MX2023003197A - Formulacion farmaceutica acuosa de fosfato sodico de hidrocortisona y monotioglicerol. - Google Patents
Formulacion farmaceutica acuosa de fosfato sodico de hidrocortisona y monotioglicerol.Info
- Publication number
- MX2023003197A MX2023003197A MX2023003197A MX2023003197A MX2023003197A MX 2023003197 A MX2023003197 A MX 2023003197A MX 2023003197 A MX2023003197 A MX 2023003197A MX 2023003197 A MX2023003197 A MX 2023003197A MX 2023003197 A MX2023003197 A MX 2023003197A
- Authority
- MX
- Mexico
- Prior art keywords
- monothioglycerol
- sodium phosphate
- pharmaceutical formulation
- aqueous pharmaceutical
- hydrocortisone sodium
- Prior art date
Links
- BGSOJVFOEQLVMH-VWUMJDOOSA-N cortisol phosphate Chemical compound O=C1CC[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)COP(O)(O)=O)[C@@H]4[C@@H]3CCC2=C1 BGSOJVFOEQLVMH-VWUMJDOOSA-N 0.000 title abstract 2
- 229960004204 hydrocortisone sodium phosphate Drugs 0.000 title abstract 2
- PJUIMOJAAPLTRJ-UHFFFAOYSA-N monothioglycerol Chemical compound OCC(O)CS PJUIMOJAAPLTRJ-UHFFFAOYSA-N 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 238000009472 formulation Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Inorganic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063081164P | 2020-09-21 | 2020-09-21 | |
| PCT/US2021/051349 WO2022061303A1 (en) | 2020-09-21 | 2021-09-21 | Aqueous pharmaceutical formulation of hydrocortisone sodium phosphate and monothioglycerol |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2023003197A true MX2023003197A (es) | 2023-08-04 |
Family
ID=80775681
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2023003197A MX2023003197A (es) | 2020-09-21 | 2021-09-21 | Formulacion farmaceutica acuosa de fosfato sodico de hidrocortisona y monotioglicerol. |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US20220096496A1 (enExample) |
| EP (1) | EP4213827A4 (enExample) |
| JP (1) | JP2023542345A (enExample) |
| KR (1) | KR20230104131A (enExample) |
| CN (1) | CN116367835A (enExample) |
| AU (1) | AU2021345429A1 (enExample) |
| CA (1) | CA3192530A1 (enExample) |
| IL (1) | IL301352A (enExample) |
| MX (1) | MX2023003197A (enExample) |
| WO (1) | WO2022061303A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023183807A1 (en) * | 2022-03-21 | 2023-09-28 | Antares Pharma, Inc. | Aqueous pharmaceutical formulation of hydrocortisone sodium phosphate and monothioglycerol |
| US11904046B1 (en) | 2022-11-14 | 2024-02-20 | Eton Pharmaceuticals, Inc. | Hydrocortisone oral liquid formulations |
| WO2024214110A1 (en) * | 2023-04-08 | 2024-10-17 | Cipla Limited | A safe pharmaceutical composition of hydrocortisone |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA911885A (en) * | 1972-10-10 | Gruppo Lepetit S.P.A. | Stable aqueous steroid phosphate solutions | |
| US2970944A (en) | 1958-04-04 | 1961-02-07 | Merck & Co Inc | Parenteral solutions of steroid phosphates stabilized with creatinines |
| IL34366A (en) * | 1969-05-07 | 1973-06-29 | Lepetit Spa | Stable aqueous 21-hydroxy steroid phosphate solutions |
| US5173488A (en) | 1989-08-21 | 1992-12-22 | American Cyanamid Company | Stable injectable pharmaceutical formulation for folic acid and leucovorin salts and method |
| US5733572A (en) * | 1989-12-22 | 1998-03-31 | Imarx Pharmaceutical Corp. | Gas and gaseous precursor filled microspheres as topical and subcutaneous delivery vehicles |
| WO1995006112A1 (en) * | 1993-08-23 | 1995-03-02 | Baxter International Inc. | In vitro growth of neutrophil and megakaryocyte precursors in serum-free media |
| US6090800A (en) * | 1997-05-06 | 2000-07-18 | Imarx Pharmaceutical Corp. | Lipid soluble steroid prodrugs |
| US20020039594A1 (en) * | 1997-05-13 | 2002-04-04 | Evan C. Unger | Solid porous matrices and methods of making and using the same |
| WO2006079064A1 (en) | 2005-01-24 | 2006-07-27 | Antares Pharma, Inc. | Prefilled needle assisted jet injector |
| ZA200804550B (en) * | 2005-11-09 | 2009-08-26 | Combinatorx Inc | Methods, compositions, and kits for the treatment of medical conditions |
| JP5731829B2 (ja) | 2008-03-10 | 2015-06-10 | アンタレス・ファーマ・インコーポレーテッド | 注射器安全装置 |
| AU2010226442A1 (en) | 2009-03-20 | 2011-10-13 | Antares Pharma, Inc. | Hazardous agent injection system |
| WO2014165142A1 (en) | 2013-03-13 | 2014-10-09 | Benjamin Newton | Multiple dosage injector with rotating screw dosage system |
| UA119324C2 (uk) * | 2013-04-02 | 2019-06-10 | Теміс Медікер Лімітед | Композиції фармацевтично активних речовин, що містять моноетиловий ефір діетиленгліколю або інші алкільні похідні |
| ES2673290T3 (es) * | 2016-01-11 | 2018-06-21 | Lamda Laboratories S.A. | Soluciones farmacéuticas orales que contienen fosfato sódico de hidrocortisona |
| FR3047904B1 (fr) | 2016-02-18 | 2018-03-23 | Crossject | Dispositif d’injection sans aiguille a membrane coulissante |
| FR3057775B1 (fr) * | 2016-10-26 | 2018-11-02 | Crossject | Solution pharmaceutique d’hydrocortisone pour dispositif d’injection |
| US11814341B2 (en) * | 2018-05-04 | 2023-11-14 | Ohio State Innovation Foundation | Non-peptidic cell-penetrating motifs |
| JP2022511029A (ja) * | 2018-12-04 | 2022-01-28 | スミトモ ダイニッポン ファーマ オンコロジー， インコーポレイテッド | がんの処置のための薬剤としての使用のためのｃｄｋ９インヒビターおよびその多形 |
-
2021
- 2021-09-21 AU AU2021345429A patent/AU2021345429A1/en active Pending
- 2021-09-21 EP EP21870423.7A patent/EP4213827A4/en active Pending
- 2021-09-21 CN CN202180074582.6A patent/CN116367835A/zh active Pending
- 2021-09-21 MX MX2023003197A patent/MX2023003197A/es unknown
- 2021-09-21 JP JP2023518141A patent/JP2023542345A/ja active Pending
- 2021-09-21 WO PCT/US2021/051349 patent/WO2022061303A1/en not_active Ceased
- 2021-09-21 CA CA3192530A patent/CA3192530A1/en active Pending
- 2021-09-21 IL IL301352A patent/IL301352A/en unknown
- 2021-09-21 KR KR1020237012932A patent/KR20230104131A/ko active Pending
- 2021-10-05 US US17/494,340 patent/US20220096496A1/en not_active Abandoned
-
2022
- 2022-11-18 US US18/056,997 patent/US11857555B2/en active Active
-
2023
- 2023-10-27 US US18/496,559 patent/US20240131035A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20230099165A1 (en) | 2023-03-30 |
| US20240131035A1 (en) | 2024-04-25 |
| IL301352A (en) | 2023-05-01 |
| AU2021345429A1 (en) | 2023-05-04 |
| KR20230104131A (ko) | 2023-07-07 |
| AU2021345429A9 (en) | 2024-08-08 |
| WO2022061303A1 (en) | 2022-03-24 |
| US20220096496A1 (en) | 2022-03-31 |
| JP2023542345A (ja) | 2023-10-06 |
| CA3192530A1 (en) | 2022-03-24 |
| EP4213827A1 (en) | 2023-07-26 |
| EP4213827A4 (en) | 2024-10-23 |
| CN116367835A (zh) | 2023-06-30 |
| US11857555B2 (en) | 2024-01-02 |
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