MX2022007715A - Gaboxadol para el tratamiento terapeutico del sindrome de delecion 1p36. - Google Patents
Gaboxadol para el tratamiento terapeutico del sindrome de delecion 1p36.Info
- Publication number
- MX2022007715A MX2022007715A MX2022007715A MX2022007715A MX2022007715A MX 2022007715 A MX2022007715 A MX 2022007715A MX 2022007715 A MX2022007715 A MX 2022007715A MX 2022007715 A MX2022007715 A MX 2022007715A MX 2022007715 A MX2022007715 A MX 2022007715A
- Authority
- MX
- Mexico
- Prior art keywords
- gaboxadol
- therapeutic treatment
- deletion syndrome
- deletion
- syndrome
- Prior art date
Links
- 208000026120 1p36 deletion syndrome Diseases 0.000 title abstract 2
- ZXRVKCBLGJOCEE-UHFFFAOYSA-N Gaboxadol Chemical compound C1NCCC2=C1ONC2=O ZXRVKCBLGJOCEE-UHFFFAOYSA-N 0.000 title abstract 2
- 201000004723 chromosome 1p36 deletion syndrome Diseases 0.000 title abstract 2
- 229950004346 gaboxadol Drugs 0.000 title abstract 2
- 230000001225 therapeutic effect Effects 0.000 title 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962949551P | 2019-12-18 | 2019-12-18 | |
| PCT/US2020/065801 WO2021127308A1 (en) | 2019-12-18 | 2020-12-18 | GABOXADOL FOR THERAPEUTIC TREATMENT OF 1p36 DELETION SYNDROME |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2022007715A true MX2022007715A (es) | 2022-07-19 |
Family
ID=76439052
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2022007715A MX2022007715A (es) | 2019-12-18 | 2020-12-18 | Gaboxadol para el tratamiento terapeutico del sindrome de delecion 1p36. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US11364228B2 (https=) |
| EP (1) | EP4051272A4 (https=) |
| JP (1) | JP2023507764A (https=) |
| KR (1) | KR20220114572A (https=) |
| CN (1) | CN114786669A (https=) |
| AU (1) | AU2020405060A1 (https=) |
| CA (1) | CA3164635A1 (https=) |
| IL (1) | IL293924A (https=) |
| MX (1) | MX2022007715A (https=) |
| WO (1) | WO2021127308A1 (https=) |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19525598C2 (de) | 1995-07-13 | 1997-09-25 | Max Planck Gesellschaft | Schlafmittel |
| AR031473A1 (es) | 2000-11-20 | 2003-09-24 | Lundbeck & Co As H | Intensificadores de gaba en el tratamiento de enfermedades relacionadas con una reducida actividad neuroesteroide |
| US20020165217A1 (en) | 2001-05-01 | 2002-11-07 | Pfizer Inc. | Combination treatment for anxiety and depression |
| BRPI0410857A (pt) | 2003-06-25 | 2006-07-04 | Lundbeck & Co As H | método para o tratamento de depressão, uso de gaboxadol, e, composição farmacêutica |
| US20050234093A1 (en) | 2003-06-25 | 2005-10-20 | H. Lundbeck A/S | Treatment of depression and other affective disorders |
| US20070032553A1 (en) | 2003-09-10 | 2007-02-08 | Mckernan Ruth | Use of gabaa receptor agonists for the treatment of hearing, vestibular and attention disorders, intention tremor and restless leg syndrome |
| TW200528098A (en) | 2003-12-18 | 2005-09-01 | Lundbeck & Co As H | Treatment of insomnia in human patients |
| US20050137222A1 (en) | 2003-12-18 | 2005-06-23 | H. Lundbeck A/S | Treatment of insomnia in human patients |
| GB0402118D0 (en) | 2004-01-30 | 2004-03-03 | Merck Sharp & Dohme | Polymorphic forms of a GABAA agonist |
| JP2007530604A (ja) | 2004-04-02 | 2007-11-01 | ハー・ルンドベック・アクチエゼルスカベット | 呼吸機能障害の治療 |
| GB0417558D0 (en) | 2004-08-06 | 2004-09-08 | Merck Sharp & Dohme | Novel combination therapy |
| EP1848420A4 (en) | 2005-01-28 | 2008-01-23 | Merck & Co Inc | POLYMORPH SHAPES OF A GABAA AGONIST |
| US20080262029A1 (en) | 2005-04-29 | 2008-10-23 | H. Lundbeck A/S | Acid and Base Salt Forms of Gaboxadol |
| DE102005020882A1 (de) | 2005-05-04 | 2006-11-09 | Dömling, Alexander, Dr. | Verwendung von Gaboxadol und Derivaten zur Behandlung von Kinase-induzierten Krankheiten |
| US20110046090A1 (en) | 2005-10-31 | 2011-02-24 | Braincells Inc. | Modulation of neurogenesis with gaba agents and gaba analogs |
| AU2006308889A1 (en) | 2005-10-31 | 2007-05-10 | Braincells, Inc. | GABA receptor mediated modulation of neurogenesis |
| US20090269795A1 (en) | 2007-03-09 | 2009-10-29 | The Research Foundation Of State University Of New York | Mutant alpha4betadelta GABAA receptor and methods of treating anxiety or irritability |
| US20090048288A1 (en) | 2007-08-13 | 2009-02-19 | H. Lundbeck A/S | Method of treating stress-mediated depression |
| TW200920358A (en) | 2007-08-13 | 2009-05-16 | Lundbeck & Co As H | Method of treating stress-mediated depression |
| US20090143335A1 (en) | 2007-10-29 | 2009-06-04 | H. Lundbeck A/S | Modified absorption formulation of gaboxadol |
| WO2010015037A1 (en) | 2008-08-08 | 2010-02-11 | Howard Florey Institute | Therapeutic methods and compositions |
| EP2334299A1 (en) | 2008-09-01 | 2011-06-22 | H. Lundbeck A/S | Pharmaceutical composition comprising gaboxadol and an inhibitor of patl or oat |
| WO2014123909A1 (en) | 2013-02-05 | 2014-08-14 | University Of Washington Through Its Center For Commercialization | Positive allosteric modulators of the gaba-a receptor in the treatment of autism |
| EP3129506A4 (en) * | 2014-04-09 | 2017-12-27 | Lineagen, Inc. | Genetic markers associated with chromosomal deletion and duplication syndromes |
| RS62007B1 (sr) | 2014-06-06 | 2021-07-30 | Ovid Therapeutics Inc | Postupci pojačavanja tonične inhibicije i lečenja angelmanovog sindroma |
| US9682069B2 (en) | 2015-07-17 | 2017-06-20 | Ovid Therapeutics Inc | Methods of treating Dravet syndrome |
| US20170348232A1 (en) | 2016-06-07 | 2017-12-07 | Ovid Therapeutics Inc. | Formulations of gaboxadol for treatment of angelman syndrome, fragile x syndrome and fragile x-associated tremor/ataxia syndrome |
| EP4541420A3 (en) * | 2015-07-17 | 2025-06-25 | Ovid Therapeutics Inc. | Methods of treating developmental disorders with gaboxadol |
| US9399034B1 (en) | 2015-08-11 | 2016-07-26 | Ovid Therapeutics Inc | Methods of sedation during critical care treatment |
| EP3481387A4 (en) | 2016-08-11 | 2020-04-08 | Ovid Therapeutics Inc | METHOD AND COMPOSITIONS FOR TREATING EPILEPTIC DISEASES |
| US10071083B2 (en) * | 2017-02-03 | 2018-09-11 | Ovid Therapeutics Inc | Use of gaboxadol in the treatment of tinnitus |
| JP2020529440A (ja) | 2017-08-04 | 2020-10-08 | オービッド・セラピューティクス・インコーポレイテッドOvid Therapeutics Inc. | 糖尿病および関連する状態の処置におけるガボキサドールの使用 |
-
2020
- 2020-12-18 US US17/126,168 patent/US11364228B2/en active Active
- 2020-12-18 WO PCT/US2020/065801 patent/WO2021127308A1/en not_active Ceased
- 2020-12-18 CN CN202080085811.XA patent/CN114786669A/zh active Pending
- 2020-12-18 AU AU2020405060A patent/AU2020405060A1/en not_active Abandoned
- 2020-12-18 KR KR1020227022608A patent/KR20220114572A/ko not_active Withdrawn
- 2020-12-18 EP EP20901747.4A patent/EP4051272A4/en active Pending
- 2020-12-18 MX MX2022007715A patent/MX2022007715A/es unknown
- 2020-12-18 JP JP2022537866A patent/JP2023507764A/ja active Pending
- 2020-12-18 CA CA3164635A patent/CA3164635A1/en active Pending
- 2020-12-18 IL IL293924A patent/IL293924A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2021127308A1 (en) | 2021-06-24 |
| CN114786669A (zh) | 2022-07-22 |
| KR20220114572A (ko) | 2022-08-17 |
| EP4051272A4 (en) | 2023-01-04 |
| US20210186938A1 (en) | 2021-06-24 |
| CA3164635A1 (en) | 2021-06-24 |
| US11364228B2 (en) | 2022-06-21 |
| IL293924A (en) | 2022-08-01 |
| EP4051272A1 (en) | 2022-09-07 |
| JP2023507764A (ja) | 2023-02-27 |
| AU2020405060A1 (en) | 2022-06-09 |
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