MX2023008829A - Metodos para preparar bisfosfocinas. - Google Patents

Metodos para preparar bisfosfocinas.

Info

Publication number
MX2023008829A
MX2023008829A MX2023008829A MX2023008829A MX2023008829A MX 2023008829 A MX2023008829 A MX 2023008829A MX 2023008829 A MX2023008829 A MX 2023008829A MX 2023008829 A MX2023008829 A MX 2023008829A MX 2023008829 A MX2023008829 A MX 2023008829A
Authority
MX
Mexico
Prior art keywords
bisphosphocins
methods
preparing
dialcoholic
tetrazole
Prior art date
Application number
MX2023008829A
Other languages
English (en)
Inventor
Kelvin Cooper
Original Assignee
Lakewood Amedex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lakewood Amedex Inc filed Critical Lakewood Amedex Inc
Publication of MX2023008829A publication Critical patent/MX2023008829A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C07H1/02—Phosphorylation
    • C07H1/04—Introducing polyphosphoric acid radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/091—Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C07H1/02—Phosphorylation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Los métodos para sintetizar bisfosfocinas usan la modificación química de compuestos dialcohólicos que evita el uso de tetrazol e hidroperóxido de butilo terciario.
MX2023008829A 2021-07-22 2022-07-22 Metodos para preparar bisfosfocinas. MX2023008829A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163224594P 2021-07-22 2021-07-22
US202263300354P 2022-01-18 2022-01-18
PCT/US2022/038040 WO2023004130A1 (en) 2021-07-22 2022-07-22 Methods for preparing bisphosphocins

Publications (1)

Publication Number Publication Date
MX2023008829A true MX2023008829A (es) 2023-08-10

Family

ID=84980131

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2023008829A MX2023008829A (es) 2021-07-22 2022-07-22 Metodos para preparar bisfosfocinas.

Country Status (8)

Country Link
US (1) US20230092578A1 (es)
EP (1) EP4373494A1 (es)
JP (1) JP2024525259A (es)
KR (1) KR20240037174A (es)
CA (1) CA3209796A1 (es)
IL (1) IL304289A (es)
MX (1) MX2023008829A (es)
WO (1) WO2023004130A1 (es)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7868162B2 (en) * 1998-12-30 2011-01-11 Lakewood-Amedex, Inc. Antimicrobial and antiviral compounds and methods for their use
CN100400542C (zh) * 2006-03-30 2008-07-09 上海大学 一种磷酸脂的合成方法
CA2753975C (en) * 2009-03-02 2017-09-26 Alnylam Pharmaceuticals, Inc. Nucleic acid chemical modifications
CN110612143B (zh) * 2017-03-10 2021-07-02 莱克伍德阿美达克斯股份有限公司 抗微生物化合物、组合物及其用途
CA3066722A1 (en) * 2017-06-12 2018-12-20 Lakewood Amedex, Inc Bisphosphocin gel formulations and uses thereof
JP7533920B2 (ja) * 2019-04-26 2024-08-14 株式会社 レオロジー機能食品研究所 リン酸エステルの新規合成法

Also Published As

Publication number Publication date
EP4373494A1 (en) 2024-05-29
WO2023004130A1 (en) 2023-01-26
US20230092578A1 (en) 2023-03-23
JP2024525259A (ja) 2024-07-12
CA3209796A1 (en) 2023-01-26
IL304289A (en) 2023-09-01
KR20240037174A (ko) 2024-03-21

Similar Documents

Publication Publication Date Title
PH12019501812A1 (en) Compositions and methods for the treatment of hemoglobinopathies
SG11201909186YA (en) Triazole silane compound, method for synthesizing said compound and use thereof
MX2022001829A (es) Proceso de fabricación de moduladores de regulador de conductancia transmembrana de la fibrosis quística (cftr).
PH12020500655A1 (en) Compounds
MX2022007576A (es) Degradadores de cinasas asociadas al receptor de interleucina-1 (irak) y usos de los mismos.
PH12019501690A1 (en) Pyrimidine compound and pharmaceutical use thereof
MX2023007852A (es) Degradadores de cinasas asociadas al receptor de interleucina-1 (irak) y usos de los mismos.
PH12020500105A1 (en) Bicyclic ketone compounds and methods of use thereof
MX2022007841A (es) Degradadores del regulador dependiente de actina asociado a la matriz relacionado con el complejo switch/sacarosa no fermentable de la subfamilia a de la cromatina (smarca)y usos de los mismos.
MX2017013100A (es) Proceso para aislar y purificar ambrox.
TN2019000211A1 (en) Antitumoral compounds
AU2014375162A1 (en) Gypsum plaster-based material containing casein and activated carbon
ZA202101487B (en) Novel compounds
MX2023006719A (es) Degradadores de cinasas asociadas con el receptor de interleucina 1 (irak) y sus usos.
MX2023014154A (es) Anticuerpos anti-ccr8.
MX2021013507A (es) Proceso para la preparacion de inhibidores del canal de cloruro ciec-1.
MX2023008829A (es) Metodos para preparar bisfosfocinas.
TN2020000050A1 (en) Novel phenylpyridine derivative and pharmaceutical composition containing same
WO2019060475A3 (en) SYNTHESIS OF ORGANO-CHLOROSILANES FROM ORGANOSILANES
CR20210614A (es) Nuevos inhibidores de egfr
MX2024005138A (es) Degradadores de cinasa-4 asociada al receptor de la interleucina-1 (irak-4) y sintesis de los mismos.
MX2021012357A (es) Proceso para preparar compuestos de acido carbamoiloximetil triazol ciclohexilico.
MX2021004288A (es) Nuevo proceso para la sintesis de derivados de piperazinil-etoxi-bromofenilo y su aplicacion en la produccion de compuestos que los contienen.
MX2022008398A (es) Metodos para la preparacion de 3-bromo-1-(3-cloropiridin-2-il)-1h- pirazol-5-carboxilato de etilo.
MX2023004950A (es) Proceso para purificacion de pleuromutilinas.