MX9301512A - PROCESS FOR THE PREPARATION OF RUFLOXACIN AND SALTS OF THE SAME. - Google Patents
PROCESS FOR THE PREPARATION OF RUFLOXACIN AND SALTS OF THE SAME.Info
- Publication number
- MX9301512A MX9301512A MX9301512A MX9301512A MX9301512A MX 9301512 A MX9301512 A MX 9301512A MX 9301512 A MX9301512 A MX 9301512A MX 9301512 A MX9301512 A MX 9301512A MX 9301512 A MX9301512 A MX 9301512A
- Authority
- MX
- Mexico
- Prior art keywords
- rufloxacin
- formula
- salts
- preparation
- same
- Prior art date
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
El rufloxacin se prepara reduciendo un disulfuro de quinolona de la fórmula (II) ver formula (2). Sometiendo la 2-mercaptometil quinolona obtenida de esta manera de la fórmula (III) ver la figura (3). A una ciclización en un medio base e hidrolizado el éster de rufloxacin obtenido de esta manera, para aislar rufloxacin. Un nuevo método de hidrolizar el éster de rufloxacin para dar rufloxacin y sus sales farmacéuticamente aceptables, también se describe.Rufloxacin is prepared by reducing a quinolone disulfide of formula (II) see formula (2). Submitting the 2-mercaptomethyl quinolone thus obtained from formula (III) see figure (3). Upon cyclization in a base medium and hydrolyzed the rufloxacin ester thus obtained, to isolate rufloxacin. A new method of hydrolyzing the rufloxacin ester to give rufloxacin and its pharmaceutically acceptable salts, is also described.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT000630A ITMI920630A1 (en) | 1992-03-18 | 1992-03-18 | QUINOLONIC DISULFIDE |
Publications (1)
Publication Number | Publication Date |
---|---|
MX9301512A true MX9301512A (en) | 1993-11-01 |
Family
ID=11362488
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX9301512A MX9301512A (en) | 1992-03-18 | 1993-03-18 | PROCESS FOR THE PREPARATION OF RUFLOXACIN AND SALTS OF THE SAME. |
MX9301513A MX9301513A (en) | 1992-03-18 | 1993-03-18 | QUINOLONE DISULFIDE. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX9301513A MX9301513A (en) | 1992-03-18 | 1993-03-18 | QUINOLONE DISULFIDE. |
Country Status (3)
Country | Link |
---|---|
IL (2) | IL105076A0 (en) |
IT (1) | ITMI920630A1 (en) |
MX (2) | MX9301512A (en) |
-
1992
- 1992-03-18 IT IT000630A patent/ITMI920630A1/en not_active IP Right Cessation
-
1993
- 1993-03-16 IL IL105076A patent/IL105076A0/en unknown
- 1993-03-16 IL IL105075A patent/IL105075A0/en unknown
- 1993-03-18 MX MX9301512A patent/MX9301512A/en unknown
- 1993-03-18 MX MX9301513A patent/MX9301513A/en unknown
Also Published As
Publication number | Publication date |
---|---|
MX9301513A (en) | 1993-11-01 |
IL105076A0 (en) | 1993-07-08 |
IL105075A0 (en) | 1993-07-08 |
ITMI920630A0 (en) | 1992-03-18 |
ITMI920630A1 (en) | 1993-09-19 |
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