MX2019001395A - Clon de adnc del virus del sindrome reproductivo y respiratorio porcino y usos del mismo. - Google Patents

Clon de adnc del virus del sindrome reproductivo y respiratorio porcino y usos del mismo.

Info

Publication number
MX2019001395A
MX2019001395A MX2019001395A MX2019001395A MX2019001395A MX 2019001395 A MX2019001395 A MX 2019001395A MX 2019001395 A MX2019001395 A MX 2019001395A MX 2019001395 A MX2019001395 A MX 2019001395A MX 2019001395 A MX2019001395 A MX 2019001395A
Authority
MX
Mexico
Prior art keywords
prrsv
attenuated
cdna clone
respiratory syndrome
syndrome virus
Prior art date
Application number
MX2019001395A
Other languages
English (en)
Inventor
Gibert Pérez Xavier
Sitjà Arnau Marta
Mar Fenech Martínez Maria
Francisco Elena Fito Santiago
Martin Garcia Susana
Original Assignee
Hipra Scient S L U
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hipra Scient S L U filed Critical Hipra Scient S L U
Publication of MX2019001395A publication Critical patent/MX2019001395A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1096—Processes for the isolation, preparation or purification of DNA or RNA cDNA Synthesis; Subtracted cDNA library construction, e.g. RT, RT-PCR
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Abstract

La presente invención se refiere a un método para preparar clones infecciosos de ADNc basados en el genoma de un virus atenuado del síndrome respiratorio y reproductivo porcino (PRRSV) y usos de los mismos en la preparación de vacunas eficaces y con seguridad mejorada contra PRRSV. La invención comprende además un clon infeccioso de ADNc obtenible mediante dicho método. La invención proporciona además un PRRSV atenuado modificado y composiciones inmunogénicas y vacunas que comprenden ese PRRSV atenuado. La presente invención proporciona además el PRRSV atenuado para uso en la profilaxis y/o el tratamiento de infecciones por PRRSV, y el PRRSV atenuado para uso como vacuna o medicamento en la profilaxis y/o el tratamiento de infecciones por PRRSV.
MX2019001395A 2016-08-05 2017-07-31 Clon de adnc del virus del sindrome reproductivo y respiratorio porcino y usos del mismo. MX2019001395A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16382391 2016-08-05
PCT/EP2017/069329 WO2018024677A1 (en) 2016-08-05 2017-07-31 PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS cDNA CLONE AND USES THEREOF

Publications (1)

Publication Number Publication Date
MX2019001395A true MX2019001395A (es) 2019-06-17

Family

ID=56682075

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2019001395A MX2019001395A (es) 2016-08-05 2017-07-31 Clon de adnc del virus del sindrome reproductivo y respiratorio porcino y usos del mismo.

Country Status (9)

Country Link
US (1) US11332739B2 (es)
EP (1) EP3493838A1 (es)
JP (1) JP6986078B2 (es)
AR (1) AR109291A1 (es)
BR (1) BR112019000887A2 (es)
CA (1) CA3032891A1 (es)
MX (1) MX2019001395A (es)
PH (1) PH12019550018A1 (es)
WO (1) WO2018024677A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018024677A1 (en) * 2016-08-05 2018-02-08 Hipra Scientific, S.L.U. PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS cDNA CLONE AND USES THEREOF

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0839912A1 (en) 1996-10-30 1998-05-06 Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
CA2290220C (en) 1998-12-22 2013-11-19 Pfizer Products Inc. An infectious cdna clone of north american porcine reproductive and respiratory syndrome (prrs) virus and uses thereof
KR100872840B1 (ko) 2004-07-09 2008-12-22 (주)씨아이디 돼지생식기호흡기증후군 바이러스에 대한 전체-길이의감염성이 있는 cDNA 클론 및 이의 용도
PT1904631E (pt) 2005-06-24 2012-07-16 Univ Minnesota Vírus srrp, clones infecciosos, os seus mutantes e processos de utilização
WO2011153351A2 (en) 2010-06-02 2011-12-08 Virginia Tech Intellectual Properties, Inc. Novel modified live-attenuated vaccines (mlv) and subunit vaccines created by dna shuffling against porcine reproductive and respiratory syndrome virus (prrsv)
WO2013017570A1 (en) 2011-07-29 2013-02-07 Boehringer Ingelheim Vetmedica Gmbh Novel prrs virus inducing type i interferon in susceptible cells
JP6386999B2 (ja) * 2012-05-17 2018-09-05 ゾエティス・エルエルシー ブタ生殖および呼吸症候群（ｐｒｒｓ）ウイルスに対する離乳前の効果的なワクチン接種
MX2020010248A (es) 2013-12-20 2020-10-16 Boehringer Ingelheim Vetmedica Gmbh Variante del virus prrs, clon de adnc del virus europeo y sus usos.
WO2018024677A1 (en) * 2016-08-05 2018-02-08 Hipra Scientific, S.L.U. PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS cDNA CLONE AND USES THEREOF

Also Published As

Publication number Publication date
US11332739B2 (en) 2022-05-17
JP2019526278A (ja) 2019-09-19
AR109291A1 (es) 2018-11-14
BR112019000887A2 (pt) 2019-04-30
WO2018024677A1 (en) 2018-02-08
EP3493838A1 (en) 2019-06-12
US20190177721A1 (en) 2019-06-13
CA3032891A1 (en) 2018-02-08
PH12019550018A1 (en) 2019-11-04
JP6986078B2 (ja) 2021-12-22

Similar Documents

Publication Publication Date Title
EP4233898A3 (en) Influenza mrna vaccines
PH12018500127A1 (en) Vaccine compositions
WO2017214596A8 (en) Compositions and methods for preventing and treating zika virus infection
MX2013013906A (es) Vacunas combinadas para prevencion de infecciones por virus porcino.
PH12019500989A1 (en) Vaccine against porcine parvovirus and porcine reproductive and respiratory syndrome virus and methods of production thereof
PH12018000197A1 (en) Hand, foot, and mouth vaccines and methods of manufacture and use thereof
PH12017501370A1 (en) Bivalent swine influenza virus vaccine
WO2014150822A3 (en) Porcine reproductive and respiratory syndrome virus, compositions, vaccine and methods of use
MX2019007349A (es) Vacuna combinada para cerdos.
WO2017156511A8 (en) Live attenuated zika virus vaccine
PH12018501368A1 (en) M hyo multivalent vaccine and uses thereof
NZ618158A (en) Compositions and methods for administration of vaccines against dengue virus
MX2018015506A (es) Vacuna contra virus de bronquitis infecciosa.
MX2018006416A (es) Metodos para el tratamiento, prevencion y diagnostico de infeccion por el virus de la diarrea epidemica porcina.
MX2021006997A (es) Arilmetilureas y heteroarilmetilureas sustituidas, análogos de las mismas y métodos para utilizar las mismas.
PH12019501320A1 (en) Effective vaccination against european strains of porcine reproductive and respiratory syndrome (prrs) virus prior to weaning
PH12018502436A1 (en) Multivalent vaccines major swine viral diseases
PH12019550018A1 (en) Porcine reproductive and respiratory syndrome virus cdna clone and uses thereof
MX2022008809A (es) Virus de vacuna del sindrome respiratorio y reproductivo porcino.
MX2017012389A (es) Vacuna del virus de la parotiditis recombinante jeryl lynn2.
JOP20190214A1 (ar) ثنائي هيدرو إيندين-?-كربوكساميدات ونظائر منها بها استبدال، وطرق تستخدمها
WO2016012406A3 (en) Attenuated strain of prrs and potential use in immunising preparations
GB202304890D0 (en) Porcine reproductive and respiratory syndrome virus, compositions, vaccine and methods of use
MX2021015449A (es) Vector recombinante y composicion inmunogenica para la prevencion de la enfermedad causada por virus sincitial respiratorio.
MX2021015938A (es) Virus para vacuna contra el síndrome respiratorio y reproductivo porcino.