MX2021004336A - Crystalline methylthionium chloride (methylene blue) hydrates. - Google Patents
Crystalline methylthionium chloride (methylene blue) hydrates.Info
- Publication number
- MX2021004336A MX2021004336A MX2021004336A MX2021004336A MX2021004336A MX 2021004336 A MX2021004336 A MX 2021004336A MX 2021004336 A MX2021004336 A MX 2021004336A MX 2021004336 A MX2021004336 A MX 2021004336A MX 2021004336 A MX2021004336 A MX 2021004336A
- Authority
- MX
- Mexico
- Prior art keywords
- hydrates
- methylene blue
- crystalline
- chloride
- methylthionium chloride
- Prior art date
Links
- 229960000907 methylthioninium chloride Drugs 0.000 title abstract 3
- 150000004677 hydrates Chemical class 0.000 title abstract 2
- CXKWCBBOMKCUKX-UHFFFAOYSA-M methylene blue Chemical compound [Cl-].C1=CC(N(C)C)=CC2=[S+]C3=CC(N(C)C)=CC=C3N=C21 CXKWCBBOMKCUKX-UHFFFAOYSA-M 0.000 title 2
- XQAXGZLFSSPBMK-UHFFFAOYSA-M [7-(dimethylamino)phenothiazin-3-ylidene]-dimethylazanium;chloride;trihydrate Chemical compound O.O.O.[Cl-].C1=CC(=[N+](C)C)C=C2SC3=CC(N(C)C)=CC=C3N=C21 XQAXGZLFSSPBMK-UHFFFAOYSA-M 0.000 abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 150000004683 dihydrates Chemical group 0.000 abstract 1
- 150000004682 monohydrates Chemical group 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Abstract
Three dihydrate forms B, C and D and a monohydrate form E of methylthloninium chloride (methylene blue) are described. Forms B, C, D and E can be prepared under controlled humidity and temperature from methylthioninium chloride with higher water content or conversion of a hydrate. The hydrates can be incorporated in pharmaceutical compositions.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MX2021004336A MX2021004336A (en) | 2021-04-15 | 2021-04-15 | Crystalline methylthionium chloride (methylene blue) hydrates. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MX2021004336A MX2021004336A (en) | 2021-04-15 | 2021-04-15 | Crystalline methylthionium chloride (methylene blue) hydrates. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2021004336A true MX2021004336A (en) | 2022-10-17 |
Family
ID=88696229
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2021004336A MX2021004336A (en) | 2021-04-15 | 2021-04-15 | Crystalline methylthionium chloride (methylene blue) hydrates. |
Country Status (1)
| Country | Link |
|---|---|
| MX (1) | MX2021004336A (en) |
-
2021
- 2021-04-15 MX MX2021004336A patent/MX2021004336A/en unknown
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