MX2025008101A - Compuestos moduladores de receptores de dopamina d3/d2 - Google Patents

Compuestos moduladores de receptores de dopamina d3/d2

Info

Publication number
MX2025008101A
MX2025008101A MX2025008101A MX2025008101A MX2025008101A MX 2025008101 A MX2025008101 A MX 2025008101A MX 2025008101 A MX2025008101 A MX 2025008101A MX 2025008101 A MX2025008101 A MX 2025008101A MX 2025008101 A MX2025008101 A MX 2025008101A
Authority
MX
Mexico
Prior art keywords
dopamine
modulating compounds
receptor modulating
compounds
sup
Prior art date
Application number
MX2025008101A
Other languages
English (en)
Spanish (es)
Inventor
István Borza
Éles János
Bálint Menczinger
Déak Szilvia Bodnárné
Original Assignee
Richter Gedeon Nyrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Nyrt filed Critical Richter Gedeon Nyrt
Publication of MX2025008101A publication Critical patent/MX2025008101A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/135Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/155Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
MX2025008101A 2023-01-11 2025-07-10 Compuestos moduladores de receptores de dopamina d3/d2 MX2025008101A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202363479530P 2023-01-11 2023-01-11
PCT/IB2024/000026 WO2024150068A2 (en) 2023-01-11 2024-01-10 Dopamine d3/d2 receptor modulating compounds

Publications (1)

Publication Number Publication Date
MX2025008101A true MX2025008101A (es) 2025-08-01

Family

ID=89573273

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2025008101A MX2025008101A (es) 2023-01-11 2025-07-10 Compuestos moduladores de receptores de dopamina d3/d2

Country Status (13)

Country Link
US (2) US12168007B1 (enExample)
EP (1) EP4400495A1 (enExample)
JP (2) JP7686096B2 (enExample)
CN (1) CN120569367A (enExample)
AR (1) AR131577A1 (enExample)
AU (1) AU2024208533A1 (enExample)
CL (1) CL2025002035A1 (enExample)
CO (1) CO2025010725A2 (enExample)
GE (1) GEAP202516807A (enExample)
IL (1) IL321654A (enExample)
MX (1) MX2025008101A (enExample)
TW (1) TW202432139A (enExample)
WO (1) WO2024150068A2 (enExample)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU227534B1 (en) 2003-08-04 2011-08-29 Richter Gedeon Nyrt (thio)carbamoyl-cyclohexane derivatives, process for producing them and pharmaceutical compositions containing them
EP1870405A1 (en) 2006-06-22 2007-12-26 Bioprojet Carbonylated (Aza)cyclohexanes as dopamine D3 receptor ligands
HUP0800765A2 (en) 2008-12-18 2010-11-29 Richter Gedeon Nyrt A new process for the preparation of piperazine derivatives and their hydrochloric salts
US8686009B2 (en) 2009-06-25 2014-04-01 Alkermes Pharma Ireland Limited Prodrugs of NH-acidic compounds
WO2020156312A1 (zh) 2019-01-30 2020-08-06 江苏豪森药业集团有限公司 一种多环类衍生物调节剂、其制备方法和应用
CN118772126A (zh) 2019-10-29 2024-10-15 上海翰森生物医药科技有限公司 四元环类衍生物调节剂、其制备方法和应用
WO2021088920A1 (zh) 2019-11-05 2021-05-14 上海翰森生物医药科技有限公司 苯并噻吩类衍生物调节剂、其制备方法和应用

Also Published As

Publication number Publication date
JP7686096B2 (ja) 2025-05-30
KR20240112213A (ko) 2024-07-18
TW202432139A (zh) 2024-08-16
CN120569367A (zh) 2025-08-29
JP2024098972A (ja) 2024-07-24
JP2025122072A (ja) 2025-08-20
US12168007B1 (en) 2024-12-17
GEAP202516807A (en) 2025-08-25
US20250049786A1 (en) 2025-02-13
WO2024150068A3 (en) 2024-08-22
CL2025002035A1 (es) 2025-10-03
WO2024150068A2 (en) 2024-07-18
IL321654A (en) 2025-08-01
AU2024208533A1 (en) 2025-07-10
CO2025010725A2 (es) 2025-08-29
AR131577A1 (es) 2025-04-09
EP4400495A1 (en) 2024-07-17

Similar Documents

Publication Publication Date Title
CR20230310A (es) Inhibidores de prmt5
MX2023009222A (es) Inhibidores tricíclicos-amido-bicíclicos de prmt5.
PH12022552056A1 (en) Heterocyclic glp-1 agonists
PH12021551256A1 (en) Pantetheine derivatives and uses thereof
MX2022015703A (es) Compuestos para el tratamiento de enfermedades y trastornos asociados a braf.
MX2022013482A (es) Compuestos utiles para inhibir la quinasa ret.
WO2021147236A9 (zh) 取代氨基丙酸酯类化合物在治疗SARS-CoV-2感染中的应用
MX2021000887A (es) Compuestos espiroheterociclicos y metodos de uso de los mismos para el tratamiento de cancer.
MX2025008327A (es) Composiciones y metodos para el tratamiento de trastornos del snc
MX2022004451A (es) Heteroaril-bifenil-amidas para el tratamiento de enfermedades relacionadas con el ligando pd-l1.
NZ793536A (en) Imidazolidinone derivatives and medical use thereof
IL176107A0 (en) Azabicyclic heterocycles as cannabinoid receptor modulators
PA8580301A1 (es) Nuevos derivados de benzoimidazol utiles como agentes antiproliferativos
EP2368887B8 (en) 1, 2, 3-triazole derivatives for use as stearoyl-coa desaturase inhibitors
MA34604B1 (fr) Derives de la pyrazine en tant que bloqueurs de l'enac
DE602004011394D1 (en) Thiazolderivate
MX2022009243A (es) Moduladores de la via de respuesta integrada al estres.
SE9903997D0 (sv) New compounds
MX2023015139A (es) Inhibidores de mutacion de her2.
ZA202200660B (en) Process for the preparation of ridinilazole and crystalline forms thereof
GEAP202516737A (en) Compounds for treating cancer
MX2023009954A (es) Compuestos de aminopirimidina y métodos de uso de estos.
MX2021003508A (es) Derivados de 5-azaindazol como antagonistas del receptor de adenosina.
MX2023006176A (es) Nuevos derivados de indazol acetileno.
MX2025008101A (es) Compuestos moduladores de receptores de dopamina d3/d2