MX2021008717A - Metodos de tratamiento contra adicciones. - Google Patents
Metodos de tratamiento contra adicciones.Info
- Publication number
- MX2021008717A MX2021008717A MX2021008717A MX2021008717A MX2021008717A MX 2021008717 A MX2021008717 A MX 2021008717A MX 2021008717 A MX2021008717 A MX 2021008717A MX 2021008717 A MX2021008717 A MX 2021008717A MX 2021008717 A MX2021008717 A MX 2021008717A
- Authority
- MX
- Mexico
- Prior art keywords
- methods
- treating addiction
- carbolines
- prevention
- pharmaceutically acceptable
- Prior art date
Links
- 206010012335 Dependence Diseases 0.000 title 1
- 208000026251 Opioid-Related disease Diseases 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 201000005040 opiate dependence Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Addiction (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La invención se refiere a particulares gamma-carbolinas fusionadas con heterociclo sustituido, en forma de sal libre, sólida y farmacéuticamente aceptable y/o sustancialmente pura, tal como se describe en la presente, a composiciones farmacéuticas de las mismas para su uso en métodos para el tratamiento o prevención de recaídas por adicción a opiáceos.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962795899P | 2019-01-23 | 2019-01-23 | |
| PCT/US2020/014818 WO2020154519A2 (en) | 2019-01-23 | 2020-01-23 | Methods of treating addiction |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2021008717A true MX2021008717A (es) | 2021-10-26 |
Family
ID=71735540
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2021008717A MX2021008717A (es) | 2019-01-23 | 2020-01-23 | Metodos de tratamiento contra adicciones. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20220088014A1 (es) |
| EP (1) | EP3914235A4 (es) |
| JP (1) | JP7555343B2 (es) |
| KR (1) | KR20210118889A (es) |
| CN (2) | CN113329742A (es) |
| AU (1) | AU2020212019A1 (es) |
| CA (1) | CA3125777A1 (es) |
| IL (1) | IL284797A (es) |
| MX (1) | MX2021008717A (es) |
| WO (1) | WO2020154519A2 (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116210637A (zh) * | 2021-12-06 | 2023-06-06 | 中国科学院深圳先进技术研究院 | 一种成瘾药物戒断后复吸相关调控基因及其筛选方法 |
| WO2024145659A1 (en) * | 2022-12-30 | 2024-07-04 | Intra-Cellular Therapies, Inc. | Heterocycle fused gamma-carbolines acting on the serotonine 5-ht2a receptor |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE277048T1 (de) * | 1999-06-15 | 2004-10-15 | Bristol Myers Squibb Pharma Co | Substituierte hetercyclisch kondensierte gamma carboline |
| PL3407888T3 (pl) * | 2016-01-26 | 2021-08-30 | Intra-Cellular Therapies, Inc. | Związki pirydopirolochinoksaliny, ich kompozycje i zastosowania |
| US10906906B2 (en) * | 2016-12-29 | 2021-02-02 | Intra-Cellular Therapies, Inc. | Organic compounds |
| US10961245B2 (en) * | 2016-12-29 | 2021-03-30 | Intra-Cellular Therapies, Inc. | Substituted heterocycle fused gamma-carbolines for treatment of central nervous system disorders |
| CN111093664B (zh) * | 2017-07-26 | 2023-06-02 | 细胞内治疗公司 | 有机化合物 |
| WO2019023062A1 (en) * | 2017-07-26 | 2019-01-31 | Intra-Cellular Therapies, Inc. | ORGANIC COMPOUNDS |
| US20220048910A1 (en) * | 2018-12-21 | 2022-02-17 | Intra-Cellular Therapies, Inc. | Organic compounds |
-
2020
- 2020-01-23 WO PCT/US2020/014818 patent/WO2020154519A2/en unknown
- 2020-01-23 CN CN202080010604.8A patent/CN113329742A/zh active Pending
- 2020-01-23 US US17/425,641 patent/US20220088014A1/en active Pending
- 2020-01-23 CA CA3125777A patent/CA3125777A1/en active Pending
- 2020-01-23 JP JP2021542362A patent/JP7555343B2/ja active Active
- 2020-01-23 KR KR1020217026674A patent/KR20210118889A/ko unknown
- 2020-01-23 EP EP20745504.9A patent/EP3914235A4/en active Pending
- 2020-01-23 MX MX2021008717A patent/MX2021008717A/es unknown
- 2020-01-23 AU AU2020212019A patent/AU2020212019A1/en active Pending
- 2020-01-23 CN CN202311661516.6A patent/CN118105390A/zh active Pending
-
2021
- 2021-07-12 IL IL284797A patent/IL284797A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20220088014A1 (en) | 2022-03-24 |
| CA3125777A1 (en) | 2020-07-30 |
| JP2022518495A (ja) | 2022-03-15 |
| AU2020212019A1 (en) | 2021-09-16 |
| CN118105390A (zh) | 2024-05-31 |
| JP7555343B2 (ja) | 2024-09-24 |
| EP3914235A2 (en) | 2021-12-01 |
| KR20210118889A (ko) | 2021-10-01 |
| IL284797A (en) | 2021-08-31 |
| WO2020154519A3 (en) | 2020-09-17 |
| CN113329742A (zh) | 2021-08-31 |
| EP3914235A4 (en) | 2022-09-07 |
| WO2020154519A2 (en) | 2020-07-30 |
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