MX9603868A - Pharmaceutical composition of indene derivatives for regulating apoptosis. - Google Patents

Pharmaceutical composition of indene derivatives for regulating apoptosis.

Info

Publication number
MX9603868A
MX9603868A MX9603868A MX9603868A MX9603868A MX 9603868 A MX9603868 A MX 9603868A MX 9603868 A MX9603868 A MX 9603868A MX 9603868 A MX9603868 A MX 9603868A MX 9603868 A MX9603868 A MX 9603868A
Authority
MX
Mexico
Prior art keywords
pharmaceutical composition
regulating apoptosis
indene derivatives
present
group
Prior art date
Application number
MX9603868A
Other languages
Spanish (es)
Inventor
Tetsuro Kikuchi
Katsura Tottori
Yasufumi Uwahodo
Hideo Tanaka
Hiroyuki Ichikawa
Yukihisa Ono
Satoru Nakai
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of MX9603868A publication Critical patent/MX9603868A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention provides a pharmaceutical composition for regulating apoptosis containing at least one active ingredient selected from the group consisting of 2,3-dihydro-1H-indene derivatives represented by general formula (I), (wherein R1, R2, R3 and R4 are each the same or different and are lower alkyl groups; R5 is a lower alkoxy group; and <u>A</u> is a lower alkylene group) and salts thereof. The present invention also provides methods for treating and preventing various diseases by regulating apoptosis by use of said pharmaceutical composition.
MX9603868A 1995-01-11 1995-12-15 Pharmaceutical composition of indene derivatives for regulating apoptosis. MX9603868A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP249095 1995-01-11
PCT/JP1995/002578 WO1996021449A1 (en) 1995-01-11 1995-12-15 Pharmaceutical composition of indene derivatives for regulating apoptosis

Publications (1)

Publication Number Publication Date
MX9603868A true MX9603868A (en) 1997-03-29

Family

ID=11530812

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9603868A MX9603868A (en) 1995-01-11 1995-12-15 Pharmaceutical composition of indene derivatives for regulating apoptosis.

Country Status (7)

Country Link
EP (1) EP0749311A1 (en)
CN (1) CN1143322A (en)
AR (1) AR001786A1 (en)
AU (1) AU4188896A (en)
CA (1) CA2185246A1 (en)
MX (1) MX9603868A (en)
WO (1) WO1996021449A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2763847B1 (en) 1997-05-28 2003-06-06 Sanofi Sa USE OF 4-SUBSTITUTED TETRAHYDROPYRIDINES FOR MANUFACTURING TGF-BETA-1 MEDICAMENTS

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03112928A (en) * 1989-09-25 1991-05-14 Otsuka Pharmaceut Co Ltd Pharmaceutical composition improved in absorbability
AU648690B2 (en) * 1991-07-03 1994-04-28 Otsuka Pharmaceutical Co., Ltd. Apoptosis regulator

Also Published As

Publication number Publication date
AR001786A1 (en) 1997-12-10
AU4188896A (en) 1996-07-31
EP0749311A1 (en) 1996-12-27
CA2185246A1 (en) 1996-07-18
CN1143322A (en) 1997-02-19
WO1996021449A1 (en) 1996-07-18

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