MX2022004257A - Composicion farmaceutica y metodo para tratamiento de los trastornos convulsionales. - Google Patents
Composicion farmaceutica y metodo para tratamiento de los trastornos convulsionales.Info
- Publication number
- MX2022004257A MX2022004257A MX2022004257A MX2022004257A MX2022004257A MX 2022004257 A MX2022004257 A MX 2022004257A MX 2022004257 A MX2022004257 A MX 2022004257A MX 2022004257 A MX2022004257 A MX 2022004257A MX 2022004257 A MX2022004257 A MX 2022004257A
- Authority
- MX
- Mexico
- Prior art keywords
- cannabidiol
- cbd
- treatment
- seizure disorders
- transdermal compositions
- Prior art date
Links
- QHMBSVQNZZTUGM-UHFFFAOYSA-N Trans-Cannabidiol Natural products OC1=CC(CCCCC)=CC(O)=C1C1C(C(C)=C)CCC(C)=C1 QHMBSVQNZZTUGM-UHFFFAOYSA-N 0.000 title abstract 5
- QHMBSVQNZZTUGM-ZWKOTPCHSA-N cannabidiol Chemical compound OC1=CC(CCCCC)=CC(O)=C1[C@H]1[C@H](C(C)=C)CCC(C)=C1 QHMBSVQNZZTUGM-ZWKOTPCHSA-N 0.000 title abstract 5
- 229950011318 cannabidiol Drugs 0.000 title abstract 5
- ZTGXAWYVTLUPDT-UHFFFAOYSA-N cannabidiol Natural products OC1=CC(CCCCC)=CC(O)=C1C1C(C(C)=C)CC=C(C)C1 ZTGXAWYVTLUPDT-UHFFFAOYSA-N 0.000 title abstract 5
- PCXRACLQFPRCBB-ZWKOTPCHSA-N dihydrocannabidiol Natural products OC1=CC(CCCCC)=CC(O)=C1[C@H]1[C@H](C(C)C)CCC(C)=C1 PCXRACLQFPRCBB-ZWKOTPCHSA-N 0.000 title abstract 5
- 206010015037 epilepsy Diseases 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title abstract 2
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 abstract 3
- SVTBMSDMJJWYQN-UHFFFAOYSA-N 2-methylpentane-2,4-diol Chemical compound CC(O)CC(C)(C)O SVTBMSDMJJWYQN-UHFFFAOYSA-N 0.000 abstract 2
- 229940051250 hexylene glycol Drugs 0.000 abstract 1
- 240000004308 marijuana Species 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/658—Medicinal preparations containing organic active ingredients o-phenolic cannabinoids, e.g. cannabidiol, cannabigerolic acid, cannabichromene or tetrahydrocannabinol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
La presente descripción se refiere a la administración transdérmica de cannabidiol (CBD) para la reducción de la frecuencia de las convulsiones en el tratamiento de la "epilepsia resistente al tratamiento" (TRE).
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201962913874P | 2019-10-11 | 2019-10-11 | |
PCT/IB2020/059482 WO2021070120A1 (en) | 2019-10-11 | 2020-10-08 | Transdermal compositions comprising cannabidiol (cbd) for use in the treatment of seizure disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2022004257A true MX2022004257A (es) | 2022-05-26 |
Family
ID=75438036
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2022004257A MX2022004257A (es) | 2019-10-11 | 2020-10-08 | Composicion farmaceutica y metodo para tratamiento de los trastornos convulsionales. |
Country Status (8)
Country | Link |
---|---|
US (1) | US20210113489A1 (es) |
EP (1) | EP4041209A4 (es) |
JP (1) | JP2022551696A (es) |
CN (1) | CN114555067A (es) |
AU (1) | AU2020361741A1 (es) |
CA (1) | CA3155176A1 (es) |
MX (1) | MX2022004257A (es) |
WO (1) | WO2021070120A1 (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN117479930A (zh) * | 2021-04-08 | 2024-01-30 | 长矛治疗股份有限公司 | 用于治疗癫痫发作病症的药物组合物和方法 |
CN113698802B (zh) * | 2021-08-24 | 2022-04-22 | 金隅微观(沧州)化工有限公司 | 一种石墨烯杂化的有机-无机防腐涂料及制备方法 |
CN116459235B (zh) * | 2023-02-21 | 2024-05-24 | 四川旅游学院 | 一种含吡仑帕奈的透皮贴剂及其制备方法 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3962684B2 (ja) * | 2000-11-06 | 2007-08-22 | サムヤン コーポレイション | 改善された水分吸収能および接着性を有する経皮投与剤 |
US8449908B2 (en) * | 2000-12-22 | 2013-05-28 | Alltranz, Llc | Transdermal delivery of cannabidiol |
JP5801794B2 (ja) * | 2009-04-28 | 2015-10-28 | ジネルバ ファーマシューティカルズ, インコーポレイティド | カンナビジオールの製剤及びその使用方法 |
WO2011026144A1 (en) * | 2009-08-31 | 2011-03-03 | Alltranz Inc. | Use of cannabidiol prodrugs in topical and transdermal administration with microneedles |
US9375417B2 (en) * | 2014-12-04 | 2016-06-28 | Mary's Medicinals LLC | Transdermal cannabinoid formulations |
JP2018507262A (ja) * | 2015-03-02 | 2018-03-15 | アフギン ファーマ, エルエルシーAfgin Pharma, Llc | カンナビノイドを用いた、局所局部的神経作用療法 |
US9962340B2 (en) * | 2015-06-09 | 2018-05-08 | Life Tech Global, Llc | Device and method for the transdermal delivery of cannabidiol |
CN108785298A (zh) * | 2017-04-27 | 2018-11-13 | 汉义生物科技(北京)有限公司 | 一种用于治疗癫痫的药物组合物、其制备方法及用途 |
MX2020003004A (es) * | 2017-09-19 | 2020-11-06 | Zynerba Pharmaceuticals Inc | Cannabidiol transdermico sintetico para el tratamiento de epilepsia focal en adultos. |
-
2020
- 2020-10-08 WO PCT/IB2020/059482 patent/WO2021070120A1/en unknown
- 2020-10-08 JP JP2022521633A patent/JP2022551696A/ja active Pending
- 2020-10-08 EP EP20875154.5A patent/EP4041209A4/en active Pending
- 2020-10-08 MX MX2022004257A patent/MX2022004257A/es unknown
- 2020-10-08 US US17/065,851 patent/US20210113489A1/en active Pending
- 2020-10-08 AU AU2020361741A patent/AU2020361741A1/en active Pending
- 2020-10-08 CA CA3155176A patent/CA3155176A1/en active Pending
- 2020-10-08 CN CN202080071113.4A patent/CN114555067A/zh active Pending
Also Published As
Publication number | Publication date |
---|---|
EP4041209A4 (en) | 2024-01-24 |
WO2021070120A1 (en) | 2021-04-15 |
EP4041209A1 (en) | 2022-08-17 |
JP2022551696A (ja) | 2022-12-13 |
US20210113489A1 (en) | 2021-04-22 |
CN114555067A (zh) | 2022-05-27 |
CA3155176A1 (en) | 2021-04-15 |
AU2020361741A1 (en) | 2022-04-07 |
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