MX2023007175A - Agentes para el diagnostico por imagenes predirigidas. - Google Patents

Agentes para el diagnostico por imagenes predirigidas.

Info

Publication number
MX2023007175A
MX2023007175A MX2023007175A MX2023007175A MX2023007175A MX 2023007175 A MX2023007175 A MX 2023007175A MX 2023007175 A MX2023007175 A MX 2023007175A MX 2023007175 A MX2023007175 A MX 2023007175A MX 2023007175 A MX2023007175 A MX 2023007175A
Authority
MX
Mexico
Prior art keywords
imaging agents
pretargeting imaging
pretargeting
compounds
methods
Prior art date
Application number
MX2023007175A
Other languages
English (en)
Inventor
Hui Xiong
Aldo Cagnolini
Adam Thomas Hoye
Ximin Li
Justin Patrick Wright
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of MX2023007175A publication Critical patent/MX2023007175A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/041Heterocyclic compounds
    • A61K51/044Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/041Heterocyclic compounds
    • A61K51/044Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0455Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0495Pretargeting
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/002Heterocyclic compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01Sulfonic acids
    • C07C309/02Sulfonic acids having sulfo groups bound to acyclic carbon atoms
    • C07C309/03Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C309/06Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing halogen atoms, or nitro or nitroso groups bound to the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

La presente invención proporciona compuestos novedosos: (ver Fórmulas) métodos para fabricar dichos compuestos, métodos para utilizar dichos compuestos para el diagnóstico por imágenes predirigidas y preparaciones de formulaciones para dicho uso.
MX2023007175A 2020-12-16 2021-12-15 Agentes para el diagnostico por imagenes predirigidas. MX2023007175A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063126100P 2020-12-16 2020-12-16
US202163166484P 2021-03-26 2021-03-26
PCT/US2021/063552 WO2022132924A1 (en) 2020-12-16 2021-12-15 Pretargeting imaging agents

Publications (1)

Publication Number Publication Date
MX2023007175A true MX2023007175A (es) 2023-06-30

Family

ID=80112113

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2023007175A MX2023007175A (es) 2020-12-16 2021-12-15 Agentes para el diagnostico por imagenes predirigidas.

Country Status (10)

Country Link
US (1) US20240034722A1 (es)
EP (1) EP4262885A1 (es)
JP (1) JP2023554004A (es)
KR (1) KR20230107651A (es)
AU (1) AU2021400944B2 (es)
CA (1) CA3200750A1 (es)
IL (1) IL303700A (es)
MX (1) MX2023007175A (es)
TW (1) TWI809597B (es)
WO (1) WO2022132924A1 (es)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017059397A1 (en) 2015-10-01 2017-04-06 Whitehead Institute For Biomedical Research Labeling of antibodies
KR20220012326A (ko) 2019-05-24 2022-02-03 듀크 유니버시티 18f-방사선 표지된 생체 분자

Also Published As

Publication number Publication date
AU2021400944B2 (en) 2023-12-21
JP2023554004A (ja) 2023-12-26
IL303700A (en) 2023-08-01
EP4262885A1 (en) 2023-10-25
AU2021400944A1 (en) 2023-06-22
KR20230107651A (ko) 2023-07-17
CA3200750A1 (en) 2022-06-23
TWI809597B (zh) 2023-07-21
US20240034722A1 (en) 2024-02-01
WO2022132924A1 (en) 2022-06-23
TW202237579A (zh) 2022-10-01

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