MX9203692A - THERAPEUTIC PREPARATIONS. - Google Patents

THERAPEUTIC PREPARATIONS.

Info

Publication number
MX9203692A
MX9203692A MX9203692A MX9203692A MX9203692A MX 9203692 A MX9203692 A MX 9203692A MX 9203692 A MX9203692 A MX 9203692A MX 9203692 A MX9203692 A MX 9203692A MX 9203692 A MX9203692 A MX 9203692A
Authority
MX
Mexico
Prior art keywords
quinazoline derivatives
new
trifluoromethyl
nitro
alkyl
Prior art date
Application number
MX9203692A
Other languages
Spanish (es)
Inventor
Andrew John Barker
David Hum Davies
Original Assignee
Ici Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB919113970A external-priority patent/GB9113970D0/en
Priority claimed from GB929201133A external-priority patent/GB9201133D0/en
Priority claimed from GB929213181A external-priority patent/GB9213181D0/en
Application filed by Ici Plc filed Critical Ici Plc
Publication of MX9203692A publication Critical patent/MX9203692A/en

Links

Abstract

La presente invención se refiere a composiciones farmacéuticas que comprenden derivados de quinazolina nuevos o conocidos de la fórmula I: (fórmula); en donde por ejemplo, R1 es hidrógeno, trifluorometilo o nitro, n es 1 y R2 halógeno, trifluorometilo, nitro, ciano, (1-4C) alquilo, (1-4C)alcoxi, N-(1-4C)alquilamino,N,N-di-((1-4C)alquil)amino, (1-4C)alquiltio, (1-4C)alquilsulfinilo o (1-4C) alquilsulfonilo; y diluyentes farmacéuticamente aceptables o portadores de los mismos; los nuevos derivados de quinazolina y a un procedimiento para su preparación; y el uso de las propiedades inhibitorias del receptor quinasa tirosina tanto de los derivados de quinazolina conocidos como de los nuevos en el tratamiento del cáncer.The present invention relates to pharmaceutical compositions comprising new or known quinazoline derivatives of formula I: (formula); where for example, R1 is hydrogen, trifluoromethyl or nitro, n is 1 and R2 is halogen, trifluoromethyl, nitro, cyano, (1-4C) alkyl, (1-4C) alkoxy, N- (1-4C) alkylamino, N , N-di - ((1-4C) alkyl) amino, (1-4C) alkylthio, (1-4C) alkylsulfinyl or (1-4C) alkylsulfonyl; and pharmaceutically acceptable diluents or carriers thereof; the new quinazoline derivatives and a process for their preparation; and the use of the inhibitory properties of the tyrosine receptor kinase of both known and new quinazoline derivatives in the treatment of cancer.

MX9203692A 1991-06-28 1992-06-29 THERAPEUTIC PREPARATIONS. MX9203692A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB919113970A GB9113970D0 (en) 1991-06-28 1991-06-28 Therapeutic preparations
GB929201133A GB9201133D0 (en) 1992-01-20 1992-01-20 Therapeutic preparations
GB929213181A GB9213181D0 (en) 1991-06-28 1992-06-22 Therapeutic agents

Publications (1)

Publication Number Publication Date
MX9203692A true MX9203692A (en) 1994-07-29

Family

ID=27265736

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9203692A MX9203692A (en) 1991-06-28 1992-06-29 THERAPEUTIC PREPARATIONS.

Country Status (1)

Country Link
MX (1) MX9203692A (en)

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Legal Events

Date Code Title Description
FG Grant or registration
MM Annulment or lapse due to non-payment of fees