CA2198266A1 - Novel benzimidazole derivatives - Google Patents
Novel benzimidazole derivativesInfo
- Publication number
- CA2198266A1 CA2198266A1 CA002198266A CA2198266A CA2198266A1 CA 2198266 A1 CA2198266 A1 CA 2198266A1 CA 002198266 A CA002198266 A CA 002198266A CA 2198266 A CA2198266 A CA 2198266A CA 2198266 A1 CA2198266 A1 CA 2198266A1
- Authority
- CA
- Canada
- Prior art keywords
- group
- benzimidazole derivatives
- salts
- quinolinonyl
- novel benzimidazole
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229940058303 antinematodal benzimidazole derivative Drugs 0.000 title abstract 3
- 125000003785 benzimidazolyl group Chemical class N1=C(NC2=C1C=CC=C2)* 0.000 title abstract 3
- -1 3,4dihydro-2(1H)-quinolinonyl group Chemical group 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000005955 1H-indazolyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000003387 indolinyl group Chemical group N1(CCC2=CC=CC=C12)* 0.000 abstract 1
- 125000001041 indolyl group Chemical group 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
The present invention provides novel benzimidazole derivatives or salts thereof represented by general formula (1), wherein R t is a hydrogen atom or a halogen atom R2 is a phenyl-lower alkyl group; R3 is a heterocyclic group selected from the group consisting of an indolyl group, indolinyl group, 1H-indazolyl group, 2(1H)-quinolinonyl group, 3,4dihydro-2(1H)-quinolinonyl group and 1,4-benzoxazinyl group; A is a lower alkylene group; n is 0 or 1. The benzimidazole derivatives or salts of the present invention are effective agents for treating various arteriosclerotic diseases.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP17180795 | 1995-07-07 | ||
| JP7/171807 | 1995-07-07 | ||
| PCT/JP1996/001841 WO1997003070A1 (en) | 1995-07-07 | 1996-07-03 | Novel benzimidazole derivatives having cgmp-phosphodisterase inhibiting activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2198266A1 true CA2198266A1 (en) | 1997-01-30 |
| CA2198266C CA2198266C (en) | 2006-04-04 |
Family
ID=36143252
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002198266A Expired - Fee Related CA2198266C (en) | 1995-07-07 | 1996-07-03 | Novel benzimidazole derivatives |
Country Status (1)
| Country | Link |
|---|---|
| CA (1) | CA2198266C (en) |
-
1996
- 1996-07-03 CA CA002198266A patent/CA2198266C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2198266C (en) | 2006-04-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |