MX2010001491A - Proteina precursora de tiopeptidos, gen que la codifica, y usos de la misma. - Google Patents

Proteina precursora de tiopeptidos, gen que la codifica, y usos de la misma.

Info

Publication number
MX2010001491A
MX2010001491A MX2010001491A MX2010001491A MX2010001491A MX 2010001491 A MX2010001491 A MX 2010001491A MX 2010001491 A MX2010001491 A MX 2010001491A MX 2010001491 A MX2010001491 A MX 2010001491A MX 2010001491 A MX2010001491 A MX 2010001491A
Authority
MX
Mexico
Prior art keywords
thiopeptide
precursor protein
gene encoding
present
relates
Prior art date
Application number
MX2010001491A
Other languages
English (en)
Inventor
Rowan Morris
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MX2010001491A publication Critical patent/MX2010001491A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/36—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Actinomyces; from Streptomyces (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

La presente invención se refiere a las proteínas precursoras para la biosíntesis de tiopéptidos, y a los genes estructurales correspondientes, y a los usos de las mismas. La presente invención también se refiere a métodos para manipular genéticamente la proteína precursora de tiopéptidos o las células huésped que expresan un gen que codifica esta proteína precursora de tiopéptidos, para producir compuestos de tiopéptidos o sus derivados. La presente invención se refiere además a la donación y caracterización de los genes involucrados en la biosíntesis de tiopéptidos, y a su uso en la producción de compuestos de tiopéptidos.
MX2010001491A 2007-08-09 2008-08-06 Proteina precursora de tiopeptidos, gen que la codifica, y usos de la misma. MX2010001491A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07114121 2007-08-09
PCT/EP2008/060339 WO2009019289A1 (en) 2007-08-09 2008-08-06 Thiopeptide precursor protein, gene encoding it and uses thereof

Publications (1)

Publication Number Publication Date
MX2010001491A true MX2010001491A (es) 2010-03-01

Family

ID=38543755

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010001491A MX2010001491A (es) 2007-08-09 2008-08-06 Proteina precursora de tiopeptidos, gen que la codifica, y usos de la misma.

Country Status (11)

Country Link
US (1) US20110183374A1 (es)
EP (2) EP2647647A3 (es)
JP (1) JP2010535481A (es)
KR (1) KR20100049580A (es)
CN (2) CN103483424A (es)
AU (1) AU2008285655B2 (es)
BR (1) BRPI0815371A2 (es)
CA (1) CA2695813A1 (es)
EA (1) EA201000273A1 (es)
MX (1) MX2010001491A (es)
WO (1) WO2009019289A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101586112B (zh) * 2009-06-19 2011-06-22 中国科学院上海有机化学研究所 诺丝七肽的生物合成基因簇
CN101684471A (zh) * 2009-07-24 2010-03-31 中国科学院上海有机化学研究所 诺卡噻唑菌素的生物合成基因簇
WO2014167371A1 (en) 2013-04-12 2014-10-16 Naicons S.C.A.R.L. Analogs of the antibiotic aminothiazole ge2270
MX2016003255A (es) * 2013-09-13 2016-06-07 Reg Life Sciences Llc Variantes mejoradas de acetil-coa carboxilasa.
EP3111949A1 (en) * 2015-07-01 2017-01-04 Deinobiotics New bicyclic lipopeptide, preparation and use as antimicrobial agent
CN106319004B (zh) * 2015-07-09 2020-10-27 牡丹江佰佳信生物科技有限公司 一种可提高那西肽产量的发酵培养基及培养方法
CN107641146B (zh) * 2016-07-21 2022-10-04 中国科学院上海有机化学研究所 高产盐屋霉素及其类似物的产生菌、盐屋霉素及其类似物的制法及其用途
CN106366168B (zh) * 2016-08-26 2020-09-15 上海交通大学 羊毛硫肽类抗菌肽及其脱氢衍生物的制备方法
CN114561406A (zh) * 2022-04-26 2022-05-31 北京工商大学 一种参与阳离子肽化合物合成的基因及其用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5639949A (en) * 1990-08-20 1997-06-17 Ciba-Geigy Corporation Genes for the synthesis of antipathogenic substances
US6485972B1 (en) * 1998-10-15 2002-11-26 President And Fellows Of Harvard College WNT signalling in reproductive organs
WO2001064835A2 (en) * 2000-02-28 2001-09-07 Hyseq, Inc. Novel nucleic acids and polypeptides
WO2001057252A2 (en) * 2000-02-04 2001-08-09 Aeomica, Inc. Methods and apparatus for high-throughput detection and characterization of alternatively spliced genes
US6436703B1 (en) * 2000-03-31 2002-08-20 Hyseq, Inc. Nucleic acids and polypeptides

Also Published As

Publication number Publication date
KR20100049580A (ko) 2010-05-12
EA201000273A1 (ru) 2010-10-29
EP2647647A3 (en) 2014-10-01
AU2008285655A1 (en) 2009-02-12
US20110183374A1 (en) 2011-07-28
EP2647647A2 (en) 2013-10-09
JP2010535481A (ja) 2010-11-25
CA2695813A1 (en) 2009-02-12
EP2178907A1 (en) 2010-04-28
CN101809030A (zh) 2010-08-18
CN103483424A (zh) 2014-01-01
BRPI0815371A2 (pt) 2015-02-10
WO2009019289A1 (en) 2009-02-12
AU2008285655B2 (en) 2012-03-08

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Legal Events

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