MX9300787A - Peptido para diagnosticar e inmunizar contra la infeccion por t. cruzi. - Google Patents
Peptido para diagnosticar e inmunizar contra la infeccion por t. cruzi.Info
- Publication number
- MX9300787A MX9300787A MX9300787A MX9300787A MX9300787A MX 9300787 A MX9300787 A MX 9300787A MX 9300787 A MX9300787 A MX 9300787A MX 9300787 A MX9300787 A MX 9300787A MX 9300787 A MX9300787 A MX 9300787A
- Authority
- MX
- Mexico
- Prior art keywords
- peptide
- ala glu
- diagnose
- pro lys
- glu pro
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 4
- 208000015181 infectious disease Diseases 0.000 title abstract 2
- 206010001935 American trypanosomiasis Diseases 0.000 abstract 4
- 241000223109 Trypanosoma cruzi Species 0.000 abstract 4
- VBRDBGCROKWTPV-XHNCKOQMSA-N Ala-Glu-Pro Chemical compound C[C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N1CCC[C@@H]1C(=O)O)N VBRDBGCROKWTPV-XHNCKOQMSA-N 0.000 abstract 2
- 208000024699 Chagas disease Diseases 0.000 abstract 2
- 238000002965 ELISA Methods 0.000 abstract 1
- PNPYKQFJGRFYJE-GUBZILKMSA-N Lys-Ala-Glu Chemical compound [H]N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(O)=O PNPYKQFJGRFYJE-GUBZILKMSA-N 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 230000000890 antigenic effect Effects 0.000 abstract 1
- 230000003053 immunization Effects 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/975—Kit
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Toxicology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Se describe un péptido antigénico, que comprende por lo menos 15 aminoácidos que tienen la secuencia Ala Glu Pro Lys Ala Glu Pro Lys X Ala Glu Pro Lys X en donde X es Pro o Ser. Este péptido es útil en el análisis ELISA para detectar anticuerpos específicos a la infección por T.cruzi y la enfermedad de Chagas. Este péptido es además útil en una composición de vacuna para inmunizar a un individuo para evitar la enfermedad de Chagas por exposición a T.cruzi.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/836,642 US5304371A (en) | 1992-02-14 | 1992-02-14 | Peptide for diagnosing and immunizing against T. cruzi infection |
Publications (1)
Publication Number | Publication Date |
---|---|
MX9300787A true MX9300787A (es) | 1993-11-01 |
Family
ID=25272399
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX9300787A MX9300787A (es) | 1992-02-14 | 1993-02-12 | Peptido para diagnosticar e inmunizar contra la infeccion por t. cruzi. |
Country Status (8)
Country | Link |
---|---|
US (2) | US5304371A (es) |
EP (1) | EP0649475B1 (es) |
BR (1) | BR9305995A (es) |
CA (1) | CA2129747C (es) |
DE (1) | DE69319909D1 (es) |
ES (1) | ES2118939T3 (es) |
MX (1) | MX9300787A (es) |
WO (1) | WO1993016199A1 (es) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5876734A (en) | 1994-03-24 | 1999-03-02 | Kirchhoff; Louis V. | Polypeptides for diagnosing infection with Trypanosoma cruzi |
US5879687A (en) * | 1994-04-22 | 1999-03-09 | Corixa Corporation | Methods for enhancement of protective immune responses |
US6013268A (en) | 1994-04-22 | 2000-01-11 | Corixa Corporation | Methods for enhancement of protective immune responses |
NZ291153A (en) * | 1994-07-25 | 1999-01-28 | Boehringer Mannheim Gmbh | Determination of a specific antibody using multiple antigens containing several epitope regions which react with the antibody |
US5756662A (en) * | 1995-03-14 | 1998-05-26 | Corixa Corporation | Compounds and methods for the detection of T. cruzi infection |
US5912166A (en) * | 1995-04-21 | 1999-06-15 | Corixa Corporation | Compounds and methods for diagnosis of leishmaniasis |
US5916572A (en) * | 1995-11-14 | 1999-06-29 | Corixa Corporation | Compounds and methods for the detection and prevention of T. cruzi infection |
US6228372B1 (en) * | 1997-04-15 | 2001-05-08 | Corixa Corporation | Compounds and methods for the detection and prevention of T. cruzi infection |
US6054135A (en) * | 1996-11-14 | 2000-04-25 | Corixa | Compounds and methods for the detection and prevention of T. cruzi infection |
US6419933B1 (en) | 1995-11-14 | 2002-07-16 | Corixa Corporation | Compounds and methods for the detection and prevention of T.cruzi infection |
WO2000062828A1 (en) * | 1996-04-30 | 2000-10-26 | Medtronic, Inc. | Autologous fibrin sealant and method for making the same |
US6134846A (en) * | 1997-11-18 | 2000-10-24 | Lamb; Charles | Modular slatwall system |
US6875584B1 (en) * | 1999-03-02 | 2005-04-05 | University Of Georgia Research Foundation, Inc. | Prophylactic and therapeutic immunization against protozoan infection and disease |
AR027370A1 (es) * | 2000-02-17 | 2003-03-26 | Lg Chemical Ltd | Inmunoensayo y reactivo de diagnostico para malaria, y correspondientes metodos de preparacion, vectores de expresion y transformantes |
US9028844B2 (en) | 2006-03-17 | 2015-05-12 | Vib Vzw | Vaccine against Trypanosoma cruzi infection |
US7749717B2 (en) * | 2006-10-19 | 2010-07-06 | Abbott Laboratories | Methods for the detection and diagnosis of Trypanosoma cruzi infection |
CN102083853B (zh) | 2008-07-03 | 2014-09-17 | 传染性疾病研究院 | 融合蛋白及其在利什曼病的诊断和治疗中的用途 |
AR128004A1 (es) * | 2021-12-17 | 2024-03-20 | 16 | Péptidos antigénicos y métodos para utilizarlos en el diagnóstico de la enfermedad de chagas |
-
1992
- 1992-02-14 US US07/836,642 patent/US5304371A/en not_active Expired - Lifetime
-
1993
- 1993-02-11 DE DE69319909T patent/DE69319909D1/de not_active Expired - Lifetime
- 1993-02-11 BR BR9305995A patent/BR9305995A/pt not_active Application Discontinuation
- 1993-02-11 ES ES93905886T patent/ES2118939T3/es not_active Expired - Lifetime
- 1993-02-11 CA CA002129747A patent/CA2129747C/en not_active Expired - Lifetime
- 1993-02-11 EP EP93905886A patent/EP0649475B1/en not_active Expired - Lifetime
- 1993-02-11 WO PCT/US1993/001231 patent/WO1993016199A1/en active IP Right Grant
- 1993-02-12 MX MX9300787A patent/MX9300787A/es unknown
- 1993-12-17 US US08/169,563 patent/US5413912A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
BR9305995A (pt) | 1997-03-11 |
EP0649475A1 (en) | 1995-04-26 |
US5413912A (en) | 1995-05-09 |
EP0649475A4 (en) | 1995-12-20 |
ES2118939T3 (es) | 1998-10-01 |
EP0649475B1 (en) | 1998-07-22 |
CA2129747A1 (en) | 1993-08-15 |
CA2129747C (en) | 2001-04-17 |
WO1993016199A1 (en) | 1993-08-19 |
US5304371A (en) | 1994-04-19 |
DE69319909D1 (de) | 1998-08-27 |
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