MX2009011692A - Uso de inhibidores de desacetilasa de histona (hdac) para el tratamiento de canceres gastrointestinales. - Google Patents

Uso de inhibidores de desacetilasa de histona (hdac) para el tratamiento de canceres gastrointestinales.

Info

Publication number
MX2009011692A
MX2009011692A MX2009011692A MX2009011692A MX2009011692A MX 2009011692 A MX2009011692 A MX 2009011692A MX 2009011692 A MX2009011692 A MX 2009011692A MX 2009011692 A MX2009011692 A MX 2009011692A MX 2009011692 A MX2009011692 A MX 2009011692A
Authority
MX
Mexico
Prior art keywords
treatment
gastrointestinal cancers
hdac inhibitors
hdac inhibitor
gastrointestinal
Prior art date
Application number
MX2009011692A
Other languages
English (en)
Inventor
Peter Wisdom Atadja
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39683987&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2009011692(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MX2009011692A publication Critical patent/MX2009011692A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • A61K31/4045Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

La presente invención se refiere al uso de un inhibidor de desacetilasa de histona, para la preparación de un medicamento para el tratamiento de cánceres gastrointestinales; a un método para el tratamiento de un animal de sangre caliente, en especial un ser humano, que tenga cáncer gastrointestinal, el cual comprende administrar a este animal una cantidad terapéuticamente efectiva de un inhibidor de desacetilasa de histona, en especial un compuesto de la fórmula (I), como se define en la presente; y a una composición farmacéutica y un paquete comercial.
MX2009011692A 2007-05-04 2008-05-02 Uso de inhibidores de desacetilasa de histona (hdac) para el tratamiento de canceres gastrointestinales. MX2009011692A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US91599607P 2007-05-04 2007-05-04
PCT/US2008/062341 WO2008137630A1 (en) 2007-05-04 2008-05-02 Use of hdac inhibitors for the treatment of gastrointestinal cancers

Publications (1)

Publication Number Publication Date
MX2009011692A true MX2009011692A (es) 2009-11-10

Family

ID=39683987

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009011692A MX2009011692A (es) 2007-05-04 2008-05-02 Uso de inhibidores de desacetilasa de histona (hdac) para el tratamiento de canceres gastrointestinales.

Country Status (16)

Country Link
EP (1) EP2142190A1 (es)
JP (1) JP2010526149A (es)
KR (1) KR20100016171A (es)
CN (1) CN101674825A (es)
AU (1) AU2008247603A1 (es)
BR (1) BRPI0811112A2 (es)
CA (1) CA2683554A1 (es)
CL (1) CL2008001269A1 (es)
IL (1) IL201318A0 (es)
MA (1) MA31356B1 (es)
MX (1) MX2009011692A (es)
RU (1) RU2009144842A (es)
TN (1) TN2009000427A1 (es)
TW (1) TW200908964A (es)
WO (1) WO2008137630A1 (es)
ZA (1) ZA200906739B (es)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20020354A1 (es) * 2000-09-01 2002-06-12 Novartis Ag Compuestos de hidroxamato como inhibidores de histona-desacetilasa (hda)
AU2004284030A1 (en) * 2003-10-27 2005-05-06 S*Bio Pte Ltd Acylurea connected and sulfonylurea connected hydroxamates
TW200524575A (en) * 2003-10-27 2005-08-01 S Bio Pte Ltd Biaryl linked hydroxamates: preparation and pharmaceutical applications
WO2006075165A1 (en) * 2005-01-13 2006-07-20 Btg International Limited Combination of oncolytic viruses with angiogenesis inhibitors

Also Published As

Publication number Publication date
EP2142190A1 (en) 2010-01-13
IL201318A0 (en) 2010-05-31
JP2010526149A (ja) 2010-07-29
TN2009000427A1 (en) 2011-03-31
TW200908964A (en) 2009-03-01
BRPI0811112A2 (pt) 2014-12-23
CA2683554A1 (en) 2008-11-13
KR20100016171A (ko) 2010-02-12
ZA200906739B (en) 2010-06-30
CL2008001269A1 (es) 2008-12-19
RU2009144842A (ru) 2011-06-10
MA31356B1 (fr) 2010-05-03
CN101674825A (zh) 2010-03-17
WO2008137630A1 (en) 2008-11-13
AU2008247603A1 (en) 2008-11-13

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Legal Events

Date Code Title Description
HH Correction or change in general
FA Abandonment or withdrawal