MX9100603A - Analogos de aica ribosido,sustituidos con imidazol - Google Patents

Analogos de aica ribosido,sustituidos con imidazol

Info

Publication number
MX9100603A
MX9100603A MX9100603A MX9100603A MX9100603A MX 9100603 A MX9100603 A MX 9100603A MX 9100603 A MX9100603 A MX 9100603A MX 9100603 A MX9100603 A MX 9100603A MX 9100603 A MX9100603 A MX 9100603A
Authority
MX
Mexico
Prior art keywords
ribosido
aica
analogs
imidazole
replaced
Prior art date
Application number
MX9100603A
Other languages
English (en)
Inventor
Ernest K Metzner
Harry E Gruber
David A Bullough
Kevin M Mullane
Bheemarao G Ugarkar
Clinton E Browne
Original Assignee
Gensia Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gensia Pharma filed Critical Gensia Pharma
Publication of MX9100603A publication Critical patent/MX9100603A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/052—Imidazole radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
MX9100603A 1990-08-10 1991-08-09 Analogos de aica ribosido,sustituidos con imidazol MX9100603A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US56619790A 1990-08-10 1990-08-10
US73218191A 1991-07-17 1991-07-17

Publications (1)

Publication Number Publication Date
MX9100603A true MX9100603A (es) 1992-04-01

Family

ID=27074103

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9100603A MX9100603A (es) 1990-08-10 1991-08-09 Analogos de aica ribosido,sustituidos con imidazol

Country Status (9)

Country Link
EP (1) EP0542867A4 (es)
JP (1) JPH06500101A (es)
AU (1) AU651131B2 (es)
CA (1) CA2089145A1 (es)
FI (1) FI930553A (es)
IE (1) IE912834A1 (es)
IL (1) IL99125A0 (es)
MX (1) MX9100603A (es)
WO (1) WO1992002213A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL103294A0 (en) * 1991-09-30 1993-05-13 Gensia Pharma Pharmaceutical compositions for preventing tissue damage associated with decreased blood flow
JP2005524662A (ja) * 2002-02-28 2005-08-18 ビオタ インコーポレーティッド ヌクレオシド５’−一リン酸模倣物およびこれらのプロドラッグ
EP2594273A1 (en) 2005-03-28 2013-05-22 Pericor Therapeutics, Inc. Methods, compositions, and formulations for preventing or reducing adverse effects in a patient
WO2009036414A1 (en) 2007-09-13 2009-03-19 University Of South Florida Method of selectively inhibiting pkciota
WO2010040110A1 (en) 2008-10-03 2010-04-08 Pericor Therapeutics, Inc. Methods and compositions for treatment of acute heart failure
US9073960B2 (en) 2011-12-22 2015-07-07 Alios Biopharma, Inc. Substituted nucleosides, nucleotides and analogs thereof
US9441007B2 (en) 2012-03-21 2016-09-13 Alios Biopharma, Inc. Substituted nucleosides, nucleotides and analogs thereof
USRE48171E1 (en) 2012-03-21 2020-08-25 Janssen Biopharma, Inc. Substituted nucleosides, nucleotides and analogs thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT350735B (de) * 1976-08-06 1979-06-11 Hoffmann La Roche Verfahren zur herstellung von neuen ribo- furanosyl-imidazolderivaten
US4575498A (en) * 1983-07-21 1986-03-11 Duke University Method for restoring depleted purine nucleotide pools
US4912092A (en) * 1986-03-27 1990-03-27 The Regents Of The University Of California Methods for increasing extracellular adenosine and for stabilizing mast cells
US5132291A (en) * 1989-01-24 1992-07-21 Gensia Pharmaceuticals, Inc. Antivirals and methods for increasing the antiviral activity of azt

Also Published As

Publication number Publication date
AU651131B2 (en) 1994-07-14
JPH06500101A (ja) 1994-01-06
IL99125A0 (en) 1992-07-15
CA2089145A1 (en) 1992-02-11
EP0542867A1 (en) 1993-05-26
IE912834A1 (en) 1992-02-12
FI930553A0 (fi) 1993-02-09
FI930553A (fi) 1993-03-24
EP0542867A4 (en) 1993-07-28
WO1992002213A1 (en) 1992-02-20
AU8406291A (en) 1992-03-02

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