MX9203692A - THERAPEUTIC PREPARATIONS. - Google Patents
THERAPEUTIC PREPARATIONS.Info
- Publication number
- MX9203692A MX9203692A MX9203692A MX9203692A MX9203692A MX 9203692 A MX9203692 A MX 9203692A MX 9203692 A MX9203692 A MX 9203692A MX 9203692 A MX9203692 A MX 9203692A MX 9203692 A MX9203692 A MX 9203692A
- Authority
- MX
- Mexico
- Prior art keywords
- quinazoline derivatives
- new
- trifluoromethyl
- nitro
- alkyl
- Prior art date
Links
Abstract
La presente invención se refiere a composiciones farmacéuticas que comprenden derivados de quinazolina nuevos o conocidos de la fórmula I: (fórmula); en donde por ejemplo, R1 es hidrógeno, trifluorometilo o nitro, n es 1 y R2 halógeno, trifluorometilo, nitro, ciano, (1-4C) alquilo, (1-4C)alcoxi, N-(1-4C)alquilamino,N,N-di-((1-4C)alquil)amino, (1-4C)alquiltio, (1-4C)alquilsulfinilo o (1-4C) alquilsulfonilo; y diluyentes farmacéuticamente aceptables o portadores de los mismos; los nuevos derivados de quinazolina y a un procedimiento para su preparación; y el uso de las propiedades inhibitorias del receptor quinasa tirosina tanto de los derivados de quinazolina conocidos como de los nuevos en el tratamiento del cáncer.The present invention relates to pharmaceutical compositions comprising new or known quinazoline derivatives of formula I: (formula); where for example, R1 is hydrogen, trifluoromethyl or nitro, n is 1 and R2 is halogen, trifluoromethyl, nitro, cyano, (1-4C) alkyl, (1-4C) alkoxy, N- (1-4C) alkylamino, N , N-di - ((1-4C) alkyl) amino, (1-4C) alkylthio, (1-4C) alkylsulfinyl or (1-4C) alkylsulfonyl; and pharmaceutically acceptable diluents or carriers thereof; the new quinazoline derivatives and a process for their preparation; and the use of the inhibitory properties of the tyrosine receptor kinase of both known and new quinazoline derivatives in the treatment of cancer.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB919113970A GB9113970D0 (en) | 1991-06-28 | 1991-06-28 | Therapeutic preparations |
GB929201133A GB9201133D0 (en) | 1992-01-20 | 1992-01-20 | Therapeutic preparations |
GB929213181A GB9213181D0 (en) | 1991-06-28 | 1992-06-22 | Therapeutic agents |
Publications (1)
Publication Number | Publication Date |
---|---|
MX9203692A true MX9203692A (en) | 1994-07-29 |
Family
ID=27265736
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX9203692A MX9203692A (en) | 1991-06-28 | 1992-06-29 | THERAPEUTIC PREPARATIONS. |
Country Status (1)
Country | Link |
---|---|
MX (1) | MX9203692A (en) |
-
1992
- 1992-06-29 MX MX9203692A patent/MX9203692A/en not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant or registration | ||
MM | Annulment or lapse due to non-payment of fees |