MX9601378A - Adyuvante de quillaja saponaria y formulacion de vacuna que contiene la misma. - Google Patents

Adyuvante de quillaja saponaria y formulacion de vacuna que contiene la misma.

Info

Publication number
MX9601378A
MX9601378A MX9601378A MX9601378A MX9601378A MX 9601378 A MX9601378 A MX 9601378A MX 9601378 A MX9601378 A MX 9601378A MX 9601378 A MX9601378 A MX 9601378A MX 9601378 A MX9601378 A MX 9601378A
Authority
MX
Mexico
Prior art keywords
adjuvant
quillaja saponaria
saponaria molina
vaccine composition
saponin component
Prior art date
Application number
MX9601378A
Other languages
English (en)
Inventor
Hong-Seob So
Hye-Sung Yoon
Young-Sun Kwon
Joong-Myung Cho
Deog-Young Choi
Wang-Sik Lyu
Original Assignee
Lg Chemical Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lg Chemical Ltd filed Critical Lg Chemical Ltd
Publication of MX9601378A publication Critical patent/MX9601378A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55577—Saponins; Quil A; QS21; ISCOMS

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

Un componente de saponina novedoso que tiene un peso molecular de aproximadamente 956 daltones, un procedimiento para aislar el componente de saponina a partir de la corteza de Quillaja saponaria Molina, una formulacion de vacuna que comprende el componente de saponina como un adyuvante inmune, un método para aumentar la respuesta a un antígeno empleando una composicion adyuvante que comprende el componente de saponina y un segundo adyuvante.
MX9601378A 1995-04-13 1996-04-12 Adyuvante de quillaja saponaria y formulacion de vacuna que contiene la misma. MX9601378A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR19950008590 1995-04-13
KR19950008589 1995-04-13

Publications (1)

Publication Number Publication Date
MX9601378A true MX9601378A (es) 1997-04-30

Family

ID=37027969

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9601378A MX9601378A (es) 1995-04-13 1996-04-12 Adyuvante de quillaja saponaria y formulacion de vacuna que contiene la misma.

Country Status (16)

Country Link
US (1) US5817314A (es)
EP (1) EP0765333B1 (es)
JP (1) JP2761809B2 (es)
KR (1) KR0184779B1 (es)
CN (2) CN1044478C (es)
AR (1) AR001618A1 (es)
AT (1) ATE186541T1 (es)
AU (1) AU678941B2 (es)
BR (1) BR9606311A (es)
CA (1) CA2190344C (es)
DE (1) DE69605094T2 (es)
DK (1) DK0765333T3 (es)
ES (1) ES2140837T3 (es)
MX (1) MX9601378A (es)
TW (1) TW442293B (es)
WO (1) WO1996032401A1 (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6080725A (en) * 1997-05-20 2000-06-27 Galenica Pharmaceuticals, Inc. Immunostimulating and vaccine compositions employing saponin analog adjuvants and uses thereof
US6645495B1 (en) * 1997-08-29 2003-11-11 Antigenics, Inc. Compositions of saponin adjuvants and excipients
AU5565599A (en) 1998-08-14 2000-03-06 Dante J. Marciani Chemically modified saponins and the use thereof as adjuvants
TW586935B (en) * 1998-09-14 2004-05-11 Kitasato Inst Saponin-containing vaccine preparation
CA2347099C (en) * 1998-10-16 2014-08-05 Smithkline Beecham Biologicals S.A. Adjuvant systems comprising an immunostimulant adsorbed to a metallic salt particle and vaccines thereof
AU2243801A (en) * 1999-12-08 2001-06-18 Statens Veterinarmedicinska Anstalt Vaccine adjuvants comprising ginseng plant extract and added aluminium salt
US6905712B2 (en) * 1999-12-08 2005-06-14 Statens Veterinarmedicinska Anstalt Vaccine adjuvants comprising ginseng plant extract and added aluminum salt
US8883170B2 (en) * 2008-09-03 2014-11-11 Western Illinois University Research Foundation Adjuvant
EP2359702B1 (en) 2010-01-22 2014-06-04 Symrise AG Solubilization agent for solubilizing polyphenols, flavonoids and/or diterpenoid glucosides
EP2359698B1 (en) 2010-01-22 2013-12-04 Symrise AG Compositions with a surfactant system comprising saponins, and lecithin
US10064881B2 (en) 2010-12-09 2018-09-04 Y&B Mother's Choice Ltd. Natural formulations
DK2648742T3 (da) 2010-12-09 2019-07-15 Y&B Mothers Choice Ltd Formuleringer indeholdende saponiner og anvendelser deraf
US10434058B2 (en) 2010-12-09 2019-10-08 Y&B Mother's Choice Ltd. Natural formulations
EP2628398B1 (de) 2012-02-19 2016-09-07 Symrise AG Stoffgemische
IL229836A0 (en) 2013-12-08 2014-03-31 Y & B Mother S Choice Ltd Formulations to reduce or suppress irritation to eye tissue
CN105213471A (zh) * 2014-05-29 2016-01-06 江口县苗药生物科技有限公司 一种皂树皮总皂苷的提取工艺
CA3083078A1 (en) 2017-12-01 2019-06-06 Glaxosmithkline Biologicals Sa Saponin purification
EP3717005A1 (en) * 2017-12-01 2020-10-07 GlaxoSmithKline Biologicals S.A. Saponin extraction
TWI820099B (zh) * 2018-03-28 2023-11-01 台灣浩鼎生技股份有限公司 新穎皂素佐劑及其評估方法
CN116355035B (zh) * 2021-12-28 2024-03-12 成都迈科康生物科技有限公司 一种qs21免疫佐剂的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5057540A (en) * 1987-05-29 1991-10-15 Cambridge Biotech Corporation Saponin adjuvant
WO1994022476A1 (en) * 1993-03-29 1994-10-13 Pfizer Inc. Multicomponent clostridial vaccines using saponin adjuvants

Also Published As

Publication number Publication date
JP2761809B2 (ja) 1998-06-04
ES2140837T3 (es) 2000-03-01
ATE186541T1 (de) 1999-11-15
CA2190344A1 (en) 1996-10-16
AR001618A1 (es) 1997-11-26
CN1044478C (zh) 1999-08-04
DK0765333T3 (da) 2000-03-13
EP0765333B1 (en) 1999-11-10
CN1149875A (zh) 1997-05-14
CN1262958A (zh) 2000-08-16
DE69605094T2 (de) 2000-07-06
JPH09510740A (ja) 1997-10-28
BR9606311A (pt) 1997-09-16
DE69605094D1 (de) 1999-12-16
AU678941B2 (en) 1997-06-12
TW442293B (en) 2001-06-23
WO1996032401A1 (en) 1996-10-17
KR960037694A (ko) 1996-11-19
US5817314A (en) 1998-10-06
EP0765333A1 (en) 1997-04-02
KR0184779B1 (ko) 1999-04-01
CA2190344C (en) 2001-04-10
AU5290096A (en) 1996-10-30

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