Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Corning Diagnostics CorpfiledCriticalCiba Corning Diagnostics Corp
Priority claimed from PCT/IB1995/000226external-prioritypatent/WO1995027078A1/en
Publication of MXPA96004607ApublicationCriticalpatent/MXPA96004607A/en
Publication of MX9604607ApublicationCriticalpatent/MX9604607A/en
Measuring Or Testing Involving Enzymes Or Micro-Organisms
(AREA)
Abstract
A new method has been developed for conducting a gene probe assay. The preferred technique involves (1) using a gene amplification technique (e.g., PCR) to multiply the gene sequence of interest and (2) using a hybridization-ligation detection methodology, wherein the sequences of probes hybridized to the target sequence allow for separation and detection (e.g., probes might contain a combination of magnetic particles and acridinium esters) to determine if a specific sequence is present,
MX9604607A1995-04-031995-04-03Hibridization-ligation assays for the detection of specific nucleic acid sequences.
MX9604607A
(en)