MX9801056A - Analisis de un fluido biologico usando la deteccion de resultados en intervalos aislados. - Google Patents

Analisis de un fluido biologico usando la deteccion de resultados en intervalos aislados.

Info

Publication number
MX9801056A
MX9801056A MX9801056A MX9801056A MX9801056A MX 9801056 A MX9801056 A MX 9801056A MX 9801056 A MX9801056 A MX 9801056A MX 9801056 A MX9801056 A MX 9801056A MX 9801056 A MX9801056 A MX 9801056A
Authority
MX
Mexico
Prior art keywords
data
calibration
outliers
biological fluid
remove
Prior art date
Application number
MX9801056A
Other languages
English (en)
Other versions
MXPA98001056A (es
Inventor
John F Price
James R Long
Original Assignee
Boehringer Mannheim Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/587,017 external-priority patent/US5606164A/en
Application filed by Boehringer Mannheim Corp filed Critical Boehringer Mannheim Corp
Publication of MX9801056A publication Critical patent/MX9801056A/es
Publication of MXPA98001056A publication Critical patent/MXPA98001056A/es

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/27Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration
    • G01N21/274Calibration, base line adjustment, drift correction
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/35Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
    • G01N21/359Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light using near infrared light
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28Investigating the spectrum
    • G01J2003/2866Markers; Calibrating of scan

Landscapes

  • Physics & Mathematics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Theoretical Computer Science (AREA)
  • Engineering & Computer Science (AREA)
  • Mathematical Physics (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)

Abstract

Un método y un aparato se revela para medir la concentracion de un analito presente en un fluido biologico. El método incluye los pasos de aplicar radiacion NIR a muestras de calibracion para producir datos de calibracion, analizar los datos de calibracion para identificar y eliminar resultados aislados, construir un modelo de calibracion, colectar y analizar muestras desconocidas para identificar y eliminar resultados aislados, y predecir la concentracion del analito de resultados no aislados con el modelo de calibracion. El análisis de los datos de calibracion incluye pretratamiento de datos, descomposicion de datos para eliminar datos redundantes, identificacion y eliminacion de resultados aislados usando intervalos generalizados. El aparato (100) incluye una bomba (102) que circula una muestra a través de un tubo (104) para llenar un flujo de células (106). La luz de una fuente NIR (114) se sincroniza con un detector (110), facilita las mediciones de luz y obscuridad, y pasa a través de un monocrometro (120) y el flujo de células (106) y recto al detector (110), donde la radiacion transmitida a través de la muestra se mide.
MXPA/A/1998/001056A 1995-08-07 1998-02-06 Analisis de un fluido biologico usando la deteccion de resultados en intervalos aislados MXPA98001056A (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US195095P 1995-08-07 1995-08-07
US60/001,950 1995-08-07
US08/587,017 US5606164A (en) 1996-01-16 1996-01-16 Method and apparatus for biological fluid analyte concentration measurement using generalized distance outlier detection
US08587017 1996-01-16
PCT/US1996/012625 WO1997006418A1 (en) 1995-08-07 1996-08-02 Biological fluid analysis using distance outlier detection

Publications (2)

Publication Number Publication Date
MX9801056A true MX9801056A (es) 1998-05-31
MXPA98001056A MXPA98001056A (es) 1998-10-23

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Also Published As

Publication number Publication date
JP3323512B2 (ja) 2002-09-09
AU711324B2 (en) 1999-10-14
WO1997006418A1 (en) 1997-02-20
CA2228844A1 (en) 1997-02-20
EP0846253A4 (en) 2009-11-11
AU6644896A (en) 1997-03-05
JPH11510604A (ja) 1999-09-14
EP0846253A1 (en) 1998-06-10
CA2228844C (en) 2006-03-14

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