MX2023001049A - Composiciones y métodos para tratar infecciones virales. - Google Patents

Composiciones y métodos para tratar infecciones virales.

Info

Publication number
MX2023001049A
MX2023001049A MX2023001049A MX2023001049A MX2023001049A MX 2023001049 A MX2023001049 A MX 2023001049A MX 2023001049 A MX2023001049 A MX 2023001049A MX 2023001049 A MX2023001049 A MX 2023001049A MX 2023001049 A MX2023001049 A MX 2023001049A
Authority
MX
Mexico
Prior art keywords
peptides
nucleic acids
compositions
methods
viral infections
Prior art date
Application number
MX2023001049A
Other languages
English (en)
Spanish (es)
Inventor
Gilles Divita
Neil P Desai
Original Assignee
Aadigen Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aadigen Llc filed Critical Aadigen Llc
Publication of MX2023001049A publication Critical patent/MX2023001049A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1131Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/10Fusion polypeptide containing a localisation/targetting motif containing a tag for extracellular membrane crossing, e.g. TAT or VP22
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/14Type of nucleic acid interfering nucleic acids [NA]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2320/00Applications; Uses
    • C12N2320/30Special therapeutic applications
    • C12N2320/31Combination therapy
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2320/00Applications; Uses
    • C12N2320/30Special therapeutic applications
    • C12N2320/32Special delivery means, e.g. tissue-specific

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Plant Pathology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
MX2023001049A 2020-07-24 2021-07-23 Composiciones y métodos para tratar infecciones virales. MX2023001049A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR2007849 2020-07-24
PCT/US2021/043077 WO2022020782A1 (en) 2020-07-24 2021-07-23 Compositions and methods for treating viral infections

Publications (1)

Publication Number Publication Date
MX2023001049A true MX2023001049A (es) 2023-04-11

Family

ID=77398656

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2023001049A MX2023001049A (es) 2020-07-24 2021-07-23 Composiciones y métodos para tratar infecciones virales.

Country Status (8)

Country Link
US (1) US20230304010A1 (enExample)
EP (1) EP4185602A1 (enExample)
JP (1) JP2023536436A (enExample)
CN (1) CN116724059A (enExample)
AU (1) AU2021314336A1 (enExample)
CA (1) CA3190101A1 (enExample)
MX (1) MX2023001049A (enExample)
WO (1) WO2022020782A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3955967A4 (en) 2019-04-17 2023-06-07 Aadigen, LLC PEPTIDES AND NANOPARTICLES FOR INTRACELLULAR DELIVERY OF MOLECULES
WO2024187121A1 (en) * 2023-03-08 2024-09-12 Red Queen Therapeutics, Inc. Combination therapies comprising stabilized sars-cov-2 peptides
WO2024187174A2 (en) 2023-03-09 2024-09-12 Aadigen, Llc Compositions for treating cancer with kras mutations and uses thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050113298A1 (en) * 2003-09-15 2005-05-26 The Brigham And Women's Hospital, Inc. Receptor binding peptides derived from the SARS S protein
US7514530B2 (en) 2004-04-26 2009-04-07 Centre National De La Recherche Scientifique Peptide carrier for delivering siRNA into mammalian cells
US7579318B2 (en) 2005-12-06 2009-08-25 Centre De La Recherche De La Scientifique Cell penetrating peptides for intracellular delivery of molecules
WO2012137036A1 (en) 2011-04-04 2012-10-11 Centre National De La Recherche Scientifique Cell penetrating peptides for intracellular delivery of molecules
WO2014053880A1 (en) 2012-10-04 2014-04-10 Centre National De La Recherche Scientifique Cell penetrating peptides for intracellular delivery of molecules
WO2014053881A1 (en) 2012-10-04 2014-04-10 Centre National De La Recherche Scientifique Cell penetrating peptides for intracellular delivery of molecules
WO2014053879A1 (en) 2012-10-04 2014-04-10 Centre National De La Recherche Scientifique Cell penetrating peptides for intracellular delivery of molecules
WO2014053882A1 (en) 2012-10-04 2014-04-10 Centre National De La Recherche Scientifique Cell penetrating peptides for intracellular delivery of molecules
MX387665B (es) 2014-12-24 2025-03-18 Aadigen Llc Péptidos, complejos, moléculas de carga y nanopartículas que contienen los mismos.
CA3025523A1 (en) * 2016-05-27 2017-11-30 Aadigen, Llc Peptides and nanoparticles for intracellular delivery of genome-editing molecules
AU2018313940A1 (en) * 2017-08-10 2020-03-05 Aadigen, Llc Peptides and nanoparticles for intracellular delivery of virus

Also Published As

Publication number Publication date
US20230304010A1 (en) 2023-09-28
AU2021314336A1 (en) 2023-03-09
WO2022020782A1 (en) 2022-01-27
JP2023536436A (ja) 2023-08-25
CN116724059A (zh) 2023-09-08
CA3190101A1 (en) 2022-01-27
EP4185602A1 (en) 2023-05-31

Similar Documents

Publication Publication Date Title
MX2023001049A (es) Composiciones y métodos para tratar infecciones virales.
EP4445902A3 (en) Diacylglycerol kinase modulating compounds
EA202092808A1 (ru) Вакцины на основе наночастиц с новыми структурными компонентами
WO2021046549A8 (en) Compositions and methods for the treatment of viral infections
WO2020252393A8 (en) Compositions and methods for the treatment of human immunodeficiency virus
PH12021550822A1 (en) Compositions and methods for the treatment of viral infections
WO2017019891A3 (en) Compositions and methods for silencing hepatitis b virus gene expression
SG195194A1 (en) Nanogels
PH12022552125A1 (en) Stabilized soluble pre-fusion rsv f proteins
WO2016183366A3 (en) Compositions and methods for silencing expression of hepatitis d virus rna
WO2017156311A3 (en) Combination vectors and methods for treating cancer
MX2022014598A (es) Anticuerpos anti-glicoproteína espicular sars-cov-2 y fragmentos de unión al antígeno.
EP4567109A3 (en) Optimized engineered meganucleases having specificity for a recognition sequence in the hepatitis b virus genome
WO2021046398A3 (en) Combination antiviral therapy for measles
WO2009120339A3 (en) Vectors for delivering disease neutralizing agents
MX2021012604A (es) Nuevo inhibidor de mek para el tratamiento de infecciones virales y bacterianas.
ZA202202180B (en) Engineered hcv e2 immunogens and related vaccine compositions
WO2008064072A3 (en) Anti-tsg101 antibodies and their uses for treatment of viral infections
WO2023021098A3 (en) Pharmaceutical composition comprising nanoparticles for the targeted delivery of antigens
WO2021061707A8 (en) Compositions and methods for modulating apolipoprotein b (apob) gene expression
MX2019013874A (es) Peptidos y sus usos como agentes antivirales.
PH12022550240A1 (en) Genetically engineered oncolytic vaccinia viruses and methods of uses thereof
WO2020053742A3 (en) Anti-hla-hbv peptide antibodies
WO2023150375A3 (en) Methods and compositions for treating covid infections
WO2021081515A3 (en) Compositions and methods for the treatment of human immunodeficiency virus