MX2023008829A - Metodos para preparar bisfosfocinas. - Google Patents

Metodos para preparar bisfosfocinas.

Info

Publication number
MX2023008829A
MX2023008829A MX2023008829A MX2023008829A MX2023008829A MX 2023008829 A MX2023008829 A MX 2023008829A MX 2023008829 A MX2023008829 A MX 2023008829A MX 2023008829 A MX2023008829 A MX 2023008829A MX 2023008829 A MX2023008829 A MX 2023008829A
Authority
MX
Mexico
Prior art keywords
bisphosphocins
methods
preparing
dialcoholic
tetrazole
Prior art date
Application number
MX2023008829A
Other languages
English (en)
Inventor
Kelvin Cooper
Original Assignee
Lakewood Amedex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lakewood Amedex Inc filed Critical Lakewood Amedex Inc
Publication of MX2023008829A publication Critical patent/MX2023008829A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C07H1/02—Phosphorylation
    • C07H1/04—Introducing polyphosphoric acid radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/091—Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Los métodos para sintetizar bisfosfocinas usan la modificación química de compuestos dialcohólicos que evita el uso de tetrazol e hidroperóxido de butilo terciario.
MX2023008829A 2021-07-22 2022-07-22 Metodos para preparar bisfosfocinas. MX2023008829A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163224594P 2021-07-22 2021-07-22
US202263300354P 2022-01-18 2022-01-18
PCT/US2022/038040 WO2023004130A1 (en) 2021-07-22 2022-07-22 Methods for preparing bisphosphocins

Publications (1)

Publication Number Publication Date
MX2023008829A true MX2023008829A (es) 2023-08-10

Family

ID=84980131

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2023008829A MX2023008829A (es) 2021-07-22 2022-07-22 Metodos para preparar bisfosfocinas.

Country Status (7)

Country Link
US (1) US20230092578A1 (es)
EP (1) EP4373494A1 (es)
KR (1) KR20240037174A (es)
CA (1) CA3209796A1 (es)
IL (1) IL304289A (es)
MX (1) MX2023008829A (es)
WO (1) WO2023004130A1 (es)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7868162B2 (en) * 1998-12-30 2011-01-11 Lakewood-Amedex, Inc. Antimicrobial and antiviral compounds and methods for their use
AU2010221419B2 (en) * 2009-03-02 2015-10-01 Alnylam Pharmaceuticals, Inc. Nucleic acid chemical modifications
US11096954B2 (en) * 2017-06-12 2021-08-24 Lakewood Amedex, Inc. Bisphosphocin gel formulations and uses thereof

Also Published As

Publication number Publication date
KR20240037174A (ko) 2024-03-21
EP4373494A1 (en) 2024-05-29
IL304289A (en) 2023-09-01
CA3209796A1 (en) 2023-01-26
WO2023004130A1 (en) 2023-01-26
US20230092578A1 (en) 2023-03-23

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