MX2022005362A - Composiciones de trem para codones con-raros y usos relacionados. - Google Patents
Composiciones de trem para codones con-raros y usos relacionados.Info
- Publication number
- MX2022005362A MX2022005362A MX2022005362A MX2022005362A MX2022005362A MX 2022005362 A MX2022005362 A MX 2022005362A MX 2022005362 A MX2022005362 A MX 2022005362A MX 2022005362 A MX2022005362 A MX 2022005362A MX 2022005362 A MX2022005362 A MX 2022005362A
- Authority
- MX
- Mexico
- Prior art keywords
- con
- trem
- compositions
- rare codons
- related uses
- Prior art date
Links
- 108020004705 Codon Proteins 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title 1
- 239000012636 effector Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Cosmetics (AREA)
- Detergent Compositions (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962930361P | 2019-11-04 | 2019-11-04 | |
| PCT/US2020/058948 WO2021092064A1 (en) | 2019-11-04 | 2020-11-04 | Trem compositions for con-rare codons and related uses |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2022005362A true MX2022005362A (es) | 2022-09-23 |
Family
ID=73654885
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2022005362A MX2022005362A (es) | 2019-11-04 | 2020-11-04 | Composiciones de trem para codones con-raros y usos relacionados. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20220364092A1 (enExample) |
| EP (1) | EP4055163A1 (enExample) |
| JP (1) | JP2023500116A (enExample) |
| KR (1) | KR20220128611A (enExample) |
| CN (1) | CN115003810A (enExample) |
| AU (1) | AU2020379762A1 (enExample) |
| CA (1) | CA3160097A1 (enExample) |
| MX (1) | MX2022005362A (enExample) |
| WO (1) | WO2021092064A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102930465B1 (ko) | 2017-11-02 | 2026-02-25 | 더 위스타 인스티튜트 오브 아나토미 앤드 바이올로지 | ACE-tRNA를 이용한 유전 재할당을 통한 정지 코돈의 구조 방법 |
| WO2021243301A2 (en) * | 2020-05-29 | 2021-12-02 | Flagship Pioneering Innovations Vi, Llc. | Trem compositions and methods relating thereto |
| KR20230029685A (ko) * | 2020-05-29 | 2023-03-03 | 플래그쉽 파이어니어링 이노베이션스 브이아이, 엘엘씨 | Trem 조성물 및 이에 관련된 방법 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5801030A (en) | 1995-09-01 | 1998-09-01 | Genvec, Inc. | Methods and vectors for site-specific recombination |
| US6693086B1 (en) | 1998-06-25 | 2004-02-17 | National Jewish Medical And Research Center | Systemic immune activation method using nucleic acid-lipid complexes |
| WO2006105038A2 (en) * | 2005-03-25 | 2006-10-05 | The Uab Research Foundation | Methods of altering gene expression and methods of treatment utilizing same |
| GB0600948D0 (en) * | 2006-01-18 | 2006-02-22 | Univ Dundee | Prevention/Treatment Of Ichthyosis Vulgaris, Atopy And Other Disorders |
| US20120077224A1 (en) * | 2009-06-05 | 2012-03-29 | The Salk Institute For Biological Studies | unnatural amino acid incorporation in eukaryotic cells |
| WO2012006551A2 (en) * | 2010-07-08 | 2012-01-12 | The Brigham And Women's Hospital, Inc. | Neuroprotective molecules and methods of treating neurological disorders and inducing stress granules |
| AU2013327059B2 (en) * | 2012-10-02 | 2018-11-08 | Vaxiion Therapeutics, Llc | Immunomodulatory minicells and methods of use |
| CA2930665A1 (en) | 2013-11-18 | 2015-05-21 | Rubius Therapeutics, Inc. | Synthetic membrane-receiver complexes |
| MA39819A (fr) | 2014-04-01 | 2017-02-08 | Rubius Therapeutics Inc | Méthodes et compositions d'immunomodulation |
| US20180135012A1 (en) | 2015-05-13 | 2018-05-17 | Rubius Therapeutics, Inc. | Membrane-receiver complex therapeutics |
| SI3402491T1 (sl) | 2016-01-11 | 2022-05-31 | Rubius Therapeutics, Inc. | Sestavki in postopki v zvezi z multimodalnimi terapevtskimi celičnimi sistemi za indikacije raka |
| MX2019000205A (es) | 2016-07-07 | 2019-09-23 | Rubius Therapeutics Inc | Composiciones y metodos relacionados con sistemas celulares terapeuticos que expresan arn exogeno. |
| US20180153989A1 (en) | 2016-12-02 | 2018-06-07 | Rubius Therapeutics, Inc. | Compositions and methods related to cell systems for penetrating solid tumors |
| CN110520522A (zh) | 2017-02-17 | 2019-11-29 | 鲁比厄斯治疗法股份有限公司 | 功能化红系细胞 |
| CA3062426A1 (en) | 2017-05-08 | 2018-11-15 | Flagship Pioneering Innovations V, Inc. | Compositions for facilitating membrane fusion and uses thereof |
| WO2020069199A1 (en) * | 2018-09-26 | 2020-04-02 | Case Western Reserve University | Methods and compositions for increasing protein expression and/or treating a haploinsufficiency disorder |
| CA3125567A1 (en) * | 2019-01-18 | 2020-07-23 | Flagship Pioneering, Inc. | Trem compositions and uses thereof |
| WO2020243560A1 (en) * | 2019-05-31 | 2020-12-03 | Flagship Pioneering, Inc. | Uses of trem compositions to modulate trna pools |
-
2020
- 2020-11-04 CA CA3160097A patent/CA3160097A1/en active Pending
- 2020-11-04 US US17/774,410 patent/US20220364092A1/en active Pending
- 2020-11-04 AU AU2020379762A patent/AU2020379762A1/en active Pending
- 2020-11-04 EP EP20817113.2A patent/EP4055163A1/en active Pending
- 2020-11-04 KR KR1020227018837A patent/KR20220128611A/ko active Pending
- 2020-11-04 MX MX2022005362A patent/MX2022005362A/es unknown
- 2020-11-04 WO PCT/US2020/058948 patent/WO2021092064A1/en not_active Ceased
- 2020-11-04 CN CN202080077056.0A patent/CN115003810A/zh active Pending
- 2020-11-04 JP JP2022525706A patent/JP2023500116A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN115003810A (zh) | 2022-09-02 |
| JP2023500116A (ja) | 2023-01-04 |
| KR20220128611A (ko) | 2022-09-21 |
| WO2021092064A1 (en) | 2021-05-14 |
| AU2020379762A1 (en) | 2022-05-26 |
| US20220364092A1 (en) | 2022-11-17 |
| CA3160097A1 (en) | 2021-05-14 |
| EP4055163A1 (en) | 2022-09-14 |
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