MX2020012440A - Metodo epigenetico para evaluar la exposicion al sol. - Google Patents
Metodo epigenetico para evaluar la exposicion al sol.Info
- Publication number
- MX2020012440A MX2020012440A MX2020012440A MX2020012440A MX2020012440A MX 2020012440 A MX2020012440 A MX 2020012440A MX 2020012440 A MX2020012440 A MX 2020012440A MX 2020012440 A MX2020012440 A MX 2020012440A MX 2020012440 A MX2020012440 A MX 2020012440A
- Authority
- MX
- Mexico
- Prior art keywords
- sun exposure
- assess
- skin
- skin cells
- individual
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/154—Methylation markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Pathology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Cosmetics (AREA)
- Materials For Photolithography (AREA)
Abstract
La presente invención se refiere a un método para obtener información útil para determinar el efecto de la exposición aguada al sol sobre la piel de un individuo, el método está caracterizado porque comprende los pasos de: (a) obtener ADN genómico a partir de células cutáneas ex vivo derivadas del individuo, en donde las células cutáneas ex vivo incluyen células cutáneas epidérmicas ex vivo; y (b) observar la metilación de cistosina de al menos dos loci CpG en el ADN genómico seleccionado de un grupo que consiste de 78 locis CpGs, de tal forma que se obtenga la información útil para determinar el efecto de la exposición aguada al sol en la piel.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP18177975 | 2018-06-15 | ||
PCT/EP2019/065415 WO2019238792A1 (en) | 2018-06-15 | 2019-06-12 | Epigenetic method to assess sun exposure |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2020012440A true MX2020012440A (es) | 2022-03-29 |
Family
ID=62705398
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2020012440A MX2020012440A (es) | 2018-06-15 | 2019-06-12 | Metodo epigenetico para evaluar la exposicion al sol. |
Country Status (5)
Country | Link |
---|---|
US (1) | US20210214795A1 (es) |
EP (1) | EP3775285B1 (es) |
CN (1) | CN112166202A (es) |
MX (1) | MX2020012440A (es) |
WO (1) | WO2019238792A1 (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3854881A1 (en) * | 2020-01-22 | 2021-07-28 | Beiersdorf Ag | Classifying subjects based on their biological response to uv irradiation |
WO2022258310A1 (en) | 2021-06-07 | 2022-12-15 | Unilever Ip Holdings B.V. | Epigenetic method to detect uvr-induced skin damage |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2013003465A2 (en) * | 2011-06-28 | 2013-01-03 | Avicena Group, Inc. | Methods and compositions for treating skin |
AU2012321248A1 (en) * | 2011-09-30 | 2014-04-24 | Genentech, Inc. | Diagnostic methylation markers of epithelial or mesenchymal phenotype and response to EGFR kinase inhibitor in tumours or tumour cells |
US11613784B2 (en) * | 2016-03-25 | 2023-03-28 | The Trustees Of Columbia University In The City Of New York | Next-generation biomarkers to detect sun damage and predict skin cancer risk |
-
2019
- 2019-06-12 WO PCT/EP2019/065415 patent/WO2019238792A1/en unknown
- 2019-06-12 CN CN201980035571.XA patent/CN112166202A/zh active Pending
- 2019-06-12 US US17/057,775 patent/US20210214795A1/en not_active Abandoned
- 2019-06-12 MX MX2020012440A patent/MX2020012440A/es unknown
- 2019-06-12 EP EP19729072.9A patent/EP3775285B1/en active Active
Also Published As
Publication number | Publication date |
---|---|
US20210214795A1 (en) | 2021-07-15 |
WO2019238792A1 (en) | 2019-12-19 |
EP3775285B1 (en) | 2021-10-06 |
EP3775285A1 (en) | 2021-02-17 |
CN112166202A (zh) | 2021-01-01 |
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