MX2025008101A - Compuestos moduladores de receptores de dopamina d3/d2 - Google Patents
Compuestos moduladores de receptores de dopamina d3/d2Info
- Publication number
- MX2025008101A MX2025008101A MX2025008101A MX2025008101A MX2025008101A MX 2025008101 A MX2025008101 A MX 2025008101A MX 2025008101 A MX2025008101 A MX 2025008101A MX 2025008101 A MX2025008101 A MX 2025008101A MX 2025008101 A MX2025008101 A MX 2025008101A
- Authority
- MX
- Mexico
- Prior art keywords
- dopamine
- modulating compounds
- receptor modulating
- compounds
- sup
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Psychiatry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202363479530P | 2023-01-11 | 2023-01-11 | |
| PCT/IB2024/000026 WO2024150068A2 (en) | 2023-01-11 | 2024-01-10 | Dopamine d3/d2 receptor modulating compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2025008101A true MX2025008101A (es) | 2025-08-01 |
Family
ID=89573273
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2025008101A MX2025008101A (es) | 2023-01-11 | 2025-07-10 | Compuestos moduladores de receptores de dopamina d3/d2 |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US12168007B1 (enExample) |
| EP (1) | EP4400495A1 (enExample) |
| JP (2) | JP7686096B2 (enExample) |
| KR (2) | KR102921799B1 (enExample) |
| CN (2) | CN122427144A (enExample) |
| AR (1) | AR131577A1 (enExample) |
| AU (1) | AU2024208533A1 (enExample) |
| CL (2) | CL2025002035A1 (enExample) |
| CO (1) | CO2025010725A2 (enExample) |
| GE (1) | GEAP202516807A (enExample) |
| IL (1) | IL321654A (enExample) |
| JO (1) | JOP20250164A1 (enExample) |
| MX (1) | MX2025008101A (enExample) |
| PE (1) | PE20260287A1 (enExample) |
| TW (1) | TW202432139A (enExample) |
| WO (1) | WO2024150068A2 (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2026153547A1 (zh) * | 2025-01-20 | 2026-07-23 | 上海则正医药科技股份有限公司 | D3/d2受体部分激动剂及制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU227534B1 (en) | 2003-08-04 | 2011-08-29 | Richter Gedeon Nyrt | (thio)carbamoyl-cyclohexane derivatives, process for producing them and pharmaceutical compositions containing them |
| EP1870405A1 (en) | 2006-06-22 | 2007-12-26 | Bioprojet | Carbonylated (Aza)cyclohexanes as dopamine D3 receptor ligands |
| HUP0800765A2 (en) | 2008-12-18 | 2010-11-29 | Richter Gedeon Nyrt | A new process for the preparation of piperazine derivatives and their hydrochloric salts |
| JP5732453B2 (ja) | 2009-06-25 | 2015-06-10 | アルカーメス ファーマ アイルランド リミテッド | Ｎｈ酸性化合物のプロドラッグ |
| WO2020156312A1 (zh) | 2019-01-30 | 2020-08-06 | 江苏豪森药业集团有限公司 | 一种多环类衍生物调节剂、其制备方法和应用 |
| US12617759B2 (en) | 2019-10-29 | 2026-05-05 | Shanghai Hansoh Biomedical Co., Ltd. | Modifier of four-membered ring derivative, preparation method and application thereof |
| KR102947882B1 (ko) | 2019-11-05 | 2026-04-03 | 상하이 한서 바이오메디컬 컴퍼니 리미티드 | 벤조티오펜 유도체 조절제, 그의 제조 방법 및 그의 용도 |
-
2024
- 2024-01-08 KR KR1020240002897A patent/KR102921799B1/ko active Active
- 2024-01-09 AR ARP240100045A patent/AR131577A1/es unknown
- 2024-01-10 US US18/409,478 patent/US12168007B1/en active Active
- 2024-01-10 IL IL321654A patent/IL321654A/en unknown
- 2024-01-10 AU AU2024208533A patent/AU2024208533A1/en active Pending
- 2024-01-10 GE GEAP202516807A patent/GEAP202516807A/en unknown
- 2024-01-10 TW TW113101017A patent/TW202432139A/zh unknown
- 2024-01-10 WO PCT/IB2024/000026 patent/WO2024150068A2/en not_active Ceased
- 2024-01-10 CN CN202610307661.1A patent/CN122427144A/zh active Pending
- 2024-01-10 PE PE2025001450A patent/PE20260287A1/es unknown
- 2024-01-10 EP EP24151077.5A patent/EP4400495A1/en active Pending
- 2024-01-10 JP JP2024001696A patent/JP7686096B2/ja active Active
- 2024-01-10 CN CN202480007498.6A patent/CN120569367A/zh active Pending
- 2024-10-29 US US18/930,023 patent/US20250049786A1/en active Pending
-
2025
- 2025-05-19 JP JP2025083110A patent/JP2025122072A/ja active Pending
- 2025-07-09 CL CL2025002035A patent/CL2025002035A1/es unknown
- 2025-07-10 MX MX2025008101A patent/MX2025008101A/es unknown
- 2025-07-10 JO JOJO/P/2025/0164A patent/JOP20250164A1/ar unknown
- 2025-08-05 CO CONC2025/0010725A patent/CO2025010725A2/es unknown
-
2026
- 2026-01-29 KR KR1020260017571A patent/KR20260019592A/ko active Pending
- 2026-02-25 CL CL2026000558A patent/CL2026000558A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CL2025002035A1 (es) | 2025-10-03 |
| CN120569367A (zh) | 2025-08-29 |
| EP4400495A1 (en) | 2024-07-17 |
| CO2025010725A2 (es) | 2025-08-29 |
| KR102921799B1 (ko) | 2026-02-04 |
| JP2024098972A (ja) | 2024-07-24 |
| PE20260287A1 (es) | 2026-02-10 |
| US12168007B1 (en) | 2024-12-17 |
| TW202432139A (zh) | 2024-08-16 |
| US20250049786A1 (en) | 2025-02-13 |
| KR20260019592A (ko) | 2026-02-10 |
| WO2024150068A3 (en) | 2024-08-22 |
| GEAP202516807A (en) | 2025-08-25 |
| AU2024208533A1 (en) | 2025-07-10 |
| AR131577A1 (es) | 2025-04-09 |
| JP7686096B2 (ja) | 2025-05-30 |
| JP2025122072A (ja) | 2025-08-20 |
| CL2026000558A1 (es) | 2026-06-05 |
| JOP20250164A1 (ar) | 2025-07-10 |
| IL321654A (en) | 2025-08-01 |
| KR20240112213A (ko) | 2024-07-18 |
| WO2024150068A2 (en) | 2024-07-18 |
| CN122427144A (zh) | 2026-07-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PH12021551256A1 (en) | Pantetheine derivatives and uses thereof | |
| EP4699609A3 (en) | Heterocyclic glp-1 agonists | |
| MX2022013482A (es) | Compuestos utiles para inhibir la quinasa ret. | |
| MX2022008066A (es) | Compuestos triciclicos sustituidos. | |
| PH12022552056A1 (en) | Heterocyclic glp-1 agonists | |
| MX2022015703A (es) | Compuestos para el tratamiento de enfermedades y trastornos asociados a braf. | |
| MX2022004450A (es) | Aminas de heteroaril-bifenilo para el tratamiento de enfermedades pd-l1. | |
| MX2021000887A (es) | Compuestos espiroheterociclicos y metodos de uso de los mismos para el tratamiento de cancer. | |
| MX2025008327A (es) | Composiciones y metodos para el tratamiento de trastornos del snc | |
| MX2022004451A (es) | Heteroaril-bifenil-amidas para el tratamiento de enfermedades relacionadas con el ligando pd-l1. | |
| IL176107A0 (en) | Azabicyclic heterocycles as cannabinoid receptor modulators | |
| PA8580301A1 (es) | Nuevos derivados de benzoimidazol utiles como agentes antiproliferativos | |
| MX2021011811A (es) | Protacs que degradan el receptor de estrogeno. | |
| SE9903998D0 (sv) | New compounds | |
| EP2368887B8 (en) | 1, 2, 3-triazole derivatives for use as stearoyl-coa desaturase inhibitors | |
| MA34604B1 (fr) | Derives de la pyrazine en tant que bloqueurs de l'enac | |
| DE602004011394D1 (en) | Thiazolderivate | |
| MX2022009243A (es) | Moduladores de la via de respuesta integrada al estres. | |
| MX2024009177A (es) | Compuestos y metodos de uso | |
| MX2023015139A (es) | Inhibidores de mutacion de her2. | |
| SE9903997D0 (sv) | New compounds | |
| ZA202200660B (en) | Process for the preparation of ridinilazole and crystalline forms thereof | |
| MX2025010256A (es) | Derivados de hidroquinazolina para el tratamiento de una enfermedad o un trastorno | |
| MX2023009954A (es) | Compuestos de aminopirimidina y métodos de uso de estos. | |
| MX2023009285A (es) | Compuestos novedosos. |