MX2015006871A - Proceso de cristalizacion de derivados de indoles triciclicos. - Google Patents
Proceso de cristalizacion de derivados de indoles triciclicos.Info
- Publication number
- MX2015006871A MX2015006871A MX2015006871A MX2015006871A MX2015006871A MX 2015006871 A MX2015006871 A MX 2015006871A MX 2015006871 A MX2015006871 A MX 2015006871A MX 2015006871 A MX2015006871 A MX 2015006871A MX 2015006871 A MX2015006871 A MX 2015006871A
- Authority
- MX
- Mexico
- Prior art keywords
- composition
- tricyclic indole
- crystallization process
- indole derivatives
- tricyclic
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 229940054051 antipsychotic indole derivative Drugs 0.000 title 1
- 238000002425 crystallisation Methods 0.000 title 1
- 230000008025 crystallization Effects 0.000 title 1
- 150000002475 indoles Chemical class 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 6
- SIKJAQJRHWYJAI-UHFFFAOYSA-N benzopyrrole Natural products C1=CC=C2NC=CC2=C1 SIKJAQJRHWYJAI-UHFFFAOYSA-N 0.000 abstract 2
- PZOUSPYUWWUPPK-UHFFFAOYSA-N indole Natural products CC1=CC=CC2=C1C=CN2 PZOUSPYUWWUPPK-UHFFFAOYSA-N 0.000 abstract 2
- -1 indole compound Chemical class 0.000 abstract 2
- RKJUIXBNRJVNHR-UHFFFAOYSA-N indolenine Natural products C1=CC=C2CC=NC2=C1 RKJUIXBNRJVNHR-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000032 diagnostic agent Substances 0.000 abstract 1
- 229940039227 diagnostic agent Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000012535 impurity Substances 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 238000000968 medical method and process Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
- C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Rheumatology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN3689DE2012 | 2012-11-30 | ||
| GBGB1300647.3A GB201300647D0 (en) | 2013-01-15 | 2013-01-15 | Crystallization |
| PCT/EP2013/074986 WO2014083113A1 (en) | 2012-11-30 | 2013-11-28 | Crystallization process of tricyclic indole derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2015006871A true MX2015006871A (es) | 2015-09-16 |
Family
ID=54266915
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2015006871A MX2015006871A (es) | 2012-11-30 | 2013-11-28 | Proceso de cristalizacion de derivados de indoles triciclicos. |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US10709798B2 (enExample) |
| EP (1) | EP2943195A1 (enExample) |
| JP (1) | JP6280560B2 (enExample) |
| KR (1) | KR20150088802A (enExample) |
| CN (2) | CN104837489A (enExample) |
| AU (1) | AU2013351152A1 (enExample) |
| BR (1) | BR112015012138A2 (enExample) |
| CA (1) | CA2892485A1 (enExample) |
| IN (1) | IN2015DN03978A (enExample) |
| MX (1) | MX2015006871A (enExample) |
| RU (1) | RU2015118217A (enExample) |
| WO (1) | WO2014083113A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2015118217A (ru) | 2012-11-30 | 2017-01-11 | ДжиИ ХЕЛТКЕР ЛИМИТЕД | Способ кристаллизации трициклических индольных производных |
| US20160144477A1 (en) * | 2014-11-21 | 2016-05-26 | Diane Scott | Coated compressive subpad for chemical mechanical polishing |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6177440B1 (en) * | 1996-10-30 | 2001-01-23 | Eli Lilly And Company | Substituted tricyclics |
| CA2310250A1 (en) | 1997-11-14 | 1999-05-27 | August Masaru Watanabe | Treatment for alzheimer's disease |
| DZ2769A1 (fr) | 1998-04-17 | 2003-12-01 | Lilly Co Eli | Composés tricycliques substitués. |
| JP2005527466A (ja) | 2001-08-09 | 2005-09-15 | イーライ・リリー・アンド・カンパニー | ｓＰＬＡ２インヒビターとしてのシクロヘプトＢインドール誘導体 |
| WO2003014082A1 (en) | 2001-08-09 | 2003-02-20 | Eli Lilly And Company | Cyclopenta ` b ! indole derivatives as spla2 inhibitors |
| GB0905328D0 (en) * | 2009-03-27 | 2009-05-13 | Ge Healthcare Ltd | Indole derivatives |
| SG183837A1 (en) * | 2010-03-26 | 2012-10-30 | Ge Healthcare Ltd | Tricyclic indole derivatives as pbr ligands |
| GB201016038D0 (en) | 2010-09-24 | 2010-11-10 | Ge Healthcare Ltd | In vivo imaging method |
| GB201016411D0 (en) * | 2010-09-30 | 2010-11-10 | Ge Healthcare Ltd | In vivo imaging method for cancer |
| GB201021263D0 (en) | 2010-12-15 | 2011-01-26 | Ge Healthcare Ltd | Solid phase extraction method |
| US9220795B2 (en) * | 2011-09-22 | 2015-12-29 | Ge Healthcare Limited | Indole derivatives |
| RU2015118217A (ru) | 2012-11-30 | 2017-01-11 | ДжиИ ХЕЛТКЕР ЛИМИТЕД | Способ кристаллизации трициклических индольных производных |
-
2013
- 2013-11-28 RU RU2015118217A patent/RU2015118217A/ru not_active Application Discontinuation
- 2013-11-28 CN CN201380062872.4A patent/CN104837489A/zh active Pending
- 2013-11-28 MX MX2015006871A patent/MX2015006871A/es unknown
- 2013-11-28 IN IN3978DEN2015 patent/IN2015DN03978A/en unknown
- 2013-11-28 CA CA2892485A patent/CA2892485A1/en not_active Abandoned
- 2013-11-28 US US14/648,353 patent/US10709798B2/en active Active
- 2013-11-28 WO PCT/EP2013/074986 patent/WO2014083113A1/en not_active Ceased
- 2013-11-28 KR KR1020157013974A patent/KR20150088802A/ko not_active Withdrawn
- 2013-11-28 BR BR112015012138A patent/BR112015012138A2/pt not_active IP Right Cessation
- 2013-11-28 JP JP2015544462A patent/JP6280560B2/ja active Active
- 2013-11-28 CN CN202010090283.9A patent/CN111362863A/zh active Pending
- 2013-11-28 AU AU2013351152A patent/AU2013351152A1/en not_active Abandoned
- 2013-11-28 EP EP13796090.2A patent/EP2943195A1/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| BR112015012138A2 (pt) | 2017-07-11 |
| WO2014083113A1 (en) | 2014-06-05 |
| KR20150088802A (ko) | 2015-08-03 |
| EP2943195A1 (en) | 2015-11-18 |
| RU2015118217A (ru) | 2017-01-11 |
| CN111362863A (zh) | 2020-07-03 |
| AU2013351152A1 (en) | 2015-05-21 |
| CA2892485A1 (en) | 2014-06-05 |
| US20150335766A1 (en) | 2015-11-26 |
| CN104837489A (zh) | 2015-08-12 |
| US10709798B2 (en) | 2020-07-14 |
| IN2015DN03978A (enExample) | 2015-10-02 |
| JP2016507477A (ja) | 2016-03-10 |
| JP6280560B2 (ja) | 2018-02-14 |
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