MX2016006170A - Metodo para hacer un hidrogel, hidrogel y formulacion para portadores y/o sustitutos de tejidos conectivos obtenidos utizando tal metodo. - Google Patents
Metodo para hacer un hidrogel, hidrogel y formulacion para portadores y/o sustitutos de tejidos conectivos obtenidos utizando tal metodo.Info
- Publication number
- MX2016006170A MX2016006170A MX2016006170A MX2016006170A MX2016006170A MX 2016006170 A MX2016006170 A MX 2016006170A MX 2016006170 A MX2016006170 A MX 2016006170A MX 2016006170 A MX2016006170 A MX 2016006170A MX 2016006170 A MX2016006170 A MX 2016006170A
- Authority
- MX
- Mexico
- Prior art keywords
- hydrogel
- polymer
- aqueous solution
- substitute
- carriers
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/26—Mixtures of macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/52—Hydrogels or hydrocolloids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J3/00—Processes of treating or compounding macromolecular substances
- C08J3/02—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques
- C08J3/03—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in aqueous media
- C08J3/075—Macromolecular gels
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L71/00—Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
- C08L71/02—Polyalkylene oxides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/06—Flowable or injectable implant compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/06—Materials or treatment for tissue regeneration for cartilage reconstruction, e.g. meniscus
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2371/00—Characterised by the use of polyethers obtained by reactions forming an ether link in the main chain; Derivatives of such polymers
- C08J2371/02—Polyalkylene oxides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- Zoology (AREA)
- Botany (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Polymers & Plastics (AREA)
- Materials For Medical Uses (AREA)
- Medicinal Preparation (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Polymerisation Methods In General (AREA)
Abstract
Un método para hacer un hidrogel para utilizarse como portadores y/o sustitutos de los tejidos conectivos, que comprende los pasos de proporcionar una cantidad predeterminada de una solución acuosa, agregar y solubilizar una cantidad predeterminada de un primer polímero soluble en agua polimerizable mediante radiación electromagnética en la solución acuosa, agregar una cantidad predeterminada de un agente regulador de la polimerización a la solución acuosa, para regular la polimerización del primer polímero para obtener una mezcla, aplicar una radiación electromagnética a la mezcla, para lograr la polimerización del primer polímero con una viscosidad predeterminada y obtener un hidrogel estéril. Un segundo polímero soluble en agua polimerizable con radiación, que es diferente del primero, y que no es reactivo con el regulador, se agrega a la solución acuosa antes de la aplicación de la radiación electromagnética, las cantidades del agente regulador con relación al primer polímero y al segundo polímero se seleccionan para permitir el control de la consistencia y viscosidad finales del hidrogel estéril. Un hidrogel y una formulación diseñados para utilizarse como portadores y/o un sustituto de los tejidos conectivos.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITVI20140011 | 2014-01-20 | ||
| PCT/IB2015/050389 WO2015107502A1 (en) | 2014-01-20 | 2015-01-19 | Method of making a hydrogel, hydrogel and formulation for carriers and/or substitute of connective tissues obtained using such method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2016006170A true MX2016006170A (es) | 2016-09-13 |
Family
ID=50116136
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2016006170A MX2016006170A (es) | 2014-01-20 | 2015-01-19 | Metodo para hacer un hidrogel, hidrogel y formulacion para portadores y/o sustitutos de tejidos conectivos obtenidos utizando tal metodo. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20160317705A1 (es) |
| EP (1) | EP3096804B1 (es) |
| CN (1) | CN105934258A (es) |
| ES (1) | ES2771856T3 (es) |
| MX (1) | MX2016006170A (es) |
| PT (1) | PT3096804T (es) |
| RU (1) | RU2016133447A (es) |
| WO (1) | WO2015107502A1 (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL248472A0 (en) | 2016-10-13 | 2017-01-31 | Zion Karmon Ben | Devices for tissue growth |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5540033A (en) | 1994-01-10 | 1996-07-30 | Cambrex Hydrogels | Integrated Manufacturing process for hydrogels |
| US8303981B2 (en) * | 1996-08-27 | 2012-11-06 | Baxter International Inc. | Fragmented polymeric compositions and methods for their use |
| US7862831B2 (en) * | 2002-10-09 | 2011-01-04 | Synthasome, Inc. | Method and material for enhanced tissue-biomaterial integration |
| CN1424115A (zh) * | 2002-12-06 | 2003-06-18 | 暨南大学 | 组织工程支架材料及其制备方法 |
| US20050220882A1 (en) * | 2004-03-04 | 2005-10-06 | Wilson Pritchard | Materials for medical implants and occlusive devices |
| WO2007140312A2 (en) * | 2006-05-25 | 2007-12-06 | The General Hospital Corporation | Anti-cross-linking agents and methods for inhibiting cross-linking of injectable hydrogel formulations |
| US7935363B2 (en) * | 2006-12-12 | 2011-05-03 | Synthasome, Inc. | Composite material for tissue repair |
| CN101590028B (zh) * | 2009-04-16 | 2011-06-01 | 中国人民解放军第二军医大学 | 包含妥洛特罗的水凝胶贴剂及其制备方法 |
| WO2013011503A1 (en) * | 2011-07-20 | 2013-01-24 | Theracoat Ltd. | Production of thermoreversible hydrogels for therapeutic applications |
| DK2836200T3 (da) * | 2012-04-08 | 2020-09-21 | Urogen Pharma Ltd | Termoreversible hydrogelpræparater til anvendelse i behandlingen af lidelser i urothelium |
-
2015
- 2015-01-19 CN CN201580004965.0A patent/CN105934258A/zh not_active Withdrawn
- 2015-01-19 RU RU2016133447A patent/RU2016133447A/ru not_active Application Discontinuation
- 2015-01-19 EP EP15707784.3A patent/EP3096804B1/en active Active
- 2015-01-19 PT PT157077843T patent/PT3096804T/pt unknown
- 2015-01-19 MX MX2016006170A patent/MX2016006170A/es active IP Right Grant
- 2015-01-19 WO PCT/IB2015/050389 patent/WO2015107502A1/en active Application Filing
- 2015-01-19 US US15/032,823 patent/US20160317705A1/en not_active Abandoned
- 2015-01-19 ES ES15707784T patent/ES2771856T3/es active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2015107502A1 (en) | 2015-07-23 |
| EP3096804A1 (en) | 2016-11-30 |
| EP3096804B1 (en) | 2019-12-04 |
| ES2771856T3 (es) | 2020-07-07 |
| RU2016133447A (ru) | 2018-03-02 |
| US20160317705A1 (en) | 2016-11-03 |
| CN105934258A (zh) | 2016-09-07 |
| RU2016133447A3 (es) | 2018-08-06 |
| PT3096804T (pt) | 2020-02-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |