MX384158B - Método y aparato. - Google Patents

Método y aparato.

Info

Publication number
MX384158B
MX384158B MX2017004730A MX2017004730A MX384158B MX 384158 B MX384158 B MX 384158B MX 2017004730 A MX2017004730 A MX 2017004730A MX 2017004730 A MX2017004730 A MX 2017004730A MX 384158 B MX384158 B MX 384158B
Authority
MX
Mexico
Prior art keywords
ion
ions
modifier
selector
operate
Prior art date
Application number
MX2017004730A
Other languages
English (en)
Other versions
MX2017004730A (es
Inventor
Alastair Clark
Jonathan Atkinson
Original Assignee
Smiths Detection Watford Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smiths Detection Watford Ltd filed Critical Smiths Detection Watford Ltd
Publication of MX2017004730A publication Critical patent/MX2017004730A/es
Publication of MX384158B publication Critical patent/MX384158B/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/62—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
    • G01N27/622—Ion mobility spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/62—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
    • G01N27/622—Ion mobility spectrometry
    • G01N27/623—Ion mobility spectrometry combined with mass spectrometry
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/0027—Methods for using particle spectrometers
    • H01J49/0031—Step by step routines describing the use of the apparatus
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
    • H01J49/0045—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn characterised by the fragmentation or other specific reaction
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
    • H01J49/0045—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn characterised by the fragmentation or other specific reaction
    • H01J49/005—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn characterised by the fragmentation or other specific reaction by collision with gas, e.g. by introducing gas or by accelerating ions with an electric field
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/40—Time-of-flight spectrometers
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/42—Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
    • H01J49/4205—Device types
    • H01J49/421—Mass filters, i.e. deviating unwanted ions without trapping

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Electrochemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)

Abstract

Un filtro de iones para un espectrómetro de masas, el aparato comprende un modificador de iones; un selector de iones configurado para seleccionar un subconjunto de una muestra de iones con base en su movilidad en un gas; y un controlador configurado para operar el modificador de iones en un primer modo para modificar los iones seleccionados por el selector de iones para proporcionar iones producto, y configurado para operar el modificador de iones en un segundo modo para emitir los iones seleccionados por el selector de iones, en donde el filtro de iones está adaptado para proporcionar iones de salida del modificador de iones a una entrada de un espectrómetro de masas.
MX2017004730A 2014-10-14 2015-10-14 Método y aparato. MX384158B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB1418199.4A GB2531292B (en) 2014-10-14 2014-10-14 Method and apparatus
PCT/GB2015/053032 WO2016059406A1 (en) 2014-10-14 2015-10-14 Method and apparatus

Publications (2)

Publication Number Publication Date
MX2017004730A MX2017004730A (es) 2017-11-30
MX384158B true MX384158B (es) 2025-03-14

Family

ID=52001419

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017004730A MX384158B (es) 2014-10-14 2015-10-14 Método y aparato.

Country Status (11)

Country Link
US (2) US10557823B2 (es)
EP (1) EP3207557B1 (es)
JP (1) JP6639491B2 (es)
KR (1) KR102551534B1 (es)
CN (1) CN107078018B (es)
CA (1) CA2964156A1 (es)
GB (1) GB2531292B (es)
MX (1) MX384158B (es)
PL (1) PL3207557T3 (es)
RU (1) RU2713744C2 (es)
WO (1) WO2016059406A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201315145D0 (en) 2013-08-23 2013-10-09 Smiths Detection Watford Ltd Ion Modification
GB2531292B (en) * 2014-10-14 2019-06-12 Smiths Detection Watford Ltd Method and apparatus
GB2566713A (en) * 2017-09-22 2019-03-27 Owlstone Med Ltd Spectrometry system
WO2019236143A1 (en) * 2018-06-04 2019-12-12 The Trustees Of Indiana University Apparatus and method for calibrating or resetting a charge detector
EP3578966B1 (en) * 2018-06-04 2025-11-05 Bruker Scientific LLC Separation of ions according to ion mobility with enhanced resolving power for mass spectrometric analysis
GB2576003B (en) * 2018-07-31 2021-02-03 Smiths Detection Watford Ltd Ion gate configured to fragment ions in ion mobility spectrometry
CN109524290B (zh) * 2018-12-29 2025-04-18 同方威视技术股份有限公司 基于脉冲采样的离子迁移谱仪装置

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US6498342B1 (en) * 1997-06-02 2002-12-24 Advanced Research & Technology Institute Ion separation instrument
US6960761B2 (en) * 1997-06-02 2005-11-01 Advanced Research & Technology Institute Instrument for separating ions in time as functions of preselected ion mobility and ion mass
US6348688B1 (en) * 1998-02-06 2002-02-19 Perseptive Biosystems Tandem time-of-flight mass spectrometer with delayed extraction and method for use
US6822224B2 (en) * 2000-03-14 2004-11-23 National Research Council Canada Tandem high field asymmetric waveform ion mobility spectrometry (FAIMS)tandem mass spectrometry
US6744043B2 (en) * 2000-12-08 2004-06-01 Mds Inc. Ion mobilty spectrometer incorporating an ion guide in combination with an MS device
GB0408751D0 (en) * 2004-04-20 2004-05-26 Micromass Ltd Mass spectrometer
JP4513488B2 (ja) * 2004-10-06 2010-07-28 株式会社日立製作所 イオンモビリティー分析装置及びイオンモビリティー分析方法
US9012840B2 (en) * 2004-12-07 2015-04-21 Micromass Uk Limited Mass spectrometer
GB0522933D0 (en) * 2005-11-10 2005-12-21 Micromass Ltd Mass spectrometer
CA2628922C (en) * 2005-11-10 2016-01-26 Micromass Uk Limited Mass spectrometer
US20070114382A1 (en) * 2005-11-23 2007-05-24 Clemmer David E Ion mobility spectrometer
US8884221B2 (en) * 2006-01-05 2014-11-11 Excellims Corporation High performance ion mobility spectrometer apparatus and methods
PL1971855T3 (pl) * 2006-01-10 2018-10-31 Smiths Detection-Watford Limited Urządzenie i sposób selekcji jonów
US20090283674A1 (en) * 2006-11-07 2009-11-19 Reinhold Pesch Efficient Atmospheric Pressure Interface for Mass Spectrometers and Method
GB0622780D0 (en) * 2006-11-15 2006-12-27 Micromass Ltd Mass spectrometer
GB0704137D0 (en) * 2007-03-03 2007-04-11 Smiths Detection Watford Ltd Ion mobility spectrometers
GB0704547D0 (en) * 2007-03-09 2007-04-18 Smiths Detection Watford Ltd Ion mobility spectrometers
JP4862738B2 (ja) * 2007-05-08 2012-01-25 株式会社日立製作所 イオン移動度分析装置およびイオン移動度分離／質量分析複合装置
GB2457769B (en) 2007-09-14 2010-07-14 Micromass Ltd Method of ion mobility separation
US8872102B2 (en) * 2008-01-17 2014-10-28 Indian University Research and Technology Corporation Ion mobility spectrometer and method of operating same
WO2010124019A1 (en) * 2009-04-21 2010-10-28 Excellims Corporation Intelligently controlled spectrometer methods and apparatus
GB0907619D0 (en) * 2009-05-01 2009-06-10 Shimadzu Res Lab Europe Ltd Ion analysis apparatus and method of use
GB201101132D0 (en) 2011-01-21 2011-03-09 Smiths Detection Watford Ltd Combination ion gate and modifier
US8536518B2 (en) * 2011-06-27 2013-09-17 U.S. Department of Homeland Security Ion mobility spectrometer to mass spectrometer interface
KR101936838B1 (ko) * 2011-12-05 2019-01-09 스미스 디텍션 몬트리올 인코포레이티드 질량 분광 분석법을 사용하여 샘플 분석하는 시스템, 장치 및 방법
PL3617697T3 (pl) 2012-02-16 2022-08-16 Smiths Detection-Watford Limited Zsynchronizowana modyfikacja jonów
GB201205009D0 (en) * 2012-03-22 2012-05-09 Micromass Ltd Multi-dimensional survey scans for improved data dependent acquisitions (DDA)
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GB2531292B (en) * 2014-10-14 2019-06-12 Smiths Detection Watford Ltd Method and apparatus

Also Published As

Publication number Publication date
KR20170066464A (ko) 2017-06-14
JP6639491B2 (ja) 2020-02-05
EP3207557B1 (en) 2024-05-22
CN107078018B (zh) 2020-06-02
MX2017004730A (es) 2017-11-30
US10557823B2 (en) 2020-02-11
WO2016059406A1 (en) 2016-04-21
RU2017114148A (ru) 2018-11-15
RU2713744C2 (ru) 2020-02-07
RU2017114148A3 (es) 2019-04-10
KR102551534B1 (ko) 2023-07-04
EP3207557A1 (en) 2017-08-23
US20200173961A1 (en) 2020-06-04
CA2964156A1 (en) 2016-04-21
US20170241951A1 (en) 2017-08-24
GB201418199D0 (en) 2014-11-26
PL3207557T3 (pl) 2024-07-22
GB2531292A (en) 2016-04-20
EP3207557C0 (en) 2024-05-22
US11215582B2 (en) 2022-01-04
CN107078018A (zh) 2017-08-18
GB2531292B (en) 2019-06-12
JP2017536536A (ja) 2017-12-07

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