MX2020012627A - Metodo para la produccion de compuestos monoterpenoides. - Google Patents

Metodo para la produccion de compuestos monoterpenoides.

Info

Publication number
MX2020012627A
MX2020012627A MX2020012627A MX2020012627A MX2020012627A MX 2020012627 A MX2020012627 A MX 2020012627A MX 2020012627 A MX2020012627 A MX 2020012627A MX 2020012627 A MX2020012627 A MX 2020012627A MX 2020012627 A MX2020012627 A MX 2020012627A
Authority
MX
Mexico
Prior art keywords
monoterpenoid
producing
monoterpenoid compounds
compound
providing
Prior art date
Application number
MX2020012627A
Other languages
English (en)
Inventor
Sarah O''CONNOR
Benjamin Robert Lichman
Original Assignee
Innes John Centre
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Innes John Centre filed Critical Innes John Centre
Publication of MX2020012627A publication Critical patent/MX2020012627A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02Oxygen as only ring hetero atoms
    • C12P17/06Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P5/00Preparation of hydrocarbons or halogenated hydrocarbons
    • C12P5/007Preparation of hydrocarbons or halogenated hydrocarbons containing one or more isoprene units, i.e. terpenes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/94Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0006Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/001Oxidoreductases (1.) acting on the CH-CH group of donors (1.3)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90Isomerases (5.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y101/00Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y103/00Oxidoreductases acting on the CH-CH group of donors (1.3)
    • C12Y103/01Oxidoreductases acting on the CH-CH group of donors (1.3) with NAD+ or NADP+ as acceptor (1.3.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y505/00Intramolecular lyases (5.5)
    • C12Y505/01Intramolecular lyases (5.5.1)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Nutrition Science (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)

Abstract

La invención se refiere a enzimas y métodos para producir un compuesto monoterpenoide. En un aspecto, la invención es un método para producir un compuesto monoterpenoide, que comprende los pasos de (1) proporcionar un precursor monoterpenoide; (2) proporcionar una enzima NEPS; y (3) poner en contacto el precursor monoterpenoide con la enzima en condiciones catalíticas para producir un compuesto monoterpenoide.
MX2020012627A 2018-05-25 2019-05-22 Metodo para la produccion de compuestos monoterpenoides. MX2020012627A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1808663.7A GB201808663D0 (en) 2018-05-25 2018-05-25 Method
PCT/GB2019/051409 WO2019224536A1 (en) 2018-05-25 2019-05-22 Method for producing monoterpenoid compounds

Publications (1)

Publication Number Publication Date
MX2020012627A true MX2020012627A (es) 2021-04-28

Family

ID=62812358

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2020012627A MX2020012627A (es) 2018-05-25 2019-05-22 Metodo para la produccion de compuestos monoterpenoides.

Country Status (10)

Country Link
US (1) US20210207183A1 (es)
EP (1) EP3802837A1 (es)
JP (1) JP2021525098A (es)
KR (1) KR20210015897A (es)
CN (1) CN112513280A (es)
BR (1) BR112020024033A2 (es)
CA (1) CA3101424A1 (es)
GB (1) GB201808663D0 (es)
MX (1) MX2020012627A (es)
WO (1) WO2019224536A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111868047A (zh) 2017-12-21 2020-10-30 齐默尔根公司 荆芥内半缩醛氧化还原酶、荆芥内半缩醛合酶和能够产生荆芥内酯的微生物
WO2022106638A1 (en) * 2020-11-19 2022-05-27 Danmarks Tekniske Universitet Methods for production of cis-trans-nepetalactol and iridoids
CN113151205A (zh) * 2021-04-20 2021-07-23 华东理工大学 醇脱氢酶突变体及其在环状萜烯酮合成中的应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0230217D0 (en) * 2002-12-27 2003-02-05 Biotica Tech Ltd Borrelidin-producing polyketide synthase and its uses
ES2535011T3 (es) * 2008-02-15 2015-05-04 Ceres Inc. Tolerancia a la sequía y al calor en plantas
WO2016029187A2 (en) * 2014-08-21 2016-02-25 Givaudan Sa Methods for production of oxygenated terpenes
WO2016107920A1 (en) * 2014-12-30 2016-07-07 Evolva Sa Production of macrocyclic diterpenes in recombinant hosts
CN111868047A (zh) * 2017-12-21 2020-10-30 齐默尔根公司 荆芥内半缩醛氧化还原酶、荆芥内半缩醛合酶和能够产生荆芥内酯的微生物

Also Published As

Publication number Publication date
CN112513280A (zh) 2021-03-16
JP2021525098A (ja) 2021-09-24
BR112020024033A2 (pt) 2021-02-23
US20210207183A1 (en) 2021-07-08
GB201808663D0 (en) 2018-07-11
CA3101424A1 (en) 2019-11-28
KR20210015897A (ko) 2021-02-10
EP3802837A1 (en) 2021-04-14
WO2019224536A1 (en) 2019-11-28

Similar Documents

Publication Publication Date Title
MX2020012627A (es) Metodo para la produccion de compuestos monoterpenoides.
MY191029A (en) Novel polypeptide and method of producing imp using the same
PH12020500115A1 (en) cAMP RECEPTOR PROTEIN VARIANT AND METHOD OF PRODUCING L-AMINO ACID USING THE SAME
MX2023009109A (es) Una variante de isopropilmalato sintasa novedosa y un procedimiento de produccion de l-leucina usando la misma.
AU2018293281A1 (en) Novel aspartokinase mutant and method for production of L-amino acid using same
MY195583A (en) Modified Homoserine Dehydrogenase and Method for Producing Homoserine Or L-Amino Acid Derived from Homoserine using the same
PH12020551031A1 (en) Modified homoserine dehydrogenase and method for producing homoserine or l-amino acid derived from homoserine using the same
IN2014DN10709A (es)
PH12020500113A1 (en) Camp receptor protein variant and method of producing l-amino acid using the same
NZ731727A (en) Method for producing a protein hydrolysate
PH12020550976A1 (en) Camp receptor protein variant and method of producing l-amino acid using the same
MX2019007411A (es) Reuso de enzimas en glucomanipulacion in vitro de anticuerpos.
MX2020007037A (es) Un microorganismo del genero corynebacterium que produce l-aminoacidos y un procedimiento para producir l-aminoacidos mediante el uso del mismo.
MX2020008738A (es) Metodo de produccion.
DE602004024686D1 (de) Cephalosporin-c-acylase-mutante und verfahren zur herstellung von 7-aca damit
MX2021010291A (es) Método para reducir la lactosa a temperaturas altas.
MX2021012296A (es) Microorganismo que produce l-aminoacido y procedimiento de produccion de l-aminoacido mediante el uso del mismo.
MY193458A (en) Microorganism for producing a mycosporine-like amino acid and method for producing a mycosporine-like amino acid using the same
MX2022005331A (es) Rodamiento con separacion, ensamblaje y metodo para su fabricacion y uso.
WO2019222226A8 (en) Production of 2-keto-3-deoxy-d-gluconic acid in filamentous fungi
WO2018207184A3 (en) Methods of purifying antibodies
WO2020234205A3 (de) Verfahren zur herstellung eines leitfähigen pflanzlichen materials, leitfähiges pflanzliches material und verwendung
MX2021015842A (es) Polipeptido variante de dihidrodipicolinato reductasa y procedimiento de produccion de l-treonina mediante el uso del mismo.
WO2023044006A8 (en) Compositions and methods for producing circular polyribonucleotides
MY191429A (en) Modified microorganism with improved biomass separation behaviour