MX2014013521A - Sistema monolitico a base de quitosan con microagujas para aplicacion transdermica. - Google Patents

Sistema monolitico a base de quitosan con microagujas para aplicacion transdermica.

Info

Publication number
MX2014013521A
MX2014013521A MX2014013521A MX2014013521A MX2014013521A MX 2014013521 A MX2014013521 A MX 2014013521A MX 2014013521 A MX2014013521 A MX 2014013521A MX 2014013521 A MX2014013521 A MX 2014013521A MX 2014013521 A MX2014013521 A MX 2014013521A
Authority
MX
Mexico
Prior art keywords
micro
needles
chitosan
skin
needle
Prior art date
Application number
MX2014013521A
Other languages
English (en)
Inventor
Flora Adriana Ganem Rondero
Marco Antonio Espinosa Olivares
Original Assignee
Univ Nac Autónoma De México
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Nac Autónoma De México filed Critical Univ Nac Autónoma De México
Priority to MX2014013521A priority Critical patent/MX2014013521A/es
Publication of MX2014013521A publication Critical patent/MX2014013521A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0216—Solid or semisolid forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/736—Chitin; Chitosan; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/91—Injection

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Media Introduction/Drainage Providing Device (AREA)

Abstract

Se describe un sistema de microagujas, así como el método de manufactura para producirlo. El sistema con microagujas está formado enteramente de quitosán. El quitosán es un material biodegradable y biocompatible, capaz de hinchar y disolverse en la piel. El método de manufactura consiste en la fabricación de un molde con ayuda de agujas de acupuntura. Es posible ajustar la longitud de las microagujas fijando la posición de las agujas de acupuntura. El llenado del molde con una solución de quitosán se logra por centrifugación. Como ejemplo, se prepararon microagujas con longitudes entre 200 and 500 µm. Las microagujas de quitosán obtenidas por el método propuesto mostraron tener la resistencia mecánica requerida para insertarse en la piel. Agentes farmacéuticos y/o cosméticos pueden ser incluidos en la estructura de las microagujas o bien pueden recubrir su superficie, de modo que al insertarse en la piel, liberen su contenido.
MX2014013521A 2014-11-06 2014-11-06 Sistema monolitico a base de quitosan con microagujas para aplicacion transdermica. MX2014013521A (es)

Priority Applications (1)

Application Number Priority Date Filing Date Title
MX2014013521A MX2014013521A (es) 2014-11-06 2014-11-06 Sistema monolitico a base de quitosan con microagujas para aplicacion transdermica.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
MX2014013521A MX2014013521A (es) 2014-11-06 2014-11-06 Sistema monolitico a base de quitosan con microagujas para aplicacion transdermica.

Publications (1)

Publication Number Publication Date
MX2014013521A true MX2014013521A (es) 2016-05-06

Family

ID=56797782

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014013521A MX2014013521A (es) 2014-11-06 2014-11-06 Sistema monolitico a base de quitosan con microagujas para aplicacion transdermica.

Country Status (1)

Country Link
MX (1) MX2014013521A (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11517729B2 (en) 2018-08-20 2022-12-06 University Of Washington Integrated fiber microneedle device for drug and vaccine delivery

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11517729B2 (en) 2018-08-20 2022-12-06 University Of Washington Integrated fiber microneedle device for drug and vaccine delivery

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Legal Events

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FG Grant or registration