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Application filed by Novartis Ag Tambien Denominada, Y O Novartis IncfiledCriticalNovartis Ag Tambien Denominada
Priority claimed from PCT/EP1995/002720external-prioritypatent/WO1996003425A1/en
Publication of MXPA97000658ApublicationCriticalpatent/MXPA97000658A/en
Publication of MX9700658ApublicationCriticalpatent/MX9700658A/en
Medicines That Contain Protein Lipid Enzymes And Other Medicines
(AREA)
Preparation Of Compounds By Using Micro-Organisms
(AREA)
Peptides Or Proteins
(AREA)
Abstract
The invention relates to a process for the preparation of a biologically active and correctly folded protein in the presence of a denaturing agent like urea or guanidine hydrochloride and the separation of the correctly folded protein therefrom directly. This process can be applied, for example, in the renaturation of recombinant proteins like hirudin or epidermal growth factor.
MX9700658A1995-07-121995-07-12Process for folding of proteins like recombinant hirudin or epidermal growth factor.
MX9700658A
(en)