MX2021006503A - Métodos para la expansión in vivo selectiva de poblaciones de células t gamma delta y composiciones de estas. - Google Patents

Métodos para la expansión in vivo selectiva de poblaciones de células t gamma delta y composiciones de estas.

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Publication number
MX2021006503A
MX2021006503A MX2021006503A MX2021006503A MX2021006503A MX 2021006503 A MX2021006503 A MX 2021006503A MX 2021006503 A MX2021006503 A MX 2021006503A MX 2021006503 A MX2021006503 A MX 2021006503A MX 2021006503 A MX2021006503 A MX 2021006503A
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Mexico
Prior art keywords
methods
compositions
selective
cell populations
vivo expansion
Prior art date
Application number
MX2021006503A
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English (en)
Inventor
Orit Foord
Hui Shao
Aya Jakobovits
Yifeng Frank Jing
Daulet Satpayev
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Adicet Bio Inc
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Publication date
Application filed by Adicet Bio Inc filed Critical Adicet Bio Inc
Publication of MX2021006503A publication Critical patent/MX2021006503A/es

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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/663Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
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    • A61K39/4611T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
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    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0636T lymphocytes

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
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  • Animal Behavior & Ethology (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
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  • General Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La presente invención se refiere a métodos para la activación, expansión y/o mantenimiento in vivo selectiva de la o las poblaciones de células T ?d, composiciones y mezclas de estas y métodos para su uso como una terapia. Los métodos y composiciones de la descripción son útiles en el tratamiento de diversos cánceres, enfermedades infecciosas y trastornos autoinmunes.
MX2021006503A 2018-12-03 2019-12-03 Métodos para la expansión in vivo selectiva de poblaciones de células t gamma delta y composiciones de estas. MX2021006503A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862774817P 2018-12-03 2018-12-03
PCT/US2019/064319 WO2020117862A1 (en) 2018-12-03 2019-12-03 Methods for selective in vivo expansion of gamma delta t-cell populations and compositions thereof

Publications (1)

Publication Number Publication Date
MX2021006503A true MX2021006503A (es) 2021-08-05

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Family Applications (1)

Application Number Title Priority Date Filing Date
MX2021006503A MX2021006503A (es) 2018-12-03 2019-12-03 Métodos para la expansión in vivo selectiva de poblaciones de células t gamma delta y composiciones de estas.

Country Status (12)

Country Link
US (1) US20220218747A1 (es)
EP (1) EP3890757A1 (es)
JP (1) JP2022510387A (es)
KR (1) KR20210099615A (es)
CN (1) CN113518624A (es)
AU (1) AU2019394877A1 (es)
BR (1) BR112021010804A2 (es)
CA (1) CA3126896A1 (es)
IL (1) IL283614A (es)
MX (1) MX2021006503A (es)
SG (1) SG11202105860QA (es)
WO (1) WO2020117862A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2022006547A (es) * 2019-12-03 2022-08-19 Adicet Bio Inc Métodos para la expansión de poblaciones de células t gamma delta con agentes multivalentes y composiciones de estas.
WO2022109477A1 (en) * 2020-11-23 2022-05-27 University Of Florida Research Foundation, Incorporated Use of insulin-like growth factors with gamma-chain cytokines to induce homeostatic proliferation of lymphocytes

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US4657760A (en) 1979-03-20 1987-04-14 Ortho Pharmaceutical Corporation Methods and compositions using monoclonal antibody to human T cells
US5206344A (en) 1985-06-26 1993-04-27 Cetus Oncology Corporation Interleukin-2 muteins and polymer conjugation thereof
US5225212A (en) 1989-10-20 1993-07-06 Liposome Technology, Inc. Microreservoir liposome composition and method
US6075181A (en) 1990-01-12 2000-06-13 Abgenix, Inc. Human antibodies derived from immunized xenomice
US6150584A (en) 1990-01-12 2000-11-21 Abgenix, Inc. Human antibodies derived from immunized xenomice
EP0633943A4 (en) 1992-04-03 1997-05-02 Alexander T Young GENTHERAPY USING TARGETED VIRAL VECTORS.
AU2003251286B2 (en) 2002-01-23 2007-08-16 The University Of Utah Research Foundation Targeted chromosomal mutagenesis using zinc finger nucleases
US7985739B2 (en) 2003-06-04 2011-07-26 The Board Of Trustees Of The Leland Stanford Junior University Enhanced sleeping beauty transposon system and methods for using the same
MX336846B (es) 2010-01-22 2016-02-03 Sangamo Biosciences Inc Alteracion genomica dirigida.
MY160662A (en) 2011-04-01 2017-03-15 Memorial Sloan Kettering Cancer Center T cell receptor-like antibodies specific for a wt1 peptide presented by hla-a2
EP2684600A1 (en) 2012-07-10 2014-01-15 Laboratoires Meiners Sarl Core-shell capsules and methods for encapsulation of reactive ingredients by diffusional exchange through spherical capsule membranes
WO2014072446A1 (en) * 2012-11-08 2014-05-15 INSERM (Institut National de la Santé et de la Recherche Médicale) Method for inducing il-2-free proliferation of gamma delta t cells
WO2014134412A1 (en) 2013-03-01 2014-09-04 Regents Of The University Of Minnesota Talen-based gene correction
CN104651308A (zh) * 2013-11-22 2015-05-27 深圳先进技术研究院 一种用磷酸盐扩增γδT细胞的方法及其应用
RU2756247C2 (ru) 2014-11-17 2021-09-28 Эдисет Био, Инк. Генетически модифицированные гамма дельта т-клетки
MA42895A (fr) 2015-07-15 2018-05-23 Juno Therapeutics Inc Cellules modifiées pour thérapie cellulaire adoptive
WO2017197347A1 (en) * 2016-05-12 2017-11-16 Adicet Bio, Inc. METHODS FOR SELECTIVE EXPANSION OF γδ T-CELL POPULATIONS AND COMPOSITIONS THEREOF
SG11202004506WA (en) 2017-11-15 2020-06-29 Adicet Bio Inc METHODS FOR SELECTIVE EXPANSION OF d3 ?d T-CELL POPULATIONS AND COMPOSITIONS THEREOF

Also Published As

Publication number Publication date
US20220218747A1 (en) 2022-07-14
WO2020117862A1 (en) 2020-06-11
IL283614A (en) 2021-07-29
CA3126896A1 (en) 2020-06-11
EP3890757A1 (en) 2021-10-13
JP2022510387A (ja) 2022-01-26
KR20210099615A (ko) 2021-08-12
BR112021010804A2 (pt) 2021-11-16
AU2019394877A1 (en) 2021-06-17
CN113518624A (zh) 2021-10-19
SG11202105860QA (en) 2021-07-29

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