MX2014011186A - Metodo para mejorar la eficiencia de las transfusiones de sangre. - Google Patents

Metodo para mejorar la eficiencia de las transfusiones de sangre.

Info

Publication number
MX2014011186A
MX2014011186A MX2014011186A MX2014011186A MX2014011186A MX 2014011186 A MX2014011186 A MX 2014011186A MX 2014011186 A MX2014011186 A MX 2014011186A MX 2014011186 A MX2014011186 A MX 2014011186A MX 2014011186 A MX2014011186 A MX 2014011186A
Authority
MX
Mexico
Prior art keywords
blood transfusions
enhancing efficacy
efficacy
blood
subject
Prior art date
Application number
MX2014011186A
Other languages
English (en)
Spanish (es)
Inventor
Seetharama A Acharya
Marcos Intaglietta
Original Assignee
Einstein Coll Med
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Einstein Coll Med filed Critical Einstein Coll Med
Publication of MX2014011186A publication Critical patent/MX2014011186A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/38Albumins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/18Erythrocytes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/38Albumins
    • A61K38/385Serum albumin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/41Porphyrin- or corrin-ring-containing peptides
    • A61K38/42Haemoglobins; Myoglobins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76Albumins
    • C07K14/765Serum albumin, e.g. HSA
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/795Porphyrin- or corrin-ring-containing peptides
    • C07K14/805Haemoglobins; Myoglobins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
MX2014011186A 2012-03-20 2013-03-12 Metodo para mejorar la eficiencia de las transfusiones de sangre. MX2014011186A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261613105P 2012-03-20 2012-03-20
PCT/US2013/030355 WO2013142135A1 (en) 2012-03-20 2013-03-12 Method of enhancing efficacy of blood transfusions

Publications (1)

Publication Number Publication Date
MX2014011186A true MX2014011186A (es) 2015-03-06

Family

ID=49223191

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014011186A MX2014011186A (es) 2012-03-20 2013-03-12 Metodo para mejorar la eficiencia de las transfusiones de sangre.

Country Status (10)

Country Link
US (2) US8859499B2 (en:Method)
EP (1) EP2827887A4 (en:Method)
JP (1) JP2015515462A (en:Method)
BR (1) BR112014023200A2 (en:Method)
CL (1) CL2014002464A1 (en:Method)
HK (1) HK1204267A1 (en:Method)
IN (1) IN2014MN02089A (en:Method)
MX (1) MX2014011186A (en:Method)
WO (1) WO2013142135A1 (en:Method)
ZA (1) ZA201407616B (en:Method)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10626399B2 (en) 2010-01-28 2020-04-21 The Board Of Trustees Of The Leland Stanford Junior University Methods of treating cognitive symptoms of an aging-associated impairment by modulating C-C chemokine receptor type 3 (CCR3)
US20160208011A1 (en) 2010-01-28 2016-07-21 The Board Of Trustees Of The Leland Stanford Junior University Ccr3 modulation in the treatment of aging-associated impairments, and compositions for practicing the same
US10487148B2 (en) 2010-01-28 2019-11-26 The Board Of Trustees Of The Leland Stanford Junior University Methods and compositions for treating aging-associated impairments
US9161968B2 (en) 2011-04-08 2015-10-20 The Board Of Trustees Of The Leland Stanford Junior University Methods of neuroprotection involving macrophage colony stimulating factor receptor agonists
US8859499B2 (en) 2012-03-20 2014-10-14 Albert Einstein College Of Medicine Of Yeshiva University Method of enhancing efficacy of blood transfusions
US10905779B2 (en) 2013-12-09 2021-02-02 The Board Of Trustees Of The Leland Stanford Junior University Methods for screening human blood products comprising plasma using immunocompromised rodent models
EA035336B1 (ru) * 2013-12-09 2020-05-29 Зе Боард Оф Трастиз Оф Зе Леланд Стэнфорд Джуниор Юниверсити Способ лечения связанного со старением когнитивного расстройства или заболевания
WO2016077825A1 (en) * 2014-11-14 2016-05-19 Aima Biotech Conjugated proteins
EP3229843B1 (en) 2014-11-25 2020-01-01 Curadigm Sas Pharmaceutical composition, preparation and uses thereof
EP3096160B1 (en) * 2015-05-20 2020-02-26 Veoneer Sweden AB An fmcw vehicle radar system
MX2017015424A (es) 2015-05-28 2018-03-01 Nanobiotix Nanoparticulas para su uso como vacuna terapeutica.
PT3307296T (pt) 2015-06-15 2022-01-07 Univ Leland Stanford Junior Timp2 para uso no tratamento de condições associadas ao envelhecimento
US11065277B2 (en) * 2015-11-09 2021-07-20 Albert Einstein College Of Medicine Method of ameliorating side effects of sickle cell disease treatments
WO2017103914A1 (en) * 2015-12-17 2017-06-22 Regentis Biomaterials Ltd. Ready for use organic solvent free compositions comprising protein-polymer conjugates and uses thereof
WO2017189919A2 (en) 2016-04-28 2017-11-02 Alkahest, Inc. Blood plasma and plasma fractions as therapy for tumor growth and progression
EA039316B1 (ru) 2016-10-24 2022-01-12 Алкахест, Инк. Фракции плазмы крови в качестве лечения когнитивных расстройств, связанных со старением
US11040068B2 (en) 2017-04-26 2021-06-22 Alkahest, Inc. Dosing regimen for treatment of cognitive and motor impairments with blood plasma and blood plasma products
KR20190135059A (ko) 2017-04-26 2019-12-05 알카헤스트 인코포레이티드 혈장 및 혈장 산물로 인지 및 운동 장애를 치료하기 위한 투여 요법
WO2019018403A1 (en) 2017-07-18 2019-01-24 Virtech Bio, Llc BLOOD SUBSTITUTES COMPRISING HEMOGLOBIN AND METHODS OF MAKING
UA128648C2 (uk) 2018-10-26 2024-09-18 Алкахест, Інк. Застосування плазми крові та фракцій плазми для пом'якшення болю, поліпшення загоювання ран та післяопераційного відновлення
JP7773169B2 (ja) * 2021-02-24 2025-11-19 学校法人 中央大学 ポリオキサゾリン結合アルブミン、人工血漿増量剤及び出血ショックの蘇生液

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4267269A (en) * 1980-02-05 1981-05-12 Baxter Travenol Laboratories, Inc. Red cell storage solution
JPS56139419A (en) * 1980-03-31 1981-10-30 Kuraray Co Ltd Erythrocytic preservative and erythrocytic pharmaceutical for preservation
AU752037B2 (en) * 1997-09-26 2002-09-05 Uab Research Foundation Reduced antigenic cells and uses therefor
ATE256474T1 (de) * 1998-09-25 2004-01-15 Oklahoma Med Res Found Hemmung der sichelbildung von erythrozyten mittels n-l-alpha-aspartyl-l-phenylalanine 1- methylester
US6251927B1 (en) * 1999-04-20 2001-06-26 Medinox, Inc. Methods for treatment of sickle cell anemia
US6875423B1 (en) * 1999-09-21 2005-04-05 Marcos Intaglietta Methods for increasing peripheral blood circulation
US6670323B1 (en) * 1999-11-12 2003-12-30 Baxter International, Inc. Reduced side-effect hemoglobin compositions
US6811778B2 (en) * 2001-09-10 2004-11-02 Biopure Corporation Method for improving oxygen transport by stored red blood cells
US20080194481A1 (en) * 2001-12-21 2008-08-14 Human Genome Sciences, Inc. Albumin Fusion Proteins
US7144989B2 (en) * 2002-03-25 2006-12-05 Albert Einstein College Of Medicine Of Yeshiva University Pegylated non-hypertensive hemoglobins, methods of preparing same, and uses thereof
US7521174B2 (en) * 2003-12-05 2009-04-21 Albert Einstein College Of Medicine Of Yeshiva University Universal red blood cells, methods of preparing same, and uses thereof
CN101098698A (zh) * 2004-12-01 2008-01-02 德福根有限公司 与离子通道尤其是Kv家族离子通道相互作用的5-羧酰胺基取代的噻唑衍生物
US8071546B2 (en) * 2005-06-10 2011-12-06 La Jolla Bioengineering Institute Uses of pegylated albumin
WO2006135740A1 (en) * 2005-06-10 2006-12-21 Albert Einstein College Of Medicine Of Yeshiva University Pegylated hemoglobin and albumin and uses thereof
WO2010087986A2 (en) * 2009-01-30 2010-08-05 Simpkins Cuthbert O Resuscitation fluid
WO2010117423A2 (en) * 2009-03-31 2010-10-14 Duke University A METHOD FOR TREATING A PATIENT HAVING OR AT RISK FOR DEVELOPING A DISORDER ASSOCIATED WITH DECREASED EXPRESSION OF ß2 ADRENERGIC RECEPTORS OR NEED FOR INCREASED ß2 ADRENERGIC RECEPTOR ACTIVITY
LT2440239T (lt) * 2009-06-09 2017-12-11 Prolong Pharmaceuticals, LLC Hemoglobino kompozicijos
US20110189166A1 (en) * 2010-01-29 2011-08-04 John Boucher Methods of treating hemorheologic abnormalities in mammals
WO2011106086A1 (en) * 2010-02-25 2011-09-01 Albert Einstein College Of Medicine Of Yeshiva University Pegylated albumin polymers and uses thereof
US8859499B2 (en) 2012-03-20 2014-10-14 Albert Einstein College Of Medicine Of Yeshiva University Method of enhancing efficacy of blood transfusions
WO2016077825A1 (en) 2014-11-14 2016-05-19 Aima Biotech Conjugated proteins

Also Published As

Publication number Publication date
ZA201407616B (en) 2016-08-31
US8859499B2 (en) 2014-10-14
HK1204267A1 (en) 2015-11-13
EP2827887A4 (en) 2016-04-20
JP2015515462A (ja) 2015-05-28
US20150017146A1 (en) 2015-01-15
WO2013142135A1 (en) 2013-09-26
EP2827887A1 (en) 2015-01-28
US20130261061A1 (en) 2013-10-03
IN2014MN02089A (en:Method) 2015-09-11
CL2014002464A1 (es) 2015-08-28
US9498537B2 (en) 2016-11-22
BR112014023200A2 (pt) 2018-09-18

Similar Documents

Publication Publication Date Title
MX2014011186A (es) Metodo para mejorar la eficiencia de las transfusiones de sangre.
MX2019003525A (es) Moduladores alostericos de proteina nucleo de hepatitis b.
PH12018500572A1 (en) Hepatitis b core protein modulators
PH12014501702A1 (en) Imidazopyrrolidinone compounds
WO2012149299A3 (en) Methods for the treatment of cancer and inflammatory diseases using cereblon as a predictor
NZ716473A (en) Diagnosis and therapy of cancer involving cancer stem cells
PH12015500954A1 (en) Device for extracorporeal blood treatment
HK1204578A1 (en) Medicament for the treatment of acute myeloid leukemia (aml)
MX373851B (es) Métodos de administración de tratamiento con pirfenidona.
WO2014160281A3 (en) Method of enhancing delivery of therapeutic compounds to the eye
MX364220B (es) Metodos de tratamientos de fibrosis.
GB201207543D0 (en) Treatment of transfusion blood
EA201500370A1 (ru) ФАРМАЦЕВТИЧЕСКИЕ КОМБИНАЦИИ, СОДЕРЖАЩИЕ ДВОЙНЫЕ АНГИОПОЭТИН-2/Dll4 СВЯЗЫВАЮЩИЕ АГЕНТЫ И АНТИ-VEGF-R АГЕНТЫ
MX362111B (es) Un metodo para mejorar la funcion hepatica.
WO2013090319A3 (en) Treatment of type i and type ii diabetes
EA201492161A1 (ru) N-метил-4-бензилкарбамидопиридиний хлорид и способ его получения
HK1220133A1 (zh) 改善微血管完整性的方法
UA103141C2 (ru) Применение анти-hsp60 антител в качестве маркеров иммунной безопасности проведения гемотрансфузий в кардиохирургии врожденных пороков сердца
UA97741C2 (ru) Способ восстановления кожных покровов при глубоких распространенных ожогах микроаутодермотрансплантатами
UA79303U (ru) Применение таурина как средства стабилизации концентрации итраконазола в плазме крови при лечении грибковых заболеваний
UA97054C2 (ru) Способ комплексного лечения больных с зависимостью вследствие употребления психоактивных веществ
RU2012149676A (ru) Способ лечения телят, больных симулиидотоксикозом
UA71871U (ru) Способ диагностики эффективности антибиотикотерапии у больных лайм-борелиозом