MX2019014848A - Anti-cd38 antibodies and fusions with attenuated alpha-2b interferon. - Google Patents

Anti-cd38 antibodies and fusions with attenuated alpha-2b interferon.

Info

Publication number
MX2019014848A
MX2019014848A MX2019014848A MX2019014848A MX2019014848A MX 2019014848 A MX2019014848 A MX 2019014848A MX 2019014848 A MX2019014848 A MX 2019014848A MX 2019014848 A MX2019014848 A MX 2019014848A MX 2019014848 A MX2019014848 A MX 2019014848A
Authority
MX
Mexico
Prior art keywords
antibodies
interferon
fusions
alpha
well
Prior art date
Application number
MX2019014848A
Other languages
Spanish (es)
Inventor
Clarke Adam
Gerard Doyle Anthony
Pollard Matthew
Behrens Collette
Yamagishi Tetsuo
L Pogue Sarah
Taura Tetsuya
S Jr Wilson David
Original Assignee
Teva Pharmaceuticals Australia Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teva Pharmaceuticals Australia Pty Ltd filed Critical Teva Pharmaceuticals Australia Pty Ltd
Priority to MX2019014848A priority Critical patent/MX2019014848A/en
Publication of MX2019014848A publication Critical patent/MX2019014848A/en

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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

The present invention relates to antibodies specifically binding to CD38, as well as constructs comprising such antibodies fused with attenuated interferon-alpha-2b proteins. Said mixture is useful to inhibit proliferation in cancer cells expressing both CD38 and the IFN-alpha2b receptor, as well as to induce apoptosis in such cells. Also, it serves as the basis for the treatment of underlying cancer.
MX2019014848A 2015-10-28 2015-10-28 Anti-cd38 antibodies and fusions with attenuated alpha-2b interferon. MX2019014848A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
MX2019014848A MX2019014848A (en) 2015-10-28 2015-10-28 Anti-cd38 antibodies and fusions with attenuated alpha-2b interferon.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
MX2019014848A MX2019014848A (en) 2015-10-28 2015-10-28 Anti-cd38 antibodies and fusions with attenuated alpha-2b interferon.

Publications (1)

Publication Number Publication Date
MX2019014848A true MX2019014848A (en) 2020-02-12

Family

ID=72832995

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2019014848A MX2019014848A (en) 2015-10-28 2015-10-28 Anti-cd38 antibodies and fusions with attenuated alpha-2b interferon.

Country Status (1)

Country Link
MX (1) MX2019014848A (en)

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