MX358118B - Vacuna contra el virus de la leucemia bovina. - Google Patents

Vacuna contra el virus de la leucemia bovina.

Info

Publication number
MX358118B
MX358118B MX2015011064A MX2015011064A MX358118B MX 358118 B MX358118 B MX 358118B MX 2015011064 A MX2015011064 A MX 2015011064A MX 2015011064 A MX2015011064 A MX 2015011064A MX 358118 B MX358118 B MX 358118B
Authority
MX
Mexico
Prior art keywords
nucleic acids
vectors
blv
recombinant
viruses
Prior art date
Application number
MX2015011064A
Other languages
English (en)
Other versions
MX2015011064A (es
Inventor
Willems Luc
Trono Karina
Original Assignee
Univ Liege
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Liege filed Critical Univ Liege
Publication of MX2015011064A publication Critical patent/MX2015011064A/es
Publication of MX358118B publication Critical patent/MX358118B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/21—Retroviridae, e.g. equine infectious anemia virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/14011—Deltaretrovirus, e.g. bovine leukeamia virus
    • C12N2740/14021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/14011—Deltaretrovirus, e.g. bovine leukeamia virus
    • C12N2740/14022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/14011—Deltaretrovirus, e.g. bovine leukeamia virus
    • C12N2740/14034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/14011—Deltaretrovirus, e.g. bovine leukeamia virus
    • C12N2740/14041—Use of virus, viral particle or viral elements as a vector
    • C12N2740/14043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/14011—Deltaretrovirus, e.g. bovine leukeamia virus
    • C12N2740/14061—Methods of inactivation or attenuation
    • C12N2740/14062—Methods of inactivation or attenuation by genetic engineering
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/14011—Deltaretrovirus, e.g. bovine leukeamia virus
    • C12N2740/14071—Demonstrated in vivo effect

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La presente invención se refiere a virus recombinantes de la leucemia bovina que tienen un fenotipo atenuado y comprenden una combinación de al menos dos mutaciones específicas. La invención también proporciona ácidos nucleicos recombinantes que codifican dichos virus, vectores que comprenden dichos ácidos nucleicos, y células hospedadoras que comprenden dichos ácidos nucleicos o vectores. Los virus BLV recombinantes atenuados, ácidos nucleicos recombinantes, vectores y células hospedadoras permiten la preparación de vacunas mejoradas, en particular vacunas adecuadas para el tratamiento profiláctico de enfermedades asociadas a BLV en sujetos. La invención proporciona además métodos para tratar enfermedades asociadas a BLV en sujetos y composiciones farmacéuticas adecuadas para el uso en estos métodos.
MX2015011064A 2013-02-27 2014-02-27 Vacuna contra el virus de la leucemia bovina. MX358118B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361769971P 2013-02-27 2013-02-27
EP13156921 2013-02-27
PCT/EP2014/053855 WO2014131844A1 (en) 2013-02-27 2014-02-27 Vaccine against bovine leukemia virus

Publications (2)

Publication Number Publication Date
MX2015011064A MX2015011064A (es) 2016-03-01
MX358118B true MX358118B (es) 2018-08-06

Family

ID=47749713

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015011064A MX358118B (es) 2013-02-27 2014-02-27 Vacuna contra el virus de la leucemia bovina.

Country Status (7)

Country Link
US (2) US10029006B2 (es)
EP (1) EP2961425B1 (es)
AR (1) AR094912A1 (es)
BR (1) BR112015020604B1 (es)
CA (1) CA2901508A1 (es)
MX (1) MX358118B (es)
WO (1) WO2014131844A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022504166A (ja) * 2018-10-09 2022-01-13 ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒル 調節された遺伝子編集システム

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2396978C1 (ru) 2009-03-05 2010-08-20 Федеральное государственное образовательное учреждение высшего профессионального образования Курская государственная сельскохозяйственная академия имени профессора И.И. Иванова Способ профилактики развития лейкоза крупного рогатого скота

Also Published As

Publication number Publication date
EP2961425A1 (en) 2016-01-06
US11154611B2 (en) 2021-10-26
MX2015011064A (es) 2016-03-01
EP2961425B1 (en) 2018-05-30
US20190000963A1 (en) 2019-01-03
BR112015020604A2 (pt) 2017-10-10
US20160045593A1 (en) 2016-02-18
CA2901508A1 (en) 2014-09-04
WO2014131844A1 (en) 2014-09-04
BR112015020604B1 (pt) 2023-11-21
US10029006B2 (en) 2018-07-24
AR094912A1 (es) 2015-09-09

Similar Documents

Publication Publication Date Title
MX2022005291A (es) Vacunas para el tratamiento y prevencion del cancer.
WO2013106834A3 (en) Immunogenic wt-1 peptides and methods of use thereof
IN2015DN02546A (es)
WO2017191258A8 (en) INFLUENZA MRNA VACCINES
MX2021006931A (es) Antigenos del virus de la inmunodeficiencia humana, vectores, composiciones y metodos de uso de estos.
MX2016016722A (es) Coronavirus.
WO2014113490A3 (en) Immunogenic wt-1 peptides and methods of use thereof
PT2643345T (pt) Péptidos imunogénicos para utilizar na prevenção e/ou no tratamento de doenças infecciosas, doenças autoimunes, respostas imunitárias a alofatores, doenças alérgicas, tumores, rejeição de enxertos e respostas imunitárias contra vetores virais usados para a terapêutica de genes ou na vacinação genética
HK1225631A1 (zh) 免疫原性中东呼吸综合征冠状病毒(mers-cov)组合物和方法
MX2025008006A (es) Vacunas novedosas del vph16, composiciones y metodos de uso de las mismas
WO2016046234A3 (en) Recombinant phe-free proteins for use in the treatment of phenylketonuria
MX2018004598A (es) Cepas vacunales recombinantes de listeria y métodos para usar las mismas en la inmunoterapia contra el cáncer.
NZ703597A (en) Mutant fragments of ospa and methods and uses relating thereto
MX2021013109A (es) Proceso de preparacion de una vacuna tetravalente atenuada contra el virus del dengue.
NZ721015A (en) Mutant fragments of ospa and methods and uses relating thereto
PH12018000197A1 (en) Hand, foot, and mouth vaccines and methods of manufacture and use thereof
MD20120127A2 (en) Recombinant Koi herpesvirus (KHV), method for its production and vaccine for the prevention of a disease caused by KHV
ZA202003070B (en) Lassa vaccine
PH12017501100B1 (en) Recombinant swinepox virus and vaccines
MX2013003245A (es) Vacuna contra virus de diarrea viral de bovinos.
PH12017500419B1 (en) Recoded arbovirus and vaccines
WO2016011432A3 (en) Identification of immunogenic mhc class ii peptides for immune-based therapy
MX358118B (es) Vacuna contra el virus de la leucemia bovina.
MX2017014343A (es) Compuestos peptidomimeticos que neutralizan el virus influenza.
MX2018013358A (es) Vacunas para el virus del papiloma humano y metodos para su uso.

Legal Events

Date Code Title Description
FG Grant or registration