MX9701992A - Procedimiento para preparar compuestos de trans-3-fenilglicidamida opticamente activos. - Google Patents

Procedimiento para preparar compuestos de trans-3-fenilglicidamida opticamente activos.

Info

Publication number
MX9701992A
MX9701992A MX9701992A MX9701992A MX9701992A MX 9701992 A MX9701992 A MX 9701992A MX 9701992 A MX9701992 A MX 9701992A MX 9701992 A MX9701992 A MX 9701992A MX 9701992 A MX9701992 A MX 9701992A
Authority
MX
Mexico
Prior art keywords
phenylglycidamide
optionally active
prepare
compounds
active trans
Prior art date
Application number
MX9701992A
Other languages
English (en)
Other versions
MXPA97001992A (es
Inventor
Hiroaki Matsumae
Akiko Idei
Takuo Nishida
Yasuhiko Ozaki
Takeji Shibatani
Original Assignee
Tanabe Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co filed Critical Tanabe Seiyaku Co
Publication of MX9701992A publication Critical patent/MX9701992A/es
Publication of MXPA97001992A publication Critical patent/MXPA97001992A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Se describe un procedimiento para preparar un compuesto de trans-3-fenilglicidamidaopticamente activo, que comprende someter un compuesto de trans-3-fenilglicidamida racémico de la formula (I): en donde el anillo A es benceno substituido o no substituido, y R1 es H o alquilo inferior, para resolucion optica usando un microorganismo que tiene la capacidad de hidrolizar de preferencia un isomero de (2S, 3R) o un isomero de (2R, 3S) del mismo, y un procedimiento para preparar un derivado de 1,5-benzotiazepina opticamente activo a partir del compuesto de trans-3-fenilglicidamida opticamente activo así obtenido.
MXPA/A/1997/001992A 1996-03-15 1997-03-14 Procedimiento para preparar compuestos de trans-3-fenilglicidamida opticamente activos MXPA97001992A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP8-58992 1996-03-15
JP5899296 1996-03-15
JP58992/1996 1996-03-15

Publications (2)

Publication Number Publication Date
MX9701992A true MX9701992A (es) 1998-06-28
MXPA97001992A MXPA97001992A (es) 1998-10-30

Family

ID=

Also Published As

Publication number Publication date
US5883264A (en) 1999-03-16
SG72731A1 (en) 2000-05-23
ID16242A (id) 1997-09-11
EP0795609A2 (en) 1997-09-17
EP0795609A3 (en) 1999-02-17
CA2199880A1 (en) 1997-09-15
KR970065531A (ko) 1997-10-13

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