 1991-10-04 | Cird | Esters bi-aromatiques, leur procede de preparation et leur utilisation en medecine humaine ou veterinaire et en cosmetique |
CA2119571A1 (en) * | 1991-09-24 | 1993-04-01 | Reinhard Sarges | Retinoids and their use in treating skin diseases and leukemia |
EP0617020A1 (en) * | 1992-04-02 | 1994-09-28 | Shudo, Koichi, Prof. Dr. | Carboxylic acid derivatives having retinoic acid-like activity |
AU691477B2 (en) * | 1992-04-22 | 1998-05-21 | Eisai R&D Management Co., Ltd. | Compounds having selectivity for retinoid X receptors |
-
1996
- 1996-10-23 US US08/735,941 patent/US5726191A/en not_active Expired - Fee Related
- 1996-11-05 DE DE59611123T patent/DE59611123D1/de not_active Expired - Fee Related
- 1996-11-05 WO PCT/CH1996/000390 patent/WO1997018192A1/de active IP Right Grant
- 1996-11-05 CA CA002237313A patent/CA2237313C/en not_active Expired - Fee Related
- 1996-11-05 TR TR1998/00870T patent/TR199800870T2/xx unknown
- 1996-11-05 CN CNB961982519A patent/CN1137883C/zh not_active Expired - Fee Related
- 1996-11-05 JP JP9518467A patent/JP3061865B2/ja not_active Expired - Fee Related
- 1996-11-05 ES ES96934302T patent/ES2230568T3/es not_active Expired - Lifetime
- 1996-11-05 EP EP96934302A patent/EP0862554B1/de not_active Expired - Lifetime
- 1996-11-05 AT AT96934302T patent/ATE280159T1/de not_active IP Right Cessation
- 1996-11-05 PT PT96934302T patent/PT862554E/pt unknown
- 1996-11-05 DK DK96934302T patent/DK0862554T3/da active
- 1996-11-05 BR BR9611525A patent/BR9611525A/pt not_active IP Right Cessation
- 1996-11-05 KR KR1019980703673A patent/KR100286190B1/ko not_active IP Right Cessation
- 1996-11-05 AU AU72759/96A patent/AU705849B2/en not_active Ceased
-
1998
- 1998-01-15 US US09/007,613 patent/US5958956A/en not_active Expired - Fee Related
- 1998-05-14 MX MX9803829A patent/MX9803829A/es unknown
Also Published As
Publication number | Publication date |
---|---|
EP0862554A1 (de) | 1998-09-09 |
BR9611525A (pt) | 1999-07-13 |
JPH11500452A (ja) | 1999-01-12 |
CN1137883C (zh) | 2004-02-11 |
DE59611123D1 (de) | 2004-11-25 |
EP0862554B1 (de) | 2004-10-20 |
PT862554E (pt) | 2005-01-31 |
AU7275996A (en) | 1997-06-05 |
ES2230568T3 (es) | 2005-05-01 |
KR100286190B1 (ko) | 2001-04-16 |
US5726191A (en) | 1998-03-10 |
CN1202154A (zh) | 1998-12-16 |
AU705849B2 (en) | 1999-06-03 |
KR19990067645A (ko) | 1999-08-25 |
CA2237313C (en) | 2006-04-25 |
TR199800870T2 (xx) | 1998-07-21 |
WO1997018192A1 (de) | 1997-05-22 |
ATE280159T1 (de) | 2004-11-15 |
DK0862554T3 (da) | 2005-02-14 |
US5958956A (en) | 1999-09-28 |
CA2237313A1 (en) | 1997-05-22 |
JP3061865B2 (ja) | 2000-07-10 |
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