MX2023002997A - Metodo de tratamiento de la amiloidosis. - Google Patents

Metodo de tratamiento de la amiloidosis.

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Publication number
MX2023002997A
MX2023002997A MX2023002997A MX2023002997A MX2023002997A MX 2023002997 A MX2023002997 A MX 2023002997A MX 2023002997 A MX2023002997 A MX 2023002997A MX 2023002997 A MX2023002997 A MX 2023002997A MX 2023002997 A MX2023002997 A MX 2023002997A
Authority
MX
Mexico
Prior art keywords
subject
treating
disorder
methods
amyloidosis disease
Prior art date
Application number
MX2023002997A
Other languages
English (en)
Inventor
Michael Spector
Susan B Sobolov-Jaynes
Michael Kahsai
Anthony S Lubiniecki
Jessica G Raviwong
Original Assignee
Caelum Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Caelum Biosciences Inc filed Critical Caelum Biosciences Inc
Publication of MX2023002997A publication Critical patent/MX2023002997A/es

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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • C07—ORGANIC CHEMISTRY
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
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    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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  • Health & Medical Sciences (AREA)
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  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
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  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
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  • Genetics & Genomics (AREA)
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Abstract

En el presente documento se proporcionan métodos para tratar la enfermedad y el trastorno de amiloidosis en un sujeto y métodos para disminuir la cantidad de depósitos de amiloide en un órgano. Los métodos proporcionados en el presente documento incluyen la administración de un anticuerpo, solo o junto con otra terapia. En un aspecto, la divulgación proporciona un método para tratar una enfermedad o un trastorno de amiloidosis en un sujeto, que incluye administrar al sujeto la composición farmacéutica de la invención y una terapia adicional, tratando de esta manera la enfermedad o el trastorno de amiloidosis en el sujeto.
MX2023002997A 2020-09-14 2021-09-14 Metodo de tratamiento de la amiloidosis. MX2023002997A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US202063078258P 2020-09-14 2020-09-14
US202063116100P 2020-11-19 2020-11-19
US202163176015P 2021-04-16 2021-04-16
PCT/US2021/050316 WO2022056484A1 (en) 2020-09-14 2021-09-14 Method of treating amyloidosis

Publications (1)

Publication Number Publication Date
MX2023002997A true MX2023002997A (es) 2023-05-11

Family

ID=80631942

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2023002997A MX2023002997A (es) 2020-09-14 2021-09-14 Metodo de tratamiento de la amiloidosis.

Country Status (9)

Country Link
US (1) US20230364228A1 (es)
EP (1) EP4210753A1 (es)
JP (1) JP2023541191A (es)
KR (1) KR20230069161A (es)
AU (1) AU2021339851A1 (es)
CA (1) CA3192069A1 (es)
IL (1) IL301047A (es)
MX (1) MX2023002997A (es)
WO (1) WO2022056484A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2022346750A1 (en) * 2021-09-14 2024-04-11 Caelum Biosciences, Inc. Method of treating multiple myeloma
WO2024059756A1 (en) * 2022-09-16 2024-03-21 Temple University Of The Commonwealth System Of Higher Education Bag 3 methods and uses for treatment of cardiac amyloidosis

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5553963B2 (ja) * 2004-10-22 2014-07-23 アムジエン・インコーポレーテツド 組換え抗体をリフォールディングする方法
US20090028847A1 (en) * 2007-04-12 2009-01-29 Trustees Of Boston University Multiple myeloma and al amyloid immunotherapy targeting immunoglobulin light chains and uses thereof
WO2016189491A1 (en) * 2015-05-28 2016-12-01 Glaxosmithkline Intellectual Property Development Limited Novel formulation
US11382974B2 (en) * 2017-08-01 2022-07-12 The Trustees Of Columbia University In The City Of New York Methods and compositions for treatment of amyloid deposition diseases
BR112021017550A2 (pt) * 2019-03-05 2021-11-09 Prothena Biosciences Ltd Métodos de tratamento da amiloidose al

Also Published As

Publication number Publication date
EP4210753A1 (en) 2023-07-19
KR20230069161A (ko) 2023-05-18
US20230364228A1 (en) 2023-11-16
IL301047A (en) 2023-05-01
AU2021339851A1 (en) 2023-04-13
CA3192069A1 (en) 2022-03-17
AU2021339851A8 (en) 2023-04-20
WO2022056484A1 (en) 2022-03-17
JP2023541191A (ja) 2023-09-28

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