MX2020013302A - Métodos y composiciones para prevenir o tratar calcificación de tejido. - Google Patents

Métodos y composiciones para prevenir o tratar calcificación de tejido.

Info

Publication number
MX2020013302A
MX2020013302A MX2020013302A MX2020013302A MX2020013302A MX 2020013302 A MX2020013302 A MX 2020013302A MX 2020013302 A MX2020013302 A MX 2020013302A MX 2020013302 A MX2020013302 A MX 2020013302A MX 2020013302 A MX2020013302 A MX 2020013302A
Authority
MX
Mexico
Prior art keywords
compositions
prevent
methods
tissue calcification
progression
Prior art date
Application number
MX2020013302A
Other languages
English (en)
Spanish (es)
Inventor
James A Tumlin
Paul L Darke
John M Rudey
Original Assignee
Epizon Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Epizon Pharma Inc filed Critical Epizon Pharma Inc
Publication of MX2020013302A publication Critical patent/MX2020013302A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • A61K31/122Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • A61K31/366Lactones having six-membered rings, e.g. delta-lactones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • A61K31/405Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00Preparations for use in therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
MX2020013302A 2018-06-08 2019-06-07 Métodos y composiciones para prevenir o tratar calcificación de tejido. MX2020013302A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862682796P 2018-06-08 2018-06-08
PCT/US2019/036138 WO2019237053A1 (en) 2018-06-08 2019-06-07 Methods and compositions for preventing or treating tissue calcification

Publications (1)

Publication Number Publication Date
MX2020013302A true MX2020013302A (es) 2021-05-12

Family

ID=68765387

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2020013302A MX2020013302A (es) 2018-06-08 2019-06-07 Métodos y composiciones para prevenir o tratar calcificación de tejido.
MX2024013515A MX2024013515A (es) 2018-06-08 2020-12-07 Metodos y composiciones para prevenir o tratar calcificacion de tejido

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2024013515A MX2024013515A (es) 2018-06-08 2020-12-07 Metodos y composiciones para prevenir o tratar calcificacion de tejido

Country Status (11)

Country Link
US (8) US10688064B2 (enExample)
EP (1) EP3801477A4 (enExample)
JP (2) JP2021527128A (enExample)
KR (1) KR20210018423A (enExample)
CN (1) CN113038940A (enExample)
AU (1) AU2019282420B2 (enExample)
CA (1) CA3102977A1 (enExample)
IL (1) IL279245B2 (enExample)
MX (2) MX2020013302A (enExample)
SG (1) SG11202012070YA (enExample)
WO (1) WO2019237053A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019237054A1 (en) 2018-06-08 2019-12-12 Epizon Pharma, Inc. Methods and compositions for preventing or treating calciphylaxis
IL279245B2 (en) 2018-06-08 2024-03-01 Epizon Pharma Inc Compositions comprising menaquinone-7 (mk-7) and/or menquinol for prophylaxis of tissue calcification
WO2020055678A1 (en) 2018-09-12 2020-03-19 Epizon Pharma, Inc. Menaquinol compositions and methods of treatment
MX2021010977A (es) * 2019-03-12 2021-12-10 Nattopharma As Uso de vitamina k en combinacion con anticoagulantes.
KR20240045216A (ko) * 2021-07-05 2024-04-05 위니베르시테이트 마스트리흐트 칼슘 결정 침착 질환의 치료 수단 및 방법
WO2023129413A1 (en) * 2021-12-31 2023-07-06 Ingredient Fusion, Llc Molecular complexing method, formulation and manufacturing for enhanced nutrient delivery
WO2024071848A1 (ko) * 2022-09-27 2024-04-04 경북대학교 산학협력단 혈관석회화 치료제 스크리닝 방법
WO2025075468A1 (ko) * 2023-10-06 2025-04-10 주식회사 레드엔비아 혈관 또는 판막 협착증의 예방 또는 치료용 병용제제

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050176778A1 (en) 2001-08-03 2005-08-11 Vitak Bv Isoprenyl derivatives and their use in the title treatment and prevention of osteoporosis and cardiovascular calcification
WO2005030190A1 (en) * 2003-09-26 2005-04-07 Natural Asa Natural menaquinone 7 compositions
SI1728507T1 (sl) 2005-06-03 2011-07-29 Nattopharma Asa Uporaba vitamina K za reverziranje kalcifikacije krvnih Ĺľil
EP2046312B1 (en) * 2006-07-14 2020-02-19 Kaydence Pharma AS Pharmaceutical and nutraceutical products comprising vitamin k2
GB0817528D0 (en) 2008-09-24 2008-10-29 Syntavit As Process
WO2012059942A2 (en) 2010-11-01 2012-05-10 Viridis Biopharma Pvt. Ltd Dynamic balancing of autonomic nervous system through vitamin mk-7
GB201203705D0 (en) 2012-03-02 2012-04-18 Kappa Bioscience As Prodrugs
ES2869202T3 (es) 2012-06-18 2021-10-25 Fresenius Kabi Deutschland Gmbh Sistema de cánula para vía para la punción de vías centrales de acceso subcutáneo
WO2014191466A1 (en) 2013-05-28 2014-12-04 Nattopharma Asa Menaquinone supplementation and vascular health
GB201314245D0 (en) 2013-08-08 2013-09-25 Kappa Bioscience As Provitamins
WO2016131993A2 (en) * 2015-02-20 2016-08-25 Vitak B.V. Vitamin k and capillary function
MX2017011934A (es) 2015-03-20 2018-02-09 Gnosis Spa Formas solidas de menaquinoles.
IT201700085412A1 (it) 2017-07-26 2019-01-26 Pharmanutra S P A Composizione per uso nella prevenzione e nel trattamento di patologie dell'apparato cardiovascolare
US10368858B1 (en) 2018-01-25 2019-08-06 Ring Orthopedics, Inc. Suture passer
WO2019237054A1 (en) 2018-06-08 2019-12-12 Epizon Pharma, Inc. Methods and compositions for preventing or treating calciphylaxis
IL279245B2 (en) 2018-06-08 2024-03-01 Epizon Pharma Inc Compositions comprising menaquinone-7 (mk-7) and/or menquinol for prophylaxis of tissue calcification

Also Published As

Publication number Publication date
US20240009144A1 (en) 2024-01-11
AU2019282420B2 (en) 2025-03-20
IL279245B1 (en) 2023-11-01
AU2019282420A1 (en) 2021-01-07
US20200206159A1 (en) 2020-07-02
US20210093584A1 (en) 2021-04-01
MX2024013515A (es) 2024-12-06
US11723882B2 (en) 2023-08-15
US20250302772A1 (en) 2025-10-02
WO2019237053A1 (en) 2019-12-12
IL279245B2 (en) 2024-03-01
CN113038940A (zh) 2021-06-25
US20210378986A1 (en) 2021-12-09
US11033515B2 (en) 2021-06-15
US20190374484A1 (en) 2019-12-12
JP2021527128A (ja) 2021-10-11
US12377060B2 (en) 2025-08-05
US20200222337A1 (en) 2020-07-16
JP2024073612A (ja) 2024-05-29
EP3801477A1 (en) 2021-04-14
IL279245A (en) 2021-01-31
US10744101B2 (en) 2020-08-18
EP3801477A4 (en) 2022-02-23
JP7847880B2 (ja) 2026-04-20
SG11202012070YA (en) 2021-01-28
KR20210018423A (ko) 2021-02-17
US10874623B2 (en) 2020-12-29
CA3102977A1 (en) 2019-12-12
US10744102B2 (en) 2020-08-18
US20200206158A1 (en) 2020-07-02
US10688064B2 (en) 2020-06-23

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