MX2023006205A - Tratamiento y diagnostico fotodinamico. - Google Patents
Tratamiento y diagnostico fotodinamico.Info
- Publication number
- MX2023006205A MX2023006205A MX2023006205A MX2023006205A MX2023006205A MX 2023006205 A MX2023006205 A MX 2023006205A MX 2023006205 A MX2023006205 A MX 2023006205A MX 2023006205 A MX2023006205 A MX 2023006205A MX 2023006205 A MX2023006205 A MX 2023006205A
- Authority
- MX
- Mexico
- Prior art keywords
- phyllochlorin
- analogues
- pharmaceutically acceptable
- diagnosis
- acceptable salts
- Prior art date
Links
- 238000003745 diagnosis Methods 0.000 title abstract 3
- 238000002428 photodynamic therapy Methods 0.000 title abstract 3
- KWVYZVYHZCFYIY-UHFFFAOYSA-N phyllochlorin Chemical class N1C(C=C2C(C(CCC(=O)OC)C(=N2)C(C)=C2NC(=C3)C(C)=C2)C)=C(C)C(C=C)=C1C=C1C(C)=C(CC)C3=N1 KWVYZVYHZCFYIY-UHFFFAOYSA-N 0.000 abstract 4
- 150000003839 salts Chemical class 0.000 abstract 4
- 206010028980 Neoplasm Diseases 0.000 abstract 2
- 230000000840 anti-viral effect Effects 0.000 abstract 2
- 238000002622 cytoluminescent therapy Methods 0.000 abstract 2
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/409—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having four such rings, e.g. porphine derivatives, bilirubin, biliverdine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
- A61K41/0076—PDT with expanded (metallo)porphyrins, i.e. having more than 20 ring atoms, e.g. texaphyrins, sapphyrins, hexaphyrins, pentaphyrins, porphocyanines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
- A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
- A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
- A61K49/0036—Porphyrins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0613—Apparatus adapted for a specific treatment
- A61N5/062—Photodynamic therapy, i.e. excitation of an agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F3/00—Compounds containing elements of Groups 2 or 12 of the Periodic Table
- C07F3/06—Zinc compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/0658—Radiation therapy using light characterised by the wavelength of light used
- A61N2005/0659—Radiation therapy using light characterised by the wavelength of light used infrared
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/0658—Radiation therapy using light characterised by the wavelength of light used
- A61N2005/0662—Visible light
- A61N2005/0663—Coloured light
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Pathology (AREA)
- Radiology & Medical Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Radiation-Therapy Devices (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicinal Preparation (AREA)
Abstract
La presente invención está relacionada con análogos de la filoclorina y sus sales farmacéuticamente aceptables, y con composiciones que comprenden análogos de la filoclorina y sus sales farmacéuticamente aceptables. Los análogos de la filoclorina y sus sales farmacéuticamente aceptables son adecuados para el uso en el tratamiento fotodinámico, tratamiento citoluminiscente y diagnóstico fotodinámico, por ejemplo, para tratar o detectar un tumor, o para el tratamiento antiviral. La presente invención también está relacionada con el uso de análogos de la filoclorina y sus sales farmacéuticamente aceptables en la fabricación de un agente fototerapéutico o de fotodiagnóstico y con un método de tratamiento fotodinámico, tratamiento citoluminiscente y diagnóstico fotodinámico, por ejemplo, para tratar o detectar un tumor, o para el tratamiento antiviral. (ver Fórmulas).
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB2018667.2A GB202018667D0 (en) | 2020-11-26 | 2020-11-26 | Photodynamic therapy and diagnosis |
PCT/EP2021/083253 WO2022112537A1 (en) | 2020-11-26 | 2021-11-26 | Photodynamic therapy and diagnosis |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2023006205A true MX2023006205A (es) | 2023-07-20 |
Family
ID=74099827
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2023006205A MX2023006205A (es) | 2020-11-26 | 2021-11-26 | Tratamiento y diagnostico fotodinamico. |
Country Status (11)
Country | Link |
---|---|
US (1) | US20230365577A1 (es) |
EP (1) | EP4251627A1 (es) |
JP (1) | JP2023552740A (es) |
KR (1) | KR20230147042A (es) |
CN (1) | CN116724043A (es) |
AU (1) | AU2021388872C1 (es) |
CA (1) | CA3199991A1 (es) |
GB (1) | GB202018667D0 (es) |
IL (1) | IL303068A (es) |
MX (1) | MX2023006205A (es) |
WO (1) | WO2022112537A1 (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB202217864D0 (en) * | 2022-11-28 | 2023-01-11 | Rmw Cho Group Ltd | Novel compounds |
GB202217863D0 (en) * | 2022-11-28 | 2023-01-11 | Rmw Cho Group Ltd | Novel compounds |
WO2024115524A1 (en) * | 2022-11-28 | 2024-06-06 | Rmw Cho Group Limited | Porphyrin and phosphonium-porphyrin based compounds for photodynamic therapy and diagnostics |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0323358D0 (en) * | 2003-10-06 | 2003-11-05 | Green Grass Design Ltd | Novel compounds and processes |
AU2013357030B2 (en) * | 2012-12-14 | 2018-03-29 | Rmw Cho Group Limited | Chlorin derivative useful in photodynamic therapy and diagnosis |
US9951081B1 (en) * | 2016-10-26 | 2018-04-24 | Hui Liu | Chlorin e6 derivative and pharmaceutically acceptable salt thereof and process for preparing and use of the same |
-
2020
- 2020-11-26 GB GBGB2018667.2A patent/GB202018667D0/en not_active Ceased
-
2021
- 2021-11-26 JP JP2023532650A patent/JP2023552740A/ja active Pending
- 2021-11-26 IL IL303068A patent/IL303068A/en unknown
- 2021-11-26 MX MX2023006205A patent/MX2023006205A/es unknown
- 2021-11-26 WO PCT/EP2021/083253 patent/WO2022112537A1/en active Application Filing
- 2021-11-26 AU AU2021388872A patent/AU2021388872C1/en active Active
- 2021-11-26 KR KR1020237021260A patent/KR20230147042A/ko unknown
- 2021-11-26 EP EP21823794.9A patent/EP4251627A1/en active Pending
- 2021-11-26 CN CN202180079052.0A patent/CN116724043A/zh active Pending
- 2021-11-26 CA CA3199991A patent/CA3199991A1/en active Pending
-
2023
- 2023-05-18 US US18/320,082 patent/US20230365577A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
AU2021388872C1 (en) | 2023-06-22 |
CN116724043A (zh) | 2023-09-08 |
KR20230147042A (ko) | 2023-10-20 |
AU2021388872A1 (en) | 2022-09-22 |
GB202018667D0 (en) | 2021-01-13 |
IL303068A (en) | 2023-07-01 |
AU2021388872B2 (en) | 2023-03-16 |
EP4251627A1 (en) | 2023-10-04 |
JP2023552740A (ja) | 2023-12-19 |
WO2022112537A1 (en) | 2022-06-02 |
CA3199991A1 (en) | 2022-06-02 |
US20230365577A1 (en) | 2023-11-16 |
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