MX2020012652A - Oligonucleotido bicatenario especifico del gen de anfirregulina y composicion para prevenir y tratar enfermedades relacionadas con la fibrosis y enfermedades respiratorias, que comprende el mismo. - Google Patents

Oligonucleotido bicatenario especifico del gen de anfirregulina y composicion para prevenir y tratar enfermedades relacionadas con la fibrosis y enfermedades respiratorias, que comprende el mismo.

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Publication number
MX2020012652A
MX2020012652A MX2020012652A MX2020012652A MX2020012652A MX 2020012652 A MX2020012652 A MX 2020012652A MX 2020012652 A MX2020012652 A MX 2020012652A MX 2020012652 A MX2020012652 A MX 2020012652A MX 2020012652 A MX2020012652 A MX 2020012652A
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Mexico
Prior art keywords
stranded oligonucleotide
double
preventing
composition
same
Prior art date
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MX2020012652A
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English (en)
Inventor
Tae- Rim KIM
Pyoung Oh Yoon
Youngho Ko
Seon Joo Bae
Han- Oh PARK
Seung Seob Son
Sung Il Yun
Jun-Hong Park
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Bioneer Corp
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Publication of MX2020012652A publication Critical patent/MX2020012652A/es

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    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
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    • A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1136—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against growth factors, growth regulators, cytokines, lymphokines or hormones
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    • A—HUMAN NECESSITIES
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    • A61K9/00—Medicinal preparations characterised by special physical form
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C12N2320/10—Applications; Uses in screening processes
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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Abstract

La presente invención se refiere a un oligonucleótido bicatenario el cual puede inhibir de forma muy específica y eficazmente una expresión de anfirreguiina y, preferentemente, un oligonucleótido bicatenario que comprende una secuencia en la forma de ARNIARN, ADN/ADN, o un híbrido de ADN/ARN, una estructura de oligonucleótido bicatenario que comprende el oligonucleótido bicatenario, nanopartículas que comprende la estructura de oligonucleótido bicatenario, y un uso preventivo o terapéutico de enfermedades fibrosas o respiratorias del mismo.
MX2020012652A 2018-05-25 2019-05-22 Oligonucleotido bicatenario especifico del gen de anfirregulina y composicion para prevenir y tratar enfermedades relacionadas con la fibrosis y enfermedades respiratorias, que comprende el mismo. MX2020012652A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20180059783 2018-05-25
PCT/KR2019/006144 WO2019225968A1 (ko) 2018-05-25 2019-05-22 엠피레귤린 유전자 특이적 이중가닥 올리고뉴클레오티드 및 이를 포함하는 섬유증 관련 질환 및 호흡기 관련 질환 예방 및 치료용 조성물

Publications (1)

Publication Number Publication Date
MX2020012652A true MX2020012652A (es) 2021-05-27

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MX2020012652A MX2020012652A (es) 2018-05-25 2019-05-22 Oligonucleotido bicatenario especifico del gen de anfirregulina y composicion para prevenir y tratar enfermedades relacionadas con la fibrosis y enfermedades respiratorias, que comprende el mismo.

Country Status (12)

Country Link
US (3) US20210189398A1 (es)
EP (1) EP3816285A4 (es)
JP (2) JP7154403B2 (es)
KR (1) KR20190134506A (es)
CN (1) CN112368382A (es)
AU (2) AU2019272190B2 (es)
BR (1) BR112020023968A2 (es)
CA (1) CA3101320A1 (es)
MX (1) MX2020012652A (es)
SA (1) SA520420620B1 (es)
WO (1) WO2019225968A1 (es)
ZA (1) ZA202008040B (es)

Families Citing this family (5)

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CA3101320A1 (en) 2018-05-25 2019-11-28 Bioneer Corporation Amphiregulin gene-specific double-stranded oligonucleotide and composition for preventing and treating fibrosis-related diseases and respiratory diseases, comprising same
BR112022020190A2 (pt) * 2020-04-10 2022-11-22 Bioneer Corp Composição usando amostra de urina para diagnóstico de doença renal
WO2021229479A1 (ko) * 2020-05-14 2021-11-18 (주)바이오니아 엠피레귤린 특이적 이중가닥 올리고뉴클레오티드 구조체를 포함하는 비만 관련 질환의 예방 및 치료용 조성물
WO2021234647A1 (ko) * 2020-05-22 2021-11-25 (주)바이오니아 이중가닥 올리고뉴클레오티드 및 이를 포함하는 코로나바이러스감염증-19(covid-19) 치료용 조성물
WO2022191567A1 (ko) * 2021-03-08 2022-09-15 (주)바이오니아 Covid-19를 포함하는 호흡기 바이러스 감염증, 바이러스 감염에 의한 폐섬유증, 또는 호흡기 질환 예방 또는 치료를 위한 초음파 방식 연무식 흡입기를 이용한 이중가닥 올리고뉴클레오티드 구조체 투여용 조성물

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Also Published As

Publication number Publication date
US20230203494A1 (en) 2023-06-29
ZA202008040B (en) 2023-02-22
JP2021525103A (ja) 2021-09-24
US20210189398A1 (en) 2021-06-24
CA3101320A1 (en) 2019-11-28
AU2019272190B2 (en) 2022-12-01
WO2019225968A1 (ko) 2019-11-28
BR112020023968A2 (pt) 2021-02-23
AU2023201262A1 (en) 2023-04-27
EP3816285A4 (en) 2022-03-16
KR20190134506A (ko) 2019-12-04
US12037589B2 (en) 2024-07-16
EP3816285A1 (en) 2021-05-05
SA520420620B1 (ar) 2024-03-17
US20230332154A1 (en) 2023-10-19
AU2019272190A1 (en) 2020-12-17
JP2023002587A (ja) 2023-01-10
JP7154403B2 (ja) 2022-10-17
CN112368382A (zh) 2021-02-12

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