MX2021014580A - Derivados heterociclos condensados como moduladores de ensamblaje de la capside. - Google Patents
Derivados heterociclos condensados como moduladores de ensamblaje de la capside.Info
- Publication number
- MX2021014580A MX2021014580A MX2021014580A MX2021014580A MX2021014580A MX 2021014580 A MX2021014580 A MX 2021014580A MX 2021014580 A MX2021014580 A MX 2021014580A MX 2021014580 A MX2021014580 A MX 2021014580A MX 2021014580 A MX2021014580 A MX 2021014580A
- Authority
- MX
- Mexico
- Prior art keywords
- sup
- capsid assembly
- fused heterocycle
- heterocycle derivatives
- assembly modulators
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed systems contains four or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Se dan a conocer compuestos, composiciones y métodos para tratar enfermedades, síndromes, afecciones, y trastornos que se ven afectados por la modulación de CAM1; tales compuestos se representan mediante la Fórmula (I) tal como sigue: (ver Fórmula) donde, R1, R1A, R2, R3, R4, HET, n, X, Y, Z1 y Z2 se definen en el presente documento.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201962853528P | 2019-05-28 | 2019-05-28 | |
PCT/EP2020/064751 WO2020239864A1 (en) | 2019-05-28 | 2020-05-27 | Fused heterocycle derivatives as capsid assembly modulators |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2021014580A true MX2021014580A (es) | 2022-01-11 |
Family
ID=70968930
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2021014580A MX2021014580A (es) | 2019-05-28 | 2020-05-27 | Derivados heterociclos condensados como moduladores de ensamblaje de la capside. |
Country Status (10)
Country | Link |
---|---|
US (1) | US20220153754A1 (es) |
EP (1) | EP3976619A1 (es) |
JP (1) | JP2022535216A (es) |
KR (1) | KR20220015426A (es) |
CN (1) | CN113906031A (es) |
AU (1) | AU2020285314A1 (es) |
BR (1) | BR112021022960A2 (es) |
CA (1) | CA3136519A1 (es) |
MX (1) | MX2021014580A (es) |
WO (1) | WO2020239864A1 (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2024032409A1 (zh) * | 2022-08-09 | 2024-02-15 | 成都百裕制药股份有限公司 | 哌嗪类化合物在联合放疗治疗肿瘤中的用途 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MX2017008720A (es) * | 2014-12-30 | 2018-01-25 | Novira Therapeutics Inc | Derivados y metodos para tratamiento de las infecciones por hepatitis b. |
CN114057739A (zh) * | 2016-06-29 | 2022-02-18 | 诺维拉治疗公司 | 二氮杂酮衍生物及其在治疗乙型肝炎感染中的用途 |
JP6935434B2 (ja) | 2016-06-29 | 2021-09-15 | ノヴィラ・セラピューティクス・インコーポレイテッド | オキサジアゼピノン誘導体及びb型肝炎感染症の治療におけるその使用 |
-
2020
- 2020-05-27 MX MX2021014580A patent/MX2021014580A/es unknown
- 2020-05-27 CN CN202080040337.9A patent/CN113906031A/zh active Pending
- 2020-05-27 AU AU2020285314A patent/AU2020285314A1/en not_active Abandoned
- 2020-05-27 WO PCT/EP2020/064751 patent/WO2020239864A1/en unknown
- 2020-05-27 BR BR112021022960A patent/BR112021022960A2/pt not_active Application Discontinuation
- 2020-05-27 EP EP20729989.2A patent/EP3976619A1/en not_active Withdrawn
- 2020-05-27 KR KR1020217042206A patent/KR20220015426A/ko unknown
- 2020-05-27 US US17/595,819 patent/US20220153754A1/en active Pending
- 2020-05-27 JP JP2021570398A patent/JP2022535216A/ja active Pending
- 2020-05-27 CA CA3136519A patent/CA3136519A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
AU2020285314A1 (en) | 2021-11-25 |
US20220153754A1 (en) | 2022-05-19 |
JP2022535216A (ja) | 2022-08-05 |
WO2020239864A1 (en) | 2020-12-03 |
CA3136519A1 (en) | 2020-12-03 |
KR20220015426A (ko) | 2022-02-08 |
EP3976619A1 (en) | 2022-04-06 |
CN113906031A (zh) | 2022-01-07 |
BR112021022960A2 (pt) | 2022-01-04 |
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