MX2016012258A - Dosificacion optima de un conjugado del farmaco del anticuerpo-cd19. - Google Patents
Dosificacion optima de un conjugado del farmaco del anticuerpo-cd19.Info
- Publication number
- MX2016012258A MX2016012258A MX2016012258A MX2016012258A MX2016012258A MX 2016012258 A MX2016012258 A MX 2016012258A MX 2016012258 A MX2016012258 A MX 2016012258A MX 2016012258 A MX2016012258 A MX 2016012258A MX 2016012258 A MX2016012258 A MX 2016012258A
- Authority
- MX
- Mexico
- Prior art keywords
- antibody drug
- drug conjugate
- optimal dosing
- dosing
- optimal
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3061—Blood cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6851—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell
- A61K47/6867—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell the tumour determinant being from a cell of a blood cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
- A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
- A61K47/6811—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
- A61K47/6817—Toxins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
Abstract
La presente invención describe métodos de dosificación óptima de los conjugados del fármaco del anticuerpo-CD19.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201461976790P | 2014-04-08 | 2014-04-08 | |
PCT/US2015/024732 WO2015157297A1 (en) | 2014-04-08 | 2015-04-07 | Optimal dosing of a cd19-antibody drug conjugate |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2016012258A true MX2016012258A (es) | 2017-01-06 |
Family
ID=54288332
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2016012258A MX2016012258A (es) | 2014-04-08 | 2015-04-07 | Dosificacion optima de un conjugado del farmaco del anticuerpo-cd19. |
Country Status (12)
Country | Link |
---|---|
US (1) | US20170182178A1 (es) |
EP (1) | EP3129052B1 (es) |
JP (1) | JP2017512801A (es) |
KR (1) | KR20160141727A (es) |
CN (1) | CN106170300A (es) |
AU (1) | AU2015244004A1 (es) |
CA (1) | CA2941154A1 (es) |
EA (1) | EA201692016A1 (es) |
IL (1) | IL247526A0 (es) |
MX (1) | MX2016012258A (es) |
SG (1) | SG11201607133QA (es) |
WO (1) | WO2015157297A1 (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MA45625A (fr) * | 2016-07-08 | 2019-05-15 | Genmab As | Nouveaux régimes posologiques pour conjugués anticorps-médicaments à base d'anticorps anti-axl |
WO2018229222A1 (en) * | 2017-06-14 | 2018-12-20 | Adc Therapeutics Sa | Dosage regimes for the administration of an anti-cd19 adc |
CN109069584A (zh) * | 2017-06-29 | 2018-12-21 | 成都华创生物技术有限公司 | 一种trail类蛋白持续抑制肿瘤细胞生长的给药方法 |
US11672827B2 (en) | 2017-12-23 | 2023-06-13 | Uwell Biopharma Inc. | Pharmaceutical chimeric receptor composition and method thereof |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT2489364E (pt) * | 2003-11-06 | 2015-04-16 | Seattle Genetics Inc | Compostos de monometilvalina conjugados com anticorpos |
JP5727786B2 (ja) * | 2007-10-19 | 2015-06-03 | シアトル ジェネティクス,インコーポレーテッド | Cd19結合性物質およびその使用 |
ME02919B (me) * | 2010-06-15 | 2018-04-20 | Genmab As | Konjugati humanog antitijela sa lijekom protiv tkivnog faktora |
AU2011316917B2 (en) * | 2010-10-22 | 2016-02-25 | Seagen Inc. | Synergistic effects between auristatin-based antibody drug conjugates and inhibitors of the PI3K-AKT mTOR pathway |
WO2012162561A2 (en) * | 2011-05-24 | 2012-11-29 | Zyngenia, Inc. | Multivalent and monovalent multispecific complexes and their uses |
-
2015
- 2015-04-07 KR KR1020167027123A patent/KR20160141727A/ko unknown
- 2015-04-07 US US15/129,727 patent/US20170182178A1/en not_active Abandoned
- 2015-04-07 WO PCT/US2015/024732 patent/WO2015157297A1/en active Application Filing
- 2015-04-07 SG SG11201607133QA patent/SG11201607133QA/en unknown
- 2015-04-07 MX MX2016012258A patent/MX2016012258A/es unknown
- 2015-04-07 CA CA2941154A patent/CA2941154A1/en not_active Abandoned
- 2015-04-07 EP EP15775944.0A patent/EP3129052B1/en active Active
- 2015-04-07 EA EA201692016A patent/EA201692016A1/ru unknown
- 2015-04-07 CN CN201580019099.2A patent/CN106170300A/zh active Pending
- 2015-04-07 JP JP2016559853A patent/JP2017512801A/ja active Pending
- 2015-04-07 AU AU2015244004A patent/AU2015244004A1/en not_active Abandoned
-
2016
- 2016-08-29 IL IL247526A patent/IL247526A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
EA201692016A1 (ru) | 2017-01-30 |
EP3129052A4 (en) | 2017-11-15 |
KR20160141727A (ko) | 2016-12-09 |
JP2017512801A (ja) | 2017-05-25 |
SG11201607133QA (en) | 2016-09-29 |
AU2015244004A1 (en) | 2016-09-15 |
CN106170300A (zh) | 2016-11-30 |
EP3129052A1 (en) | 2017-02-15 |
IL247526A0 (en) | 2016-11-30 |
EP3129052B1 (en) | 2020-06-03 |
US20170182178A1 (en) | 2017-06-29 |
WO2015157297A1 (en) | 2015-10-15 |
CA2941154A1 (en) | 2015-10-15 |
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