MX2018012562A - Formulacion de granulos para administracion oral. - Google Patents
Formulacion de granulos para administracion oral.Info
- Publication number
- MX2018012562A MX2018012562A MX2018012562A MX2018012562A MX2018012562A MX 2018012562 A MX2018012562 A MX 2018012562A MX 2018012562 A MX2018012562 A MX 2018012562A MX 2018012562 A MX2018012562 A MX 2018012562A MX 2018012562 A MX2018012562 A MX 2018012562A
- Authority
- MX
- Mexico
- Prior art keywords
- granule formulation
- oral administration
- granule
- cariprazine hydrochloride
- formulation
- Prior art date
Links
- 239000008187 granular material Substances 0.000 title abstract 4
- 238000009472 formulation Methods 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 3
- GPPJWWMREQHLQT-BHQIMSFRSA-N cariprazine hydrochloride Chemical compound Cl.C1C[C@@H](NC(=O)N(C)C)CC[C@@H]1CCN1CCN(C=2C(=C(Cl)C=CC=2)Cl)CC1 GPPJWWMREQHLQT-BHQIMSFRSA-N 0.000 abstract 2
- 229960003429 cariprazine hydrochloride Drugs 0.000 abstract 2
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 239000008101 lactose Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La invención se refiere a una formulación de gránulos que permite que el clorhidrato de cariprazina se almacene de manera estable. La solución proporciona una formulación de gránulos que contiene clorhidrato de cariprazina, en donde dicha formulación de gránulos contiene lactosa como diluyente primario.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP16165247.4A EP3231418A1 (en) | 2016-04-14 | 2016-04-14 | Granule formulation for oral administration |
PCT/IB2017/052129 WO2017178999A1 (en) | 2016-04-14 | 2017-04-13 | Granule formulation for oral administration |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2018012562A true MX2018012562A (es) | 2019-06-10 |
Family
ID=55802213
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2018012562A MX2018012562A (es) | 2016-04-14 | 2017-04-13 | Formulacion de granulos para administracion oral. |
Country Status (13)
Country | Link |
---|---|
US (1) | US20190117647A1 (es) |
EP (2) | EP3231418A1 (es) |
JP (1) | JP2019511513A (es) |
KR (1) | KR20180131579A (es) |
CN (1) | CN109069429A (es) |
AU (1) | AU2017250640A1 (es) |
BR (1) | BR112018070615A2 (es) |
CA (1) | CA3020981A1 (es) |
EA (1) | EA201892235A1 (es) |
IL (1) | IL262204A (es) |
MX (1) | MX2018012562A (es) |
TN (1) | TN2018000326A1 (es) |
WO (1) | WO2017178999A1 (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK2317852T3 (en) | 2008-07-16 | 2015-03-23 | Richter Gedeon Nyrt | PHARMACEUTICAL FORMULATIONS CONTAINING dopamine receptor ligands |
US11274087B2 (en) | 2016-07-08 | 2022-03-15 | Richter Gedeon Nyrt. | Industrial process for the preparation of cariprazine |
US11273156B2 (en) * | 2018-11-20 | 2022-03-15 | Aurobindo Pharma Ltd | Stable cariprazine formulations for oral use |
US11547707B2 (en) | 2019-04-10 | 2023-01-10 | Richter Gedeon Nyrt. | Carbamoyl cyclohexane derivatives for treating autism spectrum disorder |
US11344503B2 (en) | 2019-12-13 | 2022-05-31 | Halo Science LLC | Cariprazine release formulations |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU227534B1 (en) | 2003-08-04 | 2011-08-29 | Richter Gedeon Nyrt | (thio)carbamoyl-cyclohexane derivatives, process for producing them and pharmaceutical compositions containing them |
EA023972B1 (ru) * | 2008-02-21 | 2016-08-31 | Рихтер Гедеон Нирт. | Стабильный твёрдый препарат карипразина для перорального введения и способ его получения |
DK2317852T3 (en) * | 2008-07-16 | 2015-03-23 | Richter Gedeon Nyrt | PHARMACEUTICAL FORMULATIONS CONTAINING dopamine receptor ligands |
-
2016
- 2016-04-14 EP EP16165247.4A patent/EP3231418A1/en not_active Withdrawn
-
2017
- 2017-04-13 WO PCT/IB2017/052129 patent/WO2017178999A1/en active Application Filing
- 2017-04-13 US US16/092,574 patent/US20190117647A1/en not_active Abandoned
- 2017-04-13 JP JP2018551926A patent/JP2019511513A/ja active Pending
- 2017-04-13 BR BR112018070615A patent/BR112018070615A2/pt not_active Application Discontinuation
- 2017-04-13 EA EA201892235A patent/EA201892235A1/ru unknown
- 2017-04-13 CN CN201780023221.2A patent/CN109069429A/zh active Pending
- 2017-04-13 TN TNP/2018/000326A patent/TN2018000326A1/en unknown
- 2017-04-13 AU AU2017250640A patent/AU2017250640A1/en not_active Abandoned
- 2017-04-13 MX MX2018012562A patent/MX2018012562A/es unknown
- 2017-04-13 KR KR1020187030642A patent/KR20180131579A/ko not_active Application Discontinuation
- 2017-04-13 CA CA3020981A patent/CA3020981A1/en not_active Abandoned
- 2017-04-13 EP EP17717880.3A patent/EP3442508A1/en not_active Withdrawn
-
2018
- 2018-10-08 IL IL262204A patent/IL262204A/en unknown
Also Published As
Publication number | Publication date |
---|---|
KR20180131579A (ko) | 2018-12-10 |
EP3231418A1 (en) | 2017-10-18 |
BR112018070615A2 (pt) | 2019-02-05 |
IL262204A (en) | 2018-11-29 |
WO2017178999A1 (en) | 2017-10-19 |
JP2019511513A (ja) | 2019-04-25 |
US20190117647A1 (en) | 2019-04-25 |
EA201892235A1 (ru) | 2019-03-29 |
TN2018000326A1 (en) | 2020-01-16 |
CN109069429A (zh) | 2018-12-21 |
AU2017250640A1 (en) | 2018-11-08 |
CA3020981A1 (en) | 2017-10-19 |
EP3442508A1 (en) | 2019-02-20 |
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