MX2019006749A - Compuestos activadores de senescencia celular. - Google Patents
Compuestos activadores de senescencia celular.Info
- Publication number
- MX2019006749A MX2019006749A MX2019006749A MX2019006749A MX2019006749A MX 2019006749 A MX2019006749 A MX 2019006749A MX 2019006749 A MX2019006749 A MX 2019006749A MX 2019006749 A MX2019006749 A MX 2019006749A MX 2019006749 A MX2019006749 A MX 2019006749A
- Authority
- MX
- Mexico
- Prior art keywords
- cellular senescence
- activating compounds
- senescence
- guayulines
- genotoxicity
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 230000003213 activating effect Effects 0.000 title 1
- 230000010094 cellular senescence Effects 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 231100000135 cytotoxicity Toxicity 0.000 abstract 1
- 230000003013 cytotoxicity Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 231100000025 genetic toxicology Toxicity 0.000 abstract 1
- 230000001738 genotoxic effect Effects 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 230000000527 lymphocytic effect Effects 0.000 abstract 1
- 230000009758 senescence Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/76—Unsaturated compounds containing keto groups
- C07C59/80—Unsaturated compounds containing keto groups containing rings other than six-membered aromatic rings
- C07C59/82—Unsaturated compounds containing keto groups containing rings other than six-membered aromatic rings the keto group being part of a ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
- A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/40—Ortho- or ortho- and peri-condensed systems containing four condensed rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/52—Ortho- or ortho- and peri-condensed systems containing five condensed rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MX2019006749A MX2019006749A (es) | 2019-06-10 | 2019-06-10 | Compuestos activadores de senescencia celular. |
| EP20822864.3A EP3988521A4 (en) | 2019-06-10 | 2020-06-10 | COMPOUNDS ACTIVATING CELLULAR SENESCENCE |
| US17/618,348 US20220233553A1 (en) | 2019-06-10 | 2020-06-10 | Cellular senescence activating compounds |
| JP2021573470A JP2022536698A (ja) | 2019-06-10 | 2020-06-10 | 細胞老化活性化化合物 |
| PCT/MX2020/050010 WO2020251346A1 (es) | 2019-06-10 | 2020-06-10 | Compuestos activadores de senescencia celular |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MX2019006749A MX2019006749A (es) | 2019-06-10 | 2019-06-10 | Compuestos activadores de senescencia celular. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2019006749A true MX2019006749A (es) | 2022-11-28 |
Family
ID=73781643
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2019006749A MX2019006749A (es) | 2019-06-10 | 2019-06-10 | Compuestos activadores de senescencia celular. |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20220233553A1 (https=) |
| EP (1) | EP3988521A4 (https=) |
| JP (1) | JP2022536698A (https=) |
| MX (1) | MX2019006749A (https=) |
| WO (1) | WO2020251346A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022133477A1 (en) * | 2020-12-18 | 2022-06-23 | Bridgestone Corporation | Modified guayule resin product and related processes |
| BR112023015924A2 (pt) * | 2021-02-08 | 2023-10-17 | Bridgestone Corp | Produto de resina de guaiule modificada, e, processo para preparar um produto de resina de guaiule modificada |
| GB2642547A (en) * | 2024-07-12 | 2026-01-14 | Univ Durham | Compounds for use in senotherapy |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1809364B (zh) | 2003-06-23 | 2010-06-16 | 杰龙公司 | 增加端粒酶活性的组合物和方法 |
| CA2795981C (en) | 2009-05-18 | 2017-06-27 | Geron Corporation | Compositions and methods for increasing telomerase activity |
-
2019
- 2019-06-10 MX MX2019006749A patent/MX2019006749A/es unknown
-
2020
- 2020-06-10 WO PCT/MX2020/050010 patent/WO2020251346A1/es not_active Ceased
- 2020-06-10 JP JP2021573470A patent/JP2022536698A/ja active Pending
- 2020-06-10 EP EP20822864.3A patent/EP3988521A4/en not_active Withdrawn
- 2020-06-10 US US17/618,348 patent/US20220233553A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP3988521A1 (en) | 2022-04-27 |
| WO2020251346A1 (es) | 2020-12-17 |
| JP2022536698A (ja) | 2022-08-18 |
| US20220233553A1 (en) | 2022-07-28 |
| EP3988521A4 (en) | 2023-07-05 |
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