MX2023002997A - Metodo de tratamiento de la amiloidosis. - Google Patents

Metodo de tratamiento de la amiloidosis.

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Publication number
MX2023002997A
MX2023002997A MX2023002997A MX2023002997A MX2023002997A MX 2023002997 A MX2023002997 A MX 2023002997A MX 2023002997 A MX2023002997 A MX 2023002997A MX 2023002997 A MX2023002997 A MX 2023002997A MX 2023002997 A MX2023002997 A MX 2023002997A
Authority
MX
Mexico
Prior art keywords
subject
treating
disorder
methods
amyloidosis disease
Prior art date
Application number
MX2023002997A
Other languages
English (en)
Inventor
Michael Spector
Susan B Sobolov-Jaynes
Michael Kahsai
Anthony S Lubiniecki
Jessica G Raviwong
Original Assignee
Caelum Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Caelum Biosciences Inc filed Critical Caelum Biosciences Inc
Publication of MX2023002997A publication Critical patent/MX2023002997A/es

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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
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    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • AHUMAN NECESSITIES
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    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
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    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
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  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
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  • Neurology (AREA)
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  • Biophysics (AREA)
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  • Psychiatry (AREA)
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Abstract

En el presente documento se proporcionan métodos para tratar la enfermedad y el trastorno de amiloidosis en un sujeto y métodos para disminuir la cantidad de depósitos de amiloide en un órgano. Los métodos proporcionados en el presente documento incluyen la administración de un anticuerpo, solo o junto con otra terapia. En un aspecto, la divulgación proporciona un método para tratar una enfermedad o un trastorno de amiloidosis en un sujeto, que incluye administrar al sujeto la composición farmacéutica de la invención y una terapia adicional, tratando de esta manera la enfermedad o el trastorno de amiloidosis en el sujeto.
MX2023002997A 2020-09-14 2021-09-14 Metodo de tratamiento de la amiloidosis. MX2023002997A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US202063078258P 2020-09-14 2020-09-14
US202063116100P 2020-11-19 2020-11-19
US202163176015P 2021-04-16 2021-04-16
PCT/US2021/050316 WO2022056484A1 (en) 2020-09-14 2021-09-14 Method of treating amyloidosis

Publications (1)

Publication Number Publication Date
MX2023002997A true MX2023002997A (es) 2023-05-11

Family

ID=80631942

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2023002997A MX2023002997A (es) 2020-09-14 2021-09-14 Metodo de tratamiento de la amiloidosis.

Country Status (9)

Country Link
US (1) US20230364228A1 (es)
EP (1) EP4210753A1 (es)
JP (1) JP2023541191A (es)
KR (1) KR20230069161A (es)
AU (1) AU2021339851A1 (es)
CA (1) CA3192069A1 (es)
IL (1) IL301047A (es)
MX (1) MX2023002997A (es)
WO (1) WO2022056484A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3231073A1 (en) * 2021-09-14 2023-03-23 Michael Spector Method of treating multiple myeloma
WO2024059756A1 (en) * 2022-09-16 2024-03-21 Temple University Of The Commonwealth System Of Higher Education Bag 3 methods and uses for treatment of cardiac amyloidosis

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101370253B1 (ko) * 2004-10-22 2014-03-05 암젠 인크 재조합 항체의 재접힘 방법
US20090028847A1 (en) * 2007-04-12 2009-01-29 Trustees Of Boston University Multiple myeloma and al amyloid immunotherapy targeting immunoglobulin light chains and uses thereof
WO2016189491A1 (en) * 2015-05-28 2016-12-01 Glaxosmithkline Intellectual Property Development Limited Novel formulation
US11382974B2 (en) * 2017-08-01 2022-07-12 The Trustees Of Columbia University In The City Of New York Methods and compositions for treatment of amyloid deposition diseases
CA3132780A1 (en) * 2019-03-05 2020-09-10 Prothena Biosciences Limited Methods of treating al amyloidosis

Also Published As

Publication number Publication date
KR20230069161A (ko) 2023-05-18
AU2021339851A8 (en) 2023-04-20
CA3192069A1 (en) 2022-03-17
JP2023541191A (ja) 2023-09-28
WO2022056484A1 (en) 2022-03-17
EP4210753A1 (en) 2023-07-19
AU2021339851A1 (en) 2023-04-13
IL301047A (en) 2023-05-01
US20230364228A1 (en) 2023-11-16

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