MX2013013243A - Means and methods for active cellular immunotherapy of cancer by using tumor cells killed by high hydrostatic pressure and dendritic cells. - Google Patents

Means and methods for active cellular immunotherapy of cancer by using tumor cells killed by high hydrostatic pressure and dendritic cells.

Info

Publication number
MX2013013243A
MX2013013243A MX2013013243A MX2013013243A MX2013013243A MX 2013013243 A MX2013013243 A MX 2013013243A MX 2013013243 A MX2013013243 A MX 2013013243A MX 2013013243 A MX2013013243 A MX 2013013243A MX 2013013243 A MX2013013243 A MX 2013013243A
Authority
MX
Mexico
Prior art keywords
methods
hydrostatic pressure
cancer
tumor cells
high hydrostatic
Prior art date
Application number
MX2013013243A
Other languages
Spanish (es)
Inventor
Jirina Bartunková
Radek Spísek
Original Assignee
Sotio As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP11172622A external-priority patent/EP2543386A1/en
Application filed by Sotio As filed Critical Sotio As
Publication of MX2013013243A publication Critical patent/MX2013013243A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0639Dendritic cells, e.g. Langherhans cells in the epidermis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515Animal cells
    • A61K2039/5152Tumor cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515Animal cells
    • A61K2039/5154Antigen presenting cells [APCs], e.g. dendritic cells or macrophages

Abstract

Disclosed are pharmaceutical compositions for inducing an immune response against tumor cells comprising tumor cells which are made apoptotic by treatment with high hydrostatic pressure and dendritic cells, and methods for producing such compositions.
MX2013013243A 2011-07-05 2012-07-04 Means and methods for active cellular immunotherapy of cancer by using tumor cells killed by high hydrostatic pressure and dendritic cells. MX2013013243A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161504387P 2011-07-05 2011-07-05
EP11172622A EP2543386A1 (en) 2011-07-05 2011-07-05 Means and methods for active cellular immunotherapy of cancer by using tumor cells killed by high hydrostatic pressure
PCT/EP2012/062950 WO2013004708A1 (en) 2011-07-05 2012-07-04 Means and methods for active cellular immunotherapy of cancer by using tumor cells killed by high hydrostatic pressure and dendritic cells

Publications (1)

Publication Number Publication Date
MX2013013243A true MX2013013243A (en) 2014-05-30

Family

ID=50023029

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013013243A MX2013013243A (en) 2011-07-05 2012-07-04 Means and methods for active cellular immunotherapy of cancer by using tumor cells killed by high hydrostatic pressure and dendritic cells.

Country Status (7)

Country Link
JP (1) JP6235085B2 (en)
CL (1) CL2013003282A1 (en)
CY (1) CY1115803T1 (en)
HR (1) HRP20141230T1 (en)
IL (2) IL229702A (en)
MX (1) MX2013013243A (en)
ZA (1) ZA201307886B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112014009346B1 (en) 2011-10-17 2020-09-15 Massachusetts Institute Of Technology INTRACELLULAR DELIVERY
US10124336B2 (en) 2013-08-16 2018-11-13 Massachusetts Institute Of Technology Selective delivery of material to cells
JP2017533702A (en) 2014-10-31 2017-11-16 マサチューセッツ インスティテュート オブ テクノロジー Delivery of biomolecules to immune cells
EP3218492A4 (en) 2014-11-14 2018-10-10 Massachusetts Institute Of Technology Disruption and field enabled delivery of compounds and compositions into cells
CN107250373A (en) 2015-01-12 2017-10-13 麻省理工学院 The gene editing realized is delivered by microfluid
CA2988996A1 (en) 2015-07-09 2017-01-12 Massachusetts Institute Of Technology Delivery of materials to anucleate cells

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002504322A (en) * 1998-02-20 2002-02-12 ザ ロックフェラー ユニバーシティー Apoptotic cell-mediated antigen presentation to dendritic cells
US8420078B2 (en) * 2005-03-10 2013-04-16 Yeda Research And Development Co. Ltd. Methods and immunogenic cell preparations for treating antigen-associated diseases

Also Published As

Publication number Publication date
CY1115803T1 (en) 2017-01-25
IL247781A0 (en) 2016-11-30
IL247781B (en) 2019-11-28
IL229702A (en) 2016-09-29
IL229702A0 (en) 2014-01-30
ZA201307886B (en) 2015-03-25
HRP20141230T1 (en) 2015-02-13
CL2013003282A1 (en) 2014-10-10
JP2017025066A (en) 2017-02-02
JP6235085B2 (en) 2017-11-22

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