MX9604182A - Vaccines against helminthic parasites. - Google Patents
Vaccines against helminthic parasites.Info
- Publication number
- MX9604182A MX9604182A MX9604182A MX9604182A MX9604182A MX 9604182 A MX9604182 A MX 9604182A MX 9604182 A MX9604182 A MX 9604182A MX 9604182 A MX9604182 A MX 9604182A MX 9604182 A MX9604182 A MX 9604182A
- Authority
- MX
- Mexico
- Prior art keywords
- parasite
- vaccines against
- native
- helminthic parasites
- helminths
- Prior art date
Links
- 244000045947 parasite Species 0.000 title abstract 3
- 229960005486 vaccine Drugs 0.000 title abstract 2
- 244000000013 helminth Species 0.000 abstract 3
- 102000018697 Membrane Proteins Human genes 0.000 abstract 1
- 108010052285 Membrane Proteins Proteins 0.000 abstract 1
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 230000000890 antigenic effect Effects 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 230000004807 localization Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000002243 precursor Substances 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
- 125000003396 thiol group Chemical class [H]S* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6402—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from non-mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43536—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from worms
- C07K14/4354—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from worms from nematodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
The present invention provides a protective helminth parasite antigen obtainable from adult helminths characterised by: (i) in native form being an integral membrane protein; (ii) having a native localisation in the parasite gut; (iii) being capable of binding to a thiol affinity medium; and (iv) being recognised by sera from immunised animal hosts, containing antibodies capable of inhibiting parasite growth and/or development, or a functionally-equivalent variant, or antigenic fragment or precursor thereof, its preparation from adult helminths, its use in vaccine compositions, DNA sequences encoding it and its production by recombinant means.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9405990A GB9405990D0 (en) | 1994-03-25 | 1994-03-25 | Vaccines |
GB9405925A GB9405925D0 (en) | 1994-03-25 | 1994-03-25 | Vaccines |
PCT/GB1995/000665 WO1995026402A1 (en) | 1994-03-25 | 1995-03-24 | Vaccines against helminthic parasites |
Publications (1)
Publication Number | Publication Date |
---|---|
MX9604182A true MX9604182A (en) | 1997-12-31 |
Family
ID=26304584
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX9604182A MX9604182A (en) | 1994-03-25 | 1995-03-24 | Vaccines against helminthic parasites. |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0804570A1 (en) |
AU (1) | AU701642B2 (en) |
CA (1) | CA2182178A1 (en) |
MX (1) | MX9604182A (en) |
WO (1) | WO1995026402A1 (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6017757A (en) * | 1997-02-20 | 2000-01-25 | Mississippi State University | Isolated viable nematode intestinal cells |
KR100900837B1 (en) | 2007-12-07 | 2009-06-04 | (주)두비엘 | A powerful vaccine composition comprising lipopeptide and poly(i:c) as an adjuvant |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZW8893A1 (en) * | 1992-07-21 | 1994-06-01 | Pitman Moore Inc | Vaccines |
-
1995
- 1995-03-24 EP EP95912351A patent/EP0804570A1/en not_active Withdrawn
- 1995-03-24 AU AU19564/95A patent/AU701642B2/en not_active Ceased
- 1995-03-24 WO PCT/GB1995/000665 patent/WO1995026402A1/en active Application Filing
- 1995-03-24 MX MX9604182A patent/MX9604182A/en unknown
- 1995-03-24 CA CA002182178A patent/CA2182178A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CA2182178A1 (en) | 1995-10-05 |
AU1956495A (en) | 1995-10-17 |
AU701642B2 (en) | 1999-02-04 |
EP0804570A1 (en) | 1997-11-05 |
WO1995026402A1 (en) | 1995-10-05 |
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