MX2023000198A - Inhibidores de atr y usos de estos. - Google Patents
Inhibidores de atr y usos de estos.Info
- Publication number
- MX2023000198A MX2023000198A MX2023000198A MX2023000198A MX2023000198A MX 2023000198 A MX2023000198 A MX 2023000198A MX 2023000198 A MX2023000198 A MX 2023000198A MX 2023000198 A MX2023000198 A MX 2023000198A MX 2023000198 A MX2023000198 A MX 2023000198A
- Authority
- MX
- Mexico
- Prior art keywords
- atr inhibitors
- compounds
- pharmaceutical compositions
- inhibitors
- atr
- Prior art date
Links
- 239000003112 inhibitor Substances 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 102000001253 Protein Kinase Human genes 0.000 abstract 1
- 108060006633 protein kinase Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
La presente divulgación se refiere a nuevos compuestos útiles como inhibidores de la cinasa ATR, así como a composiciones farmacéuticas que comprenden estos compuestos y métodos de tratamiento mediante la administración de estos compuestos o las composiciones farmacéuticas.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2020100088 | 2020-07-03 | ||
| CN2020110396 | 2020-08-21 | ||
| CN2020134732 | 2020-12-09 | ||
| CN2020135604 | 2020-12-11 | ||
| PCT/CN2021/104232 WO2022002245A1 (en) | 2020-07-03 | 2021-07-02 | Atr inhibitors and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2023000198A true MX2023000198A (es) | 2023-02-22 |
Family
ID=79317475
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2023000198A MX2023000198A (es) | 2020-07-03 | 2021-07-02 | Inhibidores de atr y usos de estos. |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20230339927A1 (es) |
| EP (1) | EP4175948A4 (es) |
| JP (1) | JP2023532303A (es) |
| KR (1) | KR20230035070A (es) |
| CN (1) | CN116134022A (es) |
| AU (1) | AU2021302146A1 (es) |
| BR (1) | BR112022024700A2 (es) |
| CA (1) | CA3185491A1 (es) |
| CO (1) | CO2023000858A2 (es) |
| IL (1) | IL299510A (es) |
| MX (1) | MX2023000198A (es) |
| TW (1) | TW202216701A (es) |
| WO (1) | WO2022002245A1 (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023131234A1 (en) * | 2022-01-06 | 2023-07-13 | Shanghai Antengene Corporation Limited | Crystalline forms of an atr inhibitor |
| WO2024182551A1 (en) * | 2023-03-01 | 2024-09-06 | Uereka Biosciences, Inc. | Lzk inhibitors |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI700283B (zh) * | 2014-08-04 | 2020-08-01 | 德商拜耳製藥公司 | ２-(嗎啉-４-基)-１,７-萘啶 |
| US11690911B2 (en) * | 2017-08-04 | 2023-07-04 | Bayer Aktiengesellschaft | Combination of ATR kinase inhibitors and PD-1/PD-L1 inhibitors |
| CA3090330A1 (en) * | 2018-02-07 | 2019-08-15 | Shijiazhuang Sagacity New Drug Development Co., Ltd. | Atr inhibitor and application thereof |
| CA3111878A1 (en) * | 2018-09-07 | 2020-03-12 | Merck Patent Gmbh | 5-morpholin-4-yl-pyrazolo[4,3-b]pyridine derivatives |
-
2021
- 2021-07-02 US US18/014,178 patent/US20230339927A1/en active Pending
- 2021-07-02 EP EP21834378.8A patent/EP4175948A4/en not_active Withdrawn
- 2021-07-02 BR BR112022024700A patent/BR112022024700A2/pt not_active Application Discontinuation
- 2021-07-02 MX MX2023000198A patent/MX2023000198A/es unknown
- 2021-07-02 KR KR1020237003732A patent/KR20230035070A/ko unknown
- 2021-07-02 AU AU2021302146A patent/AU2021302146A1/en active Pending
- 2021-07-02 JP JP2022580916A patent/JP2023532303A/ja active Pending
- 2021-07-02 CN CN202180057399.5A patent/CN116134022A/zh active Pending
- 2021-07-02 CA CA3185491A patent/CA3185491A1/en active Pending
- 2021-07-02 TW TW110124500A patent/TW202216701A/zh unknown
- 2021-07-02 WO PCT/CN2021/104232 patent/WO2022002245A1/en active Application Filing
- 2021-07-02 IL IL299510A patent/IL299510A/en unknown
-
2023
- 2023-01-26 CO CONC2023/0000858A patent/CO2023000858A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL299510A (en) | 2023-02-01 |
| EP4175948A1 (en) | 2023-05-10 |
| JP2023532303A (ja) | 2023-07-27 |
| CN116134022A (zh) | 2023-05-16 |
| EP4175948A4 (en) | 2024-07-17 |
| AU2021302146A1 (en) | 2023-01-19 |
| BR112022024700A2 (pt) | 2023-12-05 |
| TW202216701A (zh) | 2022-05-01 |
| KR20230035070A (ko) | 2023-03-10 |
| US20230339927A1 (en) | 2023-10-26 |
| CO2023000858A2 (es) | 2023-02-16 |
| CA3185491A1 (en) | 2022-01-06 |
| WO2022002245A1 (en) | 2022-01-06 |
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