MX9703970A - Quimiocinas expresadas, su produccion y usos. - Google Patents

Quimiocinas expresadas, su produccion y usos.

Info

Publication number
MX9703970A
MX9703970A MX9703970A MX9703970A MX9703970A MX 9703970 A MX9703970 A MX 9703970A MX 9703970 A MX9703970 A MX 9703970A MX 9703970 A MX9703970 A MX 9703970A MX 9703970 A MX9703970 A MX 9703970A
Authority
MX
Mexico
Prior art keywords
ecs
antibodies capable
binding specifically
production
nucleic acid
Prior art date
Application number
MX9703970A
Other languages
English (en)
Other versions
MXPA97003970A (es
Inventor
Craig G Wilde
Phillip R Hawkins
Olga Bandman
Jeffrey J Seilhamer
Kuldeep Singh Neote
Original Assignee
Incyte Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Pharma Inc filed Critical Incyte Pharma Inc
Publication of MX9703970A publication Critical patent/MX9703970A/es
Publication of MXPA97003970A publication Critical patent/MXPA97003970A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/521—Chemokines
    • C07K14/523—Beta-chemokines, e.g. RANTES, I-309/TCA-3, MIP-1alpha, MIP-1beta/ACT-2/LD78/SCIF, MCP-1/MCAF, MCP-2, MCP-3, LDCF-1, LDCF-2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/14—Lymphokine; related peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La presente invencion provee secuencias de nucleotido y de aminoácido que identifican y codifican quimiocinas expresadas novedosas (ECs) de tejidos de hígado y de la glándula pituitaria. La presente invencion también provee moléculas antisentido a las secuencias de un nucleotido, que codifican ECs, vectores de expresion para la produccion de ECs purificadas, anticuerpos capaces de unirse específicamente a ECs, sondas de hibridacion u oligonucleotidos para la deteccion de secuencias diseñadas de nucleotido que codifican EC, células huésped genéticamente diseñadas a través de ingeniería para la expresion de ECs, pruebas de diagnostico para inflamacion o enfermedad con base en las moléculas de ácido nucleico que codifican EC o anticuerpos capaces de unirse específicamente a ECs, composiciones farmacéuticas para el tratamiento de inflamacion o enfermedad con base en las moléculas de ácido nucleico que codifican EC o anticuerpos capaces de unirse específicamente a ECs.
MXPA/A/1997/003970A 1994-11-29 1997-05-29 Quimiocinas expresadas, su produccion y usos MXPA97003970A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/347,492 US5602008A (en) 1994-11-29 1994-11-29 DNA encoding a liver expressed chemokine
US08347492 1994-11-29
PCT/US1995/015484 WO1996016979A1 (en) 1994-11-29 1995-11-29 Expressed chemokines, their production and uses

Publications (2)

Publication Number Publication Date
MX9703970A true MX9703970A (es) 1997-09-30
MXPA97003970A MXPA97003970A (es) 1998-07-03

Family

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Also Published As

Publication number Publication date
CA2206113A1 (en) 1996-06-06
JPH10510430A (ja) 1998-10-13
EP0793672A1 (en) 1997-09-10
WO1996016979A1 (en) 1996-06-06
US5602008A (en) 1997-02-11
US20030083468A1 (en) 2003-05-01
EP0793672A4 (en) 1998-08-19
US5936068A (en) 1999-08-10
AU4504696A (en) 1996-06-19

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