MX2021002277A - Composicion farmaceutica que comprende agente antiplaquetario e inhibidor de la secrecion de acido gastrico. - Google Patents

Composicion farmaceutica que comprende agente antiplaquetario e inhibidor de la secrecion de acido gastrico.

Info

Publication number
MX2021002277A
MX2021002277A MX2021002277A MX2021002277A MX2021002277A MX 2021002277 A MX2021002277 A MX 2021002277A MX 2021002277 A MX2021002277 A MX 2021002277A MX 2021002277 A MX2021002277 A MX 2021002277A MX 2021002277 A MX2021002277 A MX 2021002277A
Authority
MX
Mexico
Prior art keywords
pharmaceutical composition
gastric acid
acid secretion
antiplatelet agent
secretion inhibitor
Prior art date
Application number
MX2021002277A
Other languages
English (en)
Inventor
Tae Keun Cho
Young Dae Cho
Eunji Kwon
Myung Jin Shin
Original Assignee
Hk Inno N Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hk Inno N Corp filed Critical Hk Inno N Corp
Publication of MX2021002277A publication Critical patent/MX2021002277A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La presente invención proporciona una composición farmacéutica que comprende clopidogrel o sus sales farmacéuticamente aceptables; y un compuesto de Fórmula 1 o sus sales farmacéuticamente aceptables como un ingrediente activo: Fórmula 1 (ver Fórmula) La composición farmacéutica de la presente invención tiene una ventaja de mantenimiento de un efecto medicinal de clopidogrel mientras que se evita o trata un efecto colateral del clopidogrel, es decir, trastornos gastrointestinales.
MX2021002277A 2018-08-28 2019-08-27 Composicion farmaceutica que comprende agente antiplaquetario e inhibidor de la secrecion de acido gastrico. MX2021002277A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020180101047A KR20200024413A (ko) 2018-08-28 2018-08-28 항혈소판제와 산 분비 억제제를 포함하는 약학 조성물
PCT/KR2019/010891 WO2020045940A1 (en) 2018-08-28 2019-08-27 Pharmaceutical composition comprising antiplatelet agent and gastric acid secretion inhibitor

Publications (1)

Publication Number Publication Date
MX2021002277A true MX2021002277A (es) 2021-08-11

Family

ID=69644592

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2021002277A MX2021002277A (es) 2018-08-28 2019-08-27 Composicion farmaceutica que comprende agente antiplaquetario e inhibidor de la secrecion de acido gastrico.

Country Status (16)

Country Link
JP (1) JP7150976B2 (es)
KR (1) KR20200024413A (es)
CN (1) CN112601523A (es)
AR (1) AR116021A1 (es)
AU (1) AU2019327262B2 (es)
BR (1) BR112021003563A2 (es)
CA (1) CA3107426C (es)
EA (1) EA202190621A1 (es)
GE (1) GEP20227388B (es)
JO (1) JOP20190198A1 (es)
MX (1) MX2021002277A (es)
PH (1) PH12021550389A1 (es)
SA (1) SA521421331B1 (es)
UA (1) UA127608C2 (es)
UY (1) UY38345A (es)
WO (1) WO2020045940A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20190043437A (ko) 2017-10-18 2019-04-26 씨제이헬스케어 주식회사 단백질 키나제 억제제로서의 헤테로고리 화합물
UY39094A (es) * 2020-02-27 2021-07-30 Hk Inno N Corp Composición farmacéutica que comprende compuesto derivado de bencimidazol
MX2023004611A (es) * 2020-10-23 2023-05-08 Hk Inno N Corp Comprimido de desintegracion oral que comprende un compuesto derivado de benzimidazol y procedimiento de preparacion del mismo.
KR20230127317A (ko) * 2020-12-30 2023-08-31 에이치케이이노엔 주식회사 테고프라잔과 비스테로이드성 항염증 약물을 포함하는약학적 조성물

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003270861A1 (en) * 2002-10-02 2004-04-23 Bristol-Myers Squibb Company Novel combination of a factor xa inhibitor and clopidogrel
US20060177504A1 (en) 2005-02-08 2006-08-10 Renjit Sundharadas Combination pain medication
CA2631880C (en) 2005-12-19 2011-03-29 Pfizer Inc. Chromane substituted benzimidazoles and their use as acid pump inhibitors
EP2007362B1 (en) 2006-04-04 2018-09-05 KG Acquisition LLC Oral dosage forms including an antiplatelet agent and an acid inhibitor
WO2010009745A1 (en) 2008-07-25 2010-01-28 Pharmathen S.A. Solid oral dosage form containing anti-platelet agent clopidogrel and method for the preparation thereof
CA2848764A1 (en) 2011-09-14 2013-03-21 Pozen Inc. Controlled dosing of clopidogrel with gastric acid inhibition therapies
US20140271816A1 (en) 2013-03-15 2014-09-18 Frederick Timothy Guilford Treatment of potential platelet aggregation with liposomally formulated glutathione and clopidogrel
KR101829706B1 (ko) 2016-09-21 2018-02-19 씨제이헬스케어 주식회사 벤즈이미다졸 유도체의 산부가염
KR101829705B1 (ko) 2016-09-21 2018-02-19 씨제이헬스케어 주식회사 안정성이 향상된 주사용 조성물

Also Published As

Publication number Publication date
CN112601523A (zh) 2021-04-02
UA127608C2 (uk) 2023-11-01
AU2019327262A1 (en) 2021-04-29
KR20200024413A (ko) 2020-03-09
AU2019327262B2 (en) 2023-02-09
CA3107426A1 (en) 2020-03-05
CA3107426C (en) 2023-08-01
EA202190621A1 (ru) 2021-06-03
BR112021003563A2 (pt) 2021-05-18
EP3843722A1 (en) 2021-07-07
EP3843722A4 (en) 2022-05-11
AR116021A1 (es) 2021-03-25
UY38345A (es) 2020-03-31
JOP20190198A1 (ar) 2020-02-28
GEP20227388B (en) 2022-06-10
JP7150976B2 (ja) 2022-10-11
PH12021550389A1 (en) 2021-09-20
SA521421331B1 (ar) 2023-11-19
WO2020045940A1 (en) 2020-03-05
US20210251967A1 (en) 2021-08-19
JP2022501320A (ja) 2022-01-06

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