MX2016003372A - Composiciones para el tratamiento de la hipertension y/o la fibrosis. - Google Patents

Composiciones para el tratamiento de la hipertension y/o la fibrosis.

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Publication number
MX2016003372A
MX2016003372A MX2016003372A MX2016003372A MX2016003372A MX 2016003372 A MX2016003372 A MX 2016003372A MX 2016003372 A MX2016003372 A MX 2016003372A MX 2016003372 A MX2016003372 A MX 2016003372A MX 2016003372 A MX2016003372 A MX 2016003372A
Authority
MX
Mexico
Prior art keywords
fibrosis
hypertension
treatment
compositions
prophylactic
Prior art date
Application number
MX2016003372A
Other languages
English (en)
Other versions
MX368011B (es
Inventor
Annette Duggan Karen
Original Assignee
Vectus Biosystems Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2013903572A external-priority patent/AU2013903572A0/en
Application filed by Vectus Biosystems Ltd filed Critical Vectus Biosystems Ltd
Publication of MX2016003372A publication Critical patent/MX2016003372A/es
Publication of MX368011B publication Critical patent/MX368011B/es

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    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
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    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
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    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
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    • C07C233/07—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
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Abstract

La presente invención se refiere a compuestos novedosos y a su uso en el tratamiento profiláctico y/o terapéutico de la hipertensión y/o la fibrosis.
MX2016003372A 2013-09-17 2014-09-17 Composiciones para el tratamiento de la hipertensión y/o la fibrosis. MX368011B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2013903572A AU2013903572A0 (en) 2013-09-17 Compositions for the treatment of hypertension and/or fibrosis
AU2013903571A AU2013903571A0 (en) 2013-09-17 Compositions for the treatment of hypertension and/or fibrosis
PCT/AU2014/000922 WO2015039172A1 (en) 2013-09-17 2014-09-17 Compositions for the treatment of hypertension and/or fibrosis

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MX2016003372A true MX2016003372A (es) 2016-10-21
MX368011B MX368011B (es) 2019-09-13

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EP (1) EP3046902B1 (es)
JP (1) JP6293266B2 (es)
KR (1) KR101863708B1 (es)
CN (1) CN105683153B (es)
AP (1) AP2016009080A0 (es)
AU (1) AU2014324075B2 (es)
BR (1) BR112016005606B1 (es)
CA (1) CA2924353C (es)
DK (1) DK3046902T3 (es)
ES (1) ES2694375T3 (es)
IL (1) IL244622A0 (es)
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MY (1) MY191337A (es)
NZ (1) NZ717930A (es)
PH (1) PH12016500495B1 (es)
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BR112016005601B1 (pt) * 2013-09-17 2021-02-02 Vectus Biosystems Limited composto, composição farmacêutica, e usos de um composto
ES2766769T3 (es) * 2015-03-18 2020-06-15 Vectus Biosystems Ltd Composiciones para el tratamiento de la fibrosis y de las afecciones relacionadas con la fibrosis
KR102554476B1 (ko) * 2015-03-18 2023-07-10 벡투스 바이오시스템즈 리미티드 신장 및／또는 간 질환 치료용 조성물
EP3490970B1 (en) * 2016-07-28 2023-09-13 Vectus Biosystems Limited Compositions for the treatment of pulmonary fibrosis
CN108779115B (zh) 2016-10-14 2021-02-26 江苏恒瑞医药股份有限公司 五元杂芳环并桥环类衍生物、其制备方法及其在医药上的应用
US11447488B2 (en) 2017-10-06 2022-09-20 Takeda Pharmaceutical Company Limited Heterocyclic compounds
BR112022023559A2 (pt) * 2020-05-21 2023-01-24 Stemsynergy Therapeutics Inc Inibidores de notch e seus usos

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JP2004520386A (ja) * 2001-01-31 2004-07-08 ファイザー・プロダクツ・インク Ｐｄｅ４アイソザイムの阻害剤として有用なニコチンアミドビアリール誘導体
IL160917A0 (en) * 2001-10-18 2004-08-31 Bristol Myers Squibb Co Human glucagon-like-peptide-1 mimics and their use in the treatment of diabetes and related conditions
US20030162824A1 (en) * 2001-11-12 2003-08-28 Krul Elaine S. Methods of treating or preventing a cardiovascular condition using a cyclooxygenase-1 inhibitor
AU2003243870B2 (en) 2002-06-25 2008-11-20 Merck Frosst Canada Ltd 8-(biaryl) quinoline PDE4 inhibitors
SE0301010D0 (sv) * 2003-04-07 2003-04-07 Astrazeneca Ab Novel compounds
WO2005120545A1 (en) * 2004-06-11 2005-12-22 Vectus Biosystems Limited Compositions and methods for treatment of cardiovascular disease
MX2007001943A (es) * 2004-08-17 2007-05-09 Galderma Res & Dev Nuevos compuestos biaromaticos activadores de los receptores del tipo receptor activado del proliferador de peroxisoma (ppar) y su uso en composiciones cosmeticas o farmaceuticas.
TW200831080A (en) * 2006-12-15 2008-08-01 Irm Llc Compounds and compositions as inhibitors of cannabinoid receptor 1 activity
US20100179203A1 (en) * 2007-07-04 2010-07-15 Antonio Nardi Novel pyrazole derivatives useful as potassium channel modulators
TW201021797A (en) * 2008-12-04 2010-06-16 Nat Univ Tsing Hua 1,2,3-triazole derivatives as new cannabinoid-1 receptor antagonists
EP2396301A2 (en) * 2009-02-13 2011-12-21 Jerini AG Small molecule bradykinin b1 receptor antagonists
KR101442897B1 (ko) * 2009-05-28 2014-09-23 노파르티스 아게 네프릴리신 억제제로서의 치환된 아미노프로피온산 유도체
US20120088737A2 (en) * 2009-10-02 2012-04-12 Ajinomoto Co., Inc Novel acyl guanidine derivatives

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EP3046902A4 (en) 2017-01-25
KR101863708B1 (ko) 2018-06-01
WO2015039172A1 (en) 2015-03-26
US20160280671A1 (en) 2016-09-29
IL244622A0 (en) 2016-04-21
CA2924353A1 (en) 2015-03-26
NZ717930A (en) 2018-12-21
MY191337A (en) 2022-06-16
PH12016500495A1 (en) 2016-05-23
ES2694375T3 (es) 2018-12-20
SG11201601641VA (en) 2016-04-28
UA117254C2 (uk) 2018-07-10
JP2016531846A (ja) 2016-10-13
BR112016005606B1 (pt) 2020-09-15
MX368011B (es) 2019-09-13
DK3046902T3 (en) 2018-12-03
CA2924353C (en) 2018-12-04
AU2014324075B2 (en) 2017-03-02
RU2016112053A (ru) 2017-10-23
PH12016500495B1 (en) 2016-05-23
AU2014324075A1 (en) 2016-04-07
KR20160071384A (ko) 2016-06-21
US9630935B2 (en) 2017-04-25
CN105683153A (zh) 2016-06-15
AP2016009080A0 (en) 2016-03-31
EP3046902B1 (en) 2018-08-08
EP3046902A1 (en) 2016-07-27
JP6293266B2 (ja) 2018-03-14
RU2661878C2 (ru) 2018-07-20
CN105683153B (zh) 2018-07-13

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